sulfadimidine-3940 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the sulfadimidine-3940 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4
AGMAT agmatine ureohydrolase (agmatinase)
ANTXR1 anthrax toxin receptor 1
AP3B2 adaptor-related protein complex 3, beta 2 subunit
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
APOC4 apolipoprotein C-IV
APOL6 apolipoprotein L, 6
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ARL3 ADP-ribosylation factor-like 3
ASMT acetylserotonin O-methyltransferase
ATP1B2 ATPase, Na+/K+ transporting, beta 2 polypeptide
BAX BCL2-associated X protein
BIRC3 baculoviral IAP repeat containing 3
C11ORF16 chromosome 11 open reading frame 16
C21ORF2 chromosome 21 open reading frame 2
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CCL5 chemokine (C-C motif) ligand 5
CCNJL cyclin J-like
CCZ1 CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
CDIP1 cell death-inducing p53 target 1
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CLSTN3 calsyntenin 3
CLTA clathrin, light chain A
COL1A1 collagen, type I, alpha 1
CTRC chymotrypsin C (caldecrin)
CTSZ cathepsin Z
CXCR6 chemokine (C-X-C motif) receptor 6
CYB5R2 cytochrome b5 reductase 2
DGCR8 DGCR8 microprocessor complex subunit
DUSP6 dual specificity phosphatase 6
ELAVL4 ELAV like neuron-specific RNA binding protein 4
ELL2 elongation factor, RNA polymerase II, 2
ELN elastin
EPN1 epsin 1
ERCC2 excision repair cross-complementation group 2
FAIM2 Fas apoptotic inhibitory molecule 2
FGFBP1 fibroblast growth factor binding protein 1
FOXG1 forkhead box G1
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GRM7 glutamate receptor, metabotropic 7
GUSBP3 glucuronidase, beta pseudogene 3
HIRA histone cell cycle regulator
ICA1 islet cell autoantigen 1, 69kDa
IGLJ3 immunoglobulin lambda joining 3
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KREMEN2 kringle containing transmembrane protein 2
LRP1B low density lipoprotein receptor-related protein 1B
MAGEC1 melanoma antigen family C1
MAS1 MAS1 proto-oncogene, G protein-coupled receptor
MXRA5 matrix-remodelling associated 5
MYL4 myosin, light chain 4, alkali; atrial, embryonic
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NBL1 neuroblastoma 1, DAN family BMP antagonist
NHLH2 nescient helix loop helix 2
NKX2-8 NK2 homeobox 8
NUP88 nucleoporin 88kDa
P3H2 prolyl 3-hydroxylase 2
PAPPA2 pappalysin 2
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCDH7 protocadherin 7
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PER1 period circadian clock 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PKP1 plakophilin 1
PMEL premelanosome protein
POLL polymerase (DNA directed), lambda
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRDM12 PR domain containing 12
PRSS3 protease, serine, 3
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RAP1GAP RAP1 GTPase activating protein
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RGS14 regulator of G-protein signaling 14
RPL23AP53 ribosomal protein L23a pseudogene 53
RUNX1 runt-related transcription factor 1
SAFB scaffold attachment factor B
SAYSD1 SAYSVFN motif domain containing 1
SECTM1 secreted and transmembrane 1
SIGLEC7 sialic acid binding Ig-like lectin 7
SIM2 single-minded family bHLH transcription factor 2
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SOX10 SRY (sex determining region Y)-box 10
SSTR5 somatostatin receptor 5
SUGP1 SURP and G patch domain containing 1
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
TEX14 testis expressed 14
TSC2 tuberous sclerosis 2
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
WNT16 wingless-type MMTV integration site family, member 16
ZC4H2 zinc finger, C4H2 domain containing
ZNF280A zinc finger protein 280A
ZNF702P zinc finger protein 702, pseudogene

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
ABHD4 abhydrolase domain containing 4
ARC activity-regulated cytoskeleton-associated protein
ARMC4 armadillo repeat containing 4
ATAT1 alpha tubulin acetyltransferase 1
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BAHD1 bromo adjacent homology domain containing 1
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BMP10 bone morphogenetic protein 10
C17ORF53 chromosome 17 open reading frame 53
CDHR2 cadherin-related family member 2
CES3 carboxylesterase 3
CFHR4 complement factor H-related 4
CIDEB cell death-inducing DFFA-like effector b
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CLCN6 chloride channel, voltage-sensitive 6
CLIP4 CAP-GLY domain containing linker protein family, member 4
DCBLD2 discoidin, CUB and LCCL domain containing 2
DGKE diacylglycerol kinase, epsilon 64kDa
DOK5 docking protein 5
DSCAM Down syndrome cell adhesion molecule
FAM120C family with sequence similarity 120C
FAM76A family with sequence similarity 76, member A
FILIP1L filamin A interacting protein 1-like
FKBP5 FK506 binding protein 5
FLJ11710 uncharacterized protein FLJ11710
GAST gastrin
GMIP GEM interacting protein
GPR143 G protein-coupled receptor 143
GPR27 G protein-coupled receptor 27
GREB1L growth regulation by estrogen in breast cancer-like
HDAC5 histone deacetylase 5
HIST1H4E histone cluster 1, H4e
HIST1H4F histone cluster 1, H4f
IFI6 interferon, alpha-inducible protein 6
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
KCNK5 potassium channel, two pore domain subfamily K, member 5
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KIF13A kinesin family member 13A
LMO7 LIM domain 7
LPPR1 lipid phosphate phosphatase-related protein type 1
MAP9 microtubule-associated protein 9
MAPK8 mitogen-activated protein kinase 8
MAPKBP1 mitogen-activated protein kinase binding protein 1
NOL10 nucleolar protein 10
NOTCH4 notch 4
NPFFR1 neuropeptide FF receptor 1
NPY4R neuropeptide Y receptor Y4
OCA2 oculocutaneous albinism II
OR2B6 olfactory receptor, family 2, subfamily B, member 6
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
OVOL1 ovo-like zinc finger 1
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLEKHO2 pleckstrin homology domain containing, family O member 2
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PRKCE protein kinase C, epsilon
PSG4 pregnancy specific beta-1-glycoprotein 4
PTPRM protein tyrosine phosphatase, receptor type, M
PYHIN1 pyrin and HIN domain family, member 1
RFPL3 ret finger protein-like 3
RHBDD3 rhomboid domain containing 3
RLN1 relaxin 1
RND1 Rho family GTPase 1
RNF126P1 ring finger protein 126 pseudogene 1
RNF208 ring finger protein 208
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPAP1 RNA polymerase II associated protein 1
SAA4 serum amyloid A4, constitutive
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SETD8 SET domain containing (lysine methyltransferase) 8
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SPRR1B small proline-rich protein 1B
SPTBN2 spectrin, beta, non-erythrocytic 2
TEX40 testis expressed 40
TGFBR1 transforming growth factor, beta receptor 1
TLR5 toll-like receptor 5
TM4SF5 transmembrane 4 L six family member 5
TRAIP TRAF interacting protein
TTLL1 tubulin tyrosine ligase-like family member 1
TYRP1 tyrosinase-related protein 1
UBXN6 UBX domain protein 6
YY2 YY2 transcription factor
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF442 zinc finger protein 442
ZNF446 zinc finger protein 446
ZNF484 zinc finger protein 484
ZNF639 zinc finger protein 639