sulfadimidine-2560 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the sulfadimidine-2560 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A2M alpha-2-macroglobulin
AASS aminoadipate-semialdehyde synthase
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ACSBG1 acyl-CoA synthetase bubblegum family member 1
AGER advanced glycosylation end product-specific receptor
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BRSK2 BR serine/threonine kinase 2
CA12 carbonic anhydrase XII
CAMP cathelicidin antimicrobial peptide
CD52 CD52 molecule
CD6 CD6 molecule
CEACAM21 carcinoembryonic antigen-related cell adhesion molecule 21
CHRM2 cholinergic receptor, muscarinic 2
CLDN17 claudin 17
COL8A1 collagen, type VIII, alpha 1
CST1 cystatin SN
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DRD2 dopamine receptor D2
DUX4L8 double homeobox 4 like 8
EDDM3B epididymal protein 3B
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FABP3 fatty acid binding protein 3, muscle and heart
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
FBXL7 F-box and leucine-rich repeat protein 7
FGF8 fibroblast growth factor 8 (androgen-induced)
FLJ11292
FRS3 fibroblast growth factor receptor substrate 3
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GABRD gamma-aminobutyric acid (GABA) A receptor, delta
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GRIK5 glutamate receptor, ionotropic, kainate 5
GSPT1 G1 to S phase transition 1
HDAC7 histone deacetylase 7
HOXA10 homeobox A10
HOXC13 homeobox C13
HPR haptoglobin-related protein
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
HYAL1 hyaluronoglucosaminidase 1
ICAM5 intercellular adhesion molecule 5, telencephalin
IFITM1 interferon induced transmembrane protein 1
IGH immunoglobulin heavy locus
IL3RA interleukin 3 receptor, alpha (low affinity)
IRF5 interferon regulatory factor 5
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KIDINS220 kinase D-interacting substrate, 220kDa
KIF1C kinesin family member 1C
KLF3 Kruppel-like factor 3 (basic)
KRT23 keratin 23, type I
KYNU kynureninase
LBX1 ladybird homeobox 1
LLGL1 lethal giant larvae homolog 1 (Drosophila)
MAPT microtubule-associated protein tau
MEG3 maternally expressed 3 (non-protein coding)
MET MET proto-oncogene, receptor tyrosine kinase
MR1 major histocompatibility complex, class I-related
MRC2 mannose receptor, C type 2
NCOR2 nuclear receptor corepressor 2
NFE2L3 nuclear factor, erythroid 2-like 3
NIPAL3 NIPA-like domain containing 3
PAX2 paired box 2
PCLO piccolo presynaptic cytomatrix protein
PEG3 paternally expressed 3
PKD2L2 polycystic kidney disease 2-like 2
PKNOX2 PBX/knotted 1 homeobox 2
PLIN2 perilipin 2
PRB1 proline-rich protein BstNI subfamily 1
PRUNE2 prune homolog 2 (Drosophila)
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
REC8 REC8 meiotic recombination protein
RGS10 regulator of G-protein signaling 10
RUNDC3A RUN domain containing 3A
SIGLEC6 sialic acid binding Ig-like lectin 6
SLC16A6 solute carrier family 16, member 6
SLC35F6 solute carrier family 35, member F6
SLCO3A1 solute carrier organic anion transporter family, member 3A1
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
SSX3 synovial sarcoma, X breakpoint 3
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
STEAP4 STEAP family member 4
TACSTD2 tumor-associated calcium signal transducer 2
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TCL6 T-cell leukemia/lymphoma 6 (non-protein coding)
THPO thrombopoietin
TRIM14 tripartite motif containing 14
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
UTF1 undifferentiated embryonic cell transcription factor 1
VEGFC vascular endothelial growth factor C
WNT8B wingless-type MMTV integration site family, member 8B
WSCD1 WSC domain containing 1
ZNF177 zinc finger protein 177
ZNF484 zinc finger protein 484

decreased expression

Symbol Name
AGBL5 ATP/GTP binding protein-like 5
