| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the sulfadoxine-5852 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTN2 | actinin, alpha 2 |
| ACVR1B | activin A receptor, type IB |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| ADRBK2 | adrenergic, beta, receptor kinase 2 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 |
| ARMC4 | armadillo repeat containing 4 |
| ARRB2 | arrestin, beta 2 |
| ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
| ATP10A | ATPase, class V, type 10A |
| ATPAF2 | ATP synthase mitochondrial F1 complex assembly factor 2 |
| BCL2 | B-cell CLL/lymphoma 2 |
| CCNG2 | cyclin G2 |
| CCNO | cyclin O |
| CELSR2 | cadherin, EGF LAG seven-pass G-type receptor 2 |
| CEP68 | centrosomal protein 68kDa |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| COL21A1 | collagen, type XXI, alpha 1 |
| CYLD | cylindromatosis (turban tumor syndrome) |
| CYP2E1 | cytochrome P450, family 2, subfamily E, polypeptide 1 |
| DBF4B | DBF4 zinc finger B |
| DLX4 | distal-less homeobox 4 |
| EFNB3 | ephrin-B3 |
| EGR1 | early growth response 1 |
| FABP3 | fatty acid binding protein 3, muscle and heart |
| FBXO22 | F-box protein 22 |
| FCER1G | Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide |
| FOXG1 | forkhead box G1 |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| FXR2 | fragile X mental retardation, autosomal homolog 2 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GOLGA8A | golgin A8 family, member A |
| GPR85 | G protein-coupled receptor 85 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| GRTP1 | growth hormone regulated TBC protein 1 |
| HOXA4 | homeobox A4 |
| HYAL3 | hyaluronoglucosaminidase 3 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IL1R1 | interleukin 1 receptor, type I |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KDM4C | lysine (K)-specific demethylase 4C |
| KLHL1 | kelch-like family member 1 |
| KRIT1 | KRIT1, ankyrin repeat containing |
| KRT6B | keratin 6B, type II |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LMAN1 | lectin, mannose-binding, 1 |
| LPL | lipoprotein lipase |
| LRRC61 | leucine rich repeat containing 61 |
| MASP2 | mannan-binding lectin serine peptidase 2 |
| MBD2 | methyl-CpG binding domain protein 2 |
| MBIP | MAP3K12 binding inhibitory protein 1 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MED31 | mediator complex subunit 31 |
| MERTK | MER proto-oncogene, tyrosine kinase |
| MFAP3L | microfibrillar-associated protein 3-like |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| MXD3 | MAX dimerization protein 3 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) |
| NEK3 | NIMA-related kinase 3 |
| NELL2 | NEL-like 2 (chicken) |
| NMT2 | N-myristoyltransferase 2 |
| OSBPL10 | oxysterol binding protein-like 10 |
| PLCD1 | phospholipase C, delta 1 |
| PON1 | paraoxonase 1 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PRPF18 | pre-mRNA processing factor 18 |
| PTBP3 | polypyrimidine tract binding protein 3 |
| QKI | QKI, KH domain containing, RNA binding |
| RAD54B | RAD54 homolog B (S. cerevisiae) |
| RIMBP2 | RIMS binding protein 2 |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| RUSC2 | RUN and SH3 domain containing 2 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SENP5 | SUMO1/sentrin specific peptidase 5 |
| SIRT5 | sirtuin 5 |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SMAD4 | SMAD family member 4 |
| SOGA1 | suppressor of glucose, autophagy associated 1 |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| TBC1D1 | TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 |
| TBC1D17 | TBC1 domain family, member 17 |
| TCF3 | transcription factor 3 |
| TESPA1 | thymocyte expressed, positive selection associated 1 |
| TPR | translocated promoter region, nuclear basket protein |
| TUBA8 | tubulin, alpha 8 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| VAMP2 | vesicle-associated membrane protein 2 (synaptobrevin 2) |
| VCAN | versican |
| WIPF1 | WAS/WASL interacting protein family, member 1 |
| WIZ | widely interspaced zinc finger motifs |
| YIPF4 | Yip1 domain family, member 4 |
| YY1 | YY1 transcription factor |
