sulfadimethoxine-7400 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

194 genes differentially expressed following the sulfadimethoxine-7400 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACE angiotensin I converting enzyme
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1
APOA4 apolipoprotein A-IV
AVPR1A arginine vasopressin receptor 1A
BAHCC1 BAH domain and coiled-coil containing 1
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BDKRB1 bradykinin receptor B1
BIRC7 baculoviral IAP repeat containing 7
CAMTA1 calmodulin binding transcription activator 1
CASP1 caspase 1, apoptosis-related cysteine peptidase
CD40 CD40 molecule, TNF receptor superfamily member 5
CD58 CD58 molecule
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLCA1 chloride channel accessory 1
CLDN11 claudin 11
COL8A1 collagen, type VIII, alpha 1
CSHL1 chorionic somatomammotropin hormone-like 1
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DCTN1 dynactin 1
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DFNB31 deafness, autosomal recessive 31
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
DNAH17 dynein, axonemal, heavy chain 17
DPF3 D4, zinc and double PHD fingers, family 3
EDN1 endothelin 1
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
ERAP1 endoplasmic reticulum aminopeptidase 1
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FOXN3 forkhead box N3
GYPB glycophorin B (MNS blood group)
HEG1 heart development protein with EGF-like domains 1
HEMK1 HemK methyltransferase family member 1
HIST1H4F histone cluster 1, H4f
HOXA1 homeobox A1
HRK harakiri, BCL2 interacting protein
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
IGFBP5 insulin-like growth factor binding protein 5
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IL6 interleukin 6
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KIAA1644 KIAA1644
KIF13A kinesin family member 13A
LIMD2 LIM domain containing 2
MAG myelin associated glycoprotein
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MATN3 matrilin 3
MDFIC MyoD family inhibitor domain containing
METTL7A methyltransferase like 7A
MFAP3L microfibrillar-associated protein 3-like
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MLX MLX, MAX dimerization protein
MYOF myoferlin
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NCOR2 nuclear receptor corepressor 2
NLGN1 neuroligin 1
NNMT nicotinamide N-methyltransferase
NRF1 nuclear respiratory factor 1
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PDGFB platelet-derived growth factor beta polypeptide
PDS5A PDS5 cohesin associated factor A
PLEKHO2 pleckstrin homology domain containing, family O member 2
PLK4 polo-like kinase 4
PLSCR1 phospholipid scramblase 1
POMT2 protein-O-mannosyltransferase 2
PPP1R3D protein phosphatase 1, regulatory subunit 3D
PRO2964 uncharacterized protein PRO2964
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic)
RAD52 RAD52 homolog (S. cerevisiae)
RBM48 RNA binding motif protein 48
RCE1 Ras converting CAAX endopeptidase 1
RCN3 reticulocalbin 3, EF-hand calcium binding domain
RPL7 ribosomal protein L7
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SETD8 SET domain containing (lysine methyltransferase) 8
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SNX1 sorting nexin 1
SOX4 SRY (sex determining region Y)-box 4
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3
SRSF5 serine/arginine-rich splicing factor 5
STAB2 stabilin 2
TBCD tubulin folding cofactor D
TMEM259 transmembrane protein 259
TRAF2 TNF receptor-associated factor 2
TRAPPC13 trafficking protein particle complex 13
TTC12 tetratricopeptide repeat domain 12
TTLL1 tubulin tyrosine ligase-like family member 1
UBE3A ubiquitin protein ligase E3A
ZBTB22 zinc finger and BTB domain containing 22
ZBTB7A zinc finger and BTB domain containing 7A
ZNF222 zinc finger protein 222
ZNF276 zinc finger protein 276
ZNF280A zinc finger protein 280A
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ADGRG2 adhesion G protein-coupled receptor G2
AGMAT agmatine ureohydrolase (agmatinase)
ALKBH1 alkB, alkylation repair homolog 1 (E. coli)
ANKZF1 ankyrin repeat and zinc finger domain containing 1
APOL6 apolipoprotein L, 6
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATP10D ATPase, class V, type 10D
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BAG4 BCL2-associated athanogene 4
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide
BCL9 B-cell CLL/lymphoma 9
BRAF B-Raf proto-oncogene, serine/threonine kinase
C1ORF159 chromosome 1 open reading frame 159
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCNT1 cyclin T1
CD79B CD79b molecule, immunoglobulin-associated beta
CDH7 cadherin 7, type 2
CLEC16A C-type lectin domain family 16, member A
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CRELD1 cysteine-rich with EGF-like domains 1
CTSK cathepsin K
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DCAF10 DDB1 and CUL4 associated factor 10
DCAF13 DDB1 and CUL4 associated factor 13
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
ELOVL4 ELOVL fatty acid elongase 4
EN2 engrailed homeobox 2
EPHA4 EPH receptor A4
FKBP10 FK506 binding protein 10, 65 kDa
FLCN folliculin
FSTL3 follistatin-like 3 (secreted glycoprotein)
GAREM GRB2 associated, regulator of MAPK1
GNL1 guanine nucleotide binding protein-like 1
GRWD1 glutamate-rich WD repeat containing 1
GSTA3 glutathione S-transferase alpha 3
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BO histone cluster 1, H2bo
HIST1H3A histone cluster 1, H3a
HOMER2 homer scaffolding protein 2
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
IFI35 interferon-induced protein 35
IFI6 interferon, alpha-inducible protein 6
IPO8 importin 8
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
IQCC IQ motif containing C
KIAA1107 KIAA1107
KPNA5 karyopherin alpha 5 (importin alpha 6)
LOC202181 SUMO-interacting motifs containing 1 pseudogene
MANBA mannosidase, beta A, lysosomal
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MCM9 minichromosome maintenance complex component 9
MED15 mediator complex subunit 15
NAG18 NAG18 mRNA
NINJ1 ninjurin 1
NR1H3 nuclear receptor subfamily 1, group H, member 3
NT5M 5',3'-nucleotidase, mitochondrial
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
PEX26 peroxisomal biogenesis factor 26
PGAP1 post-GPI attachment to proteins 1
PLCD1 phospholipase C, delta 1
PLEKHA6 pleckstrin homology domain containing, family A member 6
POLL polymerase (DNA directed), lambda
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PTGES2 prostaglandin E synthase 2
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)
RAB20 RAB20, member RAS oncogene family
RAB4B RAB4B, member RAS oncogene family
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
REPS2 RALBP1 associated Eps domain containing 2
RIN1 Ras and Rab interactor 1
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
STAC SH3 and cysteine rich domain
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STIM1 stromal interaction molecule 1
STX1A syntaxin 1A (brain)
TEP1 telomerase-associated protein 1
TGFB3 transforming growth factor, beta 3
TGFBI transforming growth factor, beta-induced, 68kDa
TIMP4 TIMP metallopeptidase inhibitor 4
TNNI3 troponin I type 3 (cardiac)
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TTC31 tetratricopeptide repeat domain 31
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VLDLR very low density lipoprotein receptor
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
ZFHX2 zinc finger homeobox 2