sulfafurazole-3218 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the sulfafurazole-3218 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADCY10 adenylate cyclase 10 (soluble)
ADD2 adducin 2 (beta)
AIM1L absent in melanoma 1-like
ALOX5 arachidonate 5-lipoxygenase
ALS2CL ALS2 C-terminal like
APAF1 apoptotic peptidase activating factor 1
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1
APOE apolipoprotein E
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARMCX2 armadillo repeat containing, X-linked 2
ATP10B ATPase, class V, type 10B
BCL2 B-cell CLL/lymphoma 2
BTN2A2 butyrophilin, subfamily 2, member A2
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCDC64 coiled-coil domain containing 64
CCDC69 coiled-coil domain containing 69
CDHR2 cadherin-related family member 2
CFLAR CASP8 and FADD-like apoptosis regulator
CHRM3 cholinergic receptor, muscarinic 3
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CLIP2 CAP-GLY domain containing linker protein 2
CNOT3 CCR4-NOT transcription complex, subunit 3
COPZ2 coatomer protein complex, subunit zeta 2
CPA4 carboxypeptidase A4
CTSF cathepsin F
CXCR2 chemokine (C-X-C motif) receptor 2
DGCR8 DGCR8 microprocessor complex subunit
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DNASE1 deoxyribonuclease I
DOCK6 dedicator of cytokinesis 6
DSC3 desmocollin 3
EFNB3 ephrin-B3
EMC1 ER membrane protein complex subunit 1
EPOR erythropoietin receptor
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
FCMR Fc fragment of IgM receptor
FGF5 fibroblast growth factor 5
FHL1 four and a half LIM domains 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FRMD4A FERM domain containing 4A
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GGT1 gamma-glutamyltransferase 1
GJA4 gap junction protein, alpha 4, 37kDa
GLRA1 glycine receptor, alpha 1
GLRX3 glutaredoxin 3
GRIK2 glutamate receptor, ionotropic, kainate 2
GRM1 glutamate receptor, metabotropic 1
GSTP1 glutathione S-transferase pi 1
HOXB6 homeobox B6
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
IDS iduronate 2-sulfatase
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
KRT83 keratin 83, type II
LAMC2 laminin, gamma 2
LRAT lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
LRP2 low density lipoprotein receptor-related protein 2
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MAGEA3 melanoma antigen family A3
MCTP2 multiple C2 domains, transmembrane 2
MEGF8 multiple EGF-like-domains 8
MGAM maltase-glucoamylase
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa
NTN3 netrin 3
PBX2 pre-B-cell leukemia homeobox 2
PCBP3 poly(rC) binding