| ZNF227 | zinc finger protein 227 |
| ZNF467 | zinc finger protein 467 |
| ZNF573 | zinc finger protein 573 |
| Symbol | Name |
|---|---|
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ANAPC2 | anaphase promoting complex subunit 2 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| ARHGEF5 | Rho guanine nucleotide exchange factor (GEF) 5 |
| ATP10D | ATPase, class V, type 10D |
| BAK1 | BCL2-antagonist/killer 1 |
| BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 |
| BEX1 | brain expressed, X-linked 1 |
| C11ORF80 | chromosome 11 open reading frame 80 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CAPN5 | calpain 5 |
| CCDC130 | coiled-coil domain containing 130 |
| CCS | copper chaperone for superoxide dismutase |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CEP85 | centrosomal protein 85kDa |
| CFAP69 | cilia and flagella associated protein 69 |
| CHRNA5 | cholinergic receptor, nicotinic, alpha 5 (neuronal) |
| CMTR1 | cap methyltransferase 1 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
| DCLRE1B | DNA cross-link repair 1B |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| EAF2 | ELL associated factor 2 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM160B2 | family with sequence similarity 160, member B2 |
| FBRS | fibrosin |
| FBXL2 | F-box and leucine-rich repeat protein 2 |
| FBXW12 | F-box and WD repeat domain containing 12 |
| GID4 | GID complex subunit 4 |
| GMIP | GEM interacting protein |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| HAMP | hepcidin antimicrobial peptide |
| HIST1H2AE | histone cluster 1, H2ae |
| HOXA1 | homeobox A1 |
| HOXB13 | homeobox B13 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IMPDH1 | IMP (inosine 5'-monophosphate) dehydrogenase 1 |
| INPPL1 | inositol polyphosphate phosphatase-like 1 |
| IREB2 | iron-responsive element binding protein 2 |
| IRF1 | interferon regulatory factor 1 |
| ITPKC | inositol-trisphosphate 3-kinase C |
| KIAA0232 | KIAA0232 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) |
| KRT31 | keratin 31, type I |
| KRT75 | keratin 75, type II |
| LOC100286895 | cell division cycle 27 homolog pseudogene |
| LPAR3 | lysophosphatidic acid receptor 3 |
| LSR | lipolysis stimulated lipoprotein receptor |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MED22 | mediator complex subunit 22 |
| MVP | major vault protein |
| NARFL | nuclear prelamin A recognition factor-like |
| NDE1 | nudE neurodevelopment protein 1 |
| NINL | ninein-like |
| NMRK1 | nicotinamide riboside kinase 1 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NRSN2 | neurensin 2 |
| NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor |
| OPLAH | 5-oxoprolinase (ATP-hydrolysing) |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PARD6A | par-6 family cell polarity regulator alpha |
| PGGT1B | protein geranylgeranyltransferase type I, beta subunit |
| PHGDH | phosphoglycerate dehydrogenase |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| POMT1 | protein-O-mannosyltransferase 1 |
| PRMT7 | protein arginine methyltransferase 7 |
| RIC8B | RIC8 guanine nucleotide exchange factor B |
| RNF122 | ring finger protein 122 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SERTAD3 | SERTA domain containing 3 |
| SLC39A1 | solute carrier family 39 (zinc transporter), member 1 |
| SND1-IT1 | SND1 intronic transcript 1 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SPAG4 | sperm associated antigen 4 |
| SYNPO | synaptopodin |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 |
| TBC1D19 | TBC1 domain family, member 19 |
| TCTN1 | tectonic family member 1 |
| TMC5 | transmembrane channel-like 5 |
| TMEM183A | transmembrane protein 183A |
| TRAPPC6A | trafficking protein particle complex 6A |
| TRIM66 | tripartite motif containing 66 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TTC23 | tetratricopeptide repeat domain 23 |
| USB1 | U6 snRNA biogenesis 1 |
| USP20 | ubiquitin specific peptidase 20 |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| ZNF10 | zinc finger protein 10 |
| ZNF426 | zinc finger protein 426 |
| ZNF668 | zinc finger protein 668 |