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARMC7 armadillo repeat containing 7
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
ARRB1 arrestin, beta 1
ATP10D ATPase, class V, type 10D
BAG4 BCL2-associated athanogene 4
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
C11ORF71 chromosome 11 open reading frame 71
C12ORF29 chromosome 12 open reading frame 29
C12ORF49 chromosome 12 open reading frame 49
C21ORF91 chromosome 21 open reading frame 91
C22ORF29 chromosome 22 open reading frame 29
C2CD2 C2 calcium-dependent domain containing 2
CCDC6 coiled-coil domain containing 6
CDK20 cyclin-dependent kinase 20
CDK7 cyclin-dependent kinase 7
CEP70 centrosomal protein 70kDa
CHML choroideremia-like (Rab escort protein 2)
CHMP6 charged multivesicular body protein 6
CTPS2 CTP synthase 2
CTSL cathepsin L
DNA2 DNA replication helicase/nuclease 2
DOLK dolichol kinase
DTX4 deltex 4, E3 ubiquitin ligase
ENO3 enolase 3 (beta, muscle)
ERAP2 endoplasmic reticulum aminopeptidase 2
ETV6 ets variant 6
F8 coagulation factor VIII, procoagulant component
FAM188A family with sequence similarity 188, member A
FBXL6 F-box and leucine-rich repeat protein 6
FKBPL FK506 binding protein like
GALK1 galactokinase 1
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GPR85 G protein-coupled receptor 85
GTF2I general transcription factor IIi
KIFC1 kinesin family member C1
KLHL21 kelch-like family member 21
KLHL26 kelch-like family member 26
LIN7A lin-7 homolog A (C. elegans)
LMNB1 lamin B1
LRP5 low density lipoprotein receptor-related protein 5
LTB lymphotoxin beta (TNF superfamily, member 3)
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MBTPS2 membrane-bound transcription factor peptidase, site 2
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
METTL16 methyltransferase like 16
MYL5 myosin, light chain 5, regulatory
NHEJ1 nonhomologous end-joining factor 1
NR2C2 nuclear receptor subfamily 2, group C, member 2
PARP16 poly (ADP-ribose) polymerase family, member 16
PHC1 polyhomeotic homolog 1 (Drosophila)
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PJA1 praja ring finger 1, E3 ubiquitin protein ligase
PLA2G12A phospholipase A2, group XIIA
PMCH pro-melanin-concentrating hormone
POMZP3 POM121 and ZP3 fusion
PRICKLE3 prickle homolog 3 (Drosophila)
PRMT7 protein arginine methyltransferase 7
PROSER1 proline and serine rich 1
PTCD2 pentatricopeptide repeat domain 2
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
PWAR5 Prader Willi/Angelman region RNA 5
RAB3A RAB3A, member RAS oncogene family
RC3H2 ring finger and CCCH-type domains 2
RNF122 ring finger protein 122
RPL23AP7 ribosomal protein L23a pseudogene 7
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
SCYL2 SCY1-like 2 (S. cerevisiae)
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae)
SERINC5 serine incorporator 5
SETD8 SET domain containing (lysine methyltransferase) 8
SIDT1 SID1 transmembrane family, member 1
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2
SLFN12 schlafen family member 12
STBD1 starch binding domain 1
STK16 serine/threonine kinase 16
SUGP1 SURP and G patch domain containing 1
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
TCTA T-cell leukemia translocation altered
TMEM242 transmembrane protein 242
TMEM53 transmembrane protein 53
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TWF2 twinfilin actin binding protein 2
TXLNG taxilin gamma
UNC119 unc-119 homolog (C. elegans)
UNC93B1 unc-93 homolog B1 (C. elegans)
URM1 ubiquitin related modifier 1
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
ZBTB24 zinc finger and BTB domain containing 24
ZDHHC14 zinc finger, DHHC-type containing 14
ZMAT5 zinc finger, matrin-type 5
ZNF232 zinc finger protein 232
ZNF668 zinc finger protein 668
ZNF675 zinc finger protein 675
ZNF74 zinc finger protein 74
ZNF76 zinc finger protein 76
ZNHIT2 zinc finger, HIT-type containing 2