sulfadimidine-3422 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the sulfadimidine-3422 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
AKAP8L A kinase (PRKA) anchor protein 8-like
ARHGAP35 Rho GTPase activating protein 35
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATF5 activating transcription factor 5
ATF6B activating transcription factor 6 beta
ATM ATM serine/threonine kinase
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1
BCAP29 B-cell receptor-associated protein 29
BTBD7 BTB (POZ) domain containing 7
C3ORF18 chromosome 3 open reading frame 18
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CCNO cyclin O
CD82 CD82 molecule
CDC14A cell division cycle 14A
CDH8 cadherin 8, type 2
CDK13 cyclin-dependent kinase 13
CFLAR CASP8 and FADD-like apoptosis regulator
CLCA1 chloride channel accessory 1
CLIP4 CAP-GLY domain containing linker protein family, member 4
COMT catechol-O-methyltransferase
CXADR coxsackie virus and adenovirus receptor
DAPK3 death-associated protein kinase 3
E2F4 E2F transcription factor 4, p107/p130-binding
EHD1 EH-domain containing 1
EMID1 EMI domain containing 1
FAM204A family with sequence similarity 204, member A
FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial
FBXO9 F-box protein 9
GAB1 GRB2-associated binding protein 1
GREB1 growth regulation by estrogen in breast cancer 1
GSDMB gasdermin B
HDAC7 histone deacetylase 7
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HOXC5 homeobox C5
IFT54 intraflagellar transport 54
IGHA1 immunoglobulin heavy constant alpha 1
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
KHK ketohexokinase (fructokinase)
LOC100131532 uncharacterized LOC100131532
LPPR2 lipid phosphate phosphatase-related protein type 2
MAN1C1 mannosidase, alpha, class 1C, member 1
MAST3 microtubule associated serine/threonine kinase 3
MED25 mediator complex subunit 25
MXD3 MAX dimerization protein 3
MYL10 myosin, light chain 10, regulatory
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NFX1 nuclear transcription factor, X-box binding 1
NKX3-2 NK3 homeobox 2
NPIPB3 nuclear pore complex interacting protein family, member B3
OR2B6 olfactory receptor, family 2, subfamily B, member 6
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PDGFB platelet-derived growth factor beta polypeptide
PEX16 peroxisomal biogenesis factor 16
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
PLXNA3 plexin A3
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F
PRB3 proline-rich protein BstNI subfamily 3
PRDM16 PR domain containing 16
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PTRF polymerase I and transcript release factor
PVR poliovirus receptor
QPCTL glutaminyl-peptide cyclotransferase-like
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RABGAP1 RAB GTPase activating protein 1
RAD52 RAD52 homolog (S. cerevisiae)
RGCC regulator of cell cycle
RPL10L ribosomal protein L10-like
RPS28 ribosomal protein S28
RTEL1 regulator of telomere elongation helicase 1
SFRP4 secreted frizzled-related protein 4
SH3BP2 SH3-domain binding protein 2
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SMR3A submaxillary gland androgen regulated protein 3A
SOCS1 suppressor of cytokine signaling 1
STC1 stanniocalcin 1
STS steroid sulfatase (microsomal), isozyme S
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TBC1D22A TBC1 domain family, member 22A
TBX19 T-box 19
TM2D1 TM2 domain containing 1
TMPRSS2 transmembrane protease, serine 2
TOP3A topoisomerase (DNA) III alpha
TRIM29 tripartite motif containing 29
TTC38 tetratricopeptide repeat domain 38
TUBA4B tubulin, alpha 4b
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VLDLR very low density lipoprotein receptor
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
WLS wntless Wnt ligand secretion mediator
WSB1 WD repeat and SOCS box containing 1
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF10 zinc finger protein 10
ZNF41 zinc finger protein 41

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ATAD2B ATPase family, AAA domain containing 2B
ATAD3A ATPase family, AAA domain containing 3A
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATG2B autophagy related 2B
BCL9 B-cell CLL/lymphoma 9
BFSP1 beaded filament structural protein 1, filensin
BPGM 2,3-bisphosphoglycerate mutase
C16ORF59 chromosome 16 open reading frame 59
C7ORF43 chromosome 7 open reading frame 43
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CCNL2 cyclin L2
CDC42BPB CDC42 binding protein kinase beta (DMPK-like)
CDC50A cell division cycle 50 P4-ATPase accessory subunit A
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta
CENPC centromere protein C
CEP170B centrosomal protein 170B
CHKB choline kinase beta
CHMP7 charged multivesicular body protein 7
CHST10 carbohydrate sulfotransferase 10
CIC capicua transcriptional repressor
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DACH1 dachshund family transcription factor 1
DENND4A DENN/MADD domain containing 4A
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DMXL1 Dmx-like 1
DNM1 dynamin 1
E4F1 E4F transcription factor 1
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
ELOVL4 ELOVL fatty acid elongase 4
FBXL15 F-box and leucine-rich repeat protein 15
FBXO22 F-box protein 22
FBXO31 F-box protein 31
FGF23 fibroblast growth factor 23
FKBP10 FK506 binding protein 10, 65 kDa
FOCAD focadhesin
FPGS folylpolyglutamate synthase
FURIN furin (paired basic amino acid cleaving enzyme)
GLTSCR1 glioma tumor suppressor candidate region gene 1
GTPBP6 GTP binding protein 6 (putative)
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
ICK intestinal cell (MAK-like) kinase
IRF6 interferon regulatory factor 6
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
LIG4 ligase IV, DNA, ATP-dependent
LINS lines homolog (Drosophila)
LRP5 low density lipoprotein receptor-related protein 5
LRP5L low density lipoprotein receptor-related protein 5-like
LRRC61 leucine rich repeat containing 61
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LY6G5C lymphocyte antigen 6 complex, locus G5C
MNT MAX network transcriptional repressor
MTMR11 myotubularin related protein 11
MYO19 myosin XIX
NECAP2 NECAP endocytosis associated 2
NT5DC3 5'-nucleotidase domain containing 3
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
OTUD3 OTU deubiquitinase 3
PCDHB3 protocadherin beta 3
PELI1 pellino E3 ubiquitin protein ligase 1
PGPEP1 pyroglutamyl-peptidase I
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PLA2G3 phospholipase A2, group III
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
SKA1 spindle and kinetochore associated complex subunit 1
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SNUPN snurportin 1
SNX16 sorting nexin 16
SPATA7 spermatogenesis associated 7
SRD5A3 steroid 5 alpha-reductase 3
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STARD5 StAR-related lipid transfer (START) domain containing 5
STXBP2 syntaxin binding protein 2
THAP1 THAP domain containing, apoptosis associated protein 1
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast)
TPST2 tyrosylprotein sulfotransferase 2
TRAIP TRAF interacting protein
TRIM25 tripartite motif containing 25
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
TTC4 tetratricopeptide repeat domain 4
TUBA3D tubulin, alpha 3d
UBXN6 UBX domain protein 6
WDR25 WD repeat domain 25
WDR60 WD repeat domain 60
XK X-linked Kx blood group
ZNF282 zinc finger protein 282
ZNF350 zinc finger protein 350
ZNF365 zinc finger protein 365
ZNF552 zinc finger protein 552
ZNF675 zinc finger protein 675
ZNF862 zinc finger protein 862
ZSCAN9 zinc finger and SCAN domain containing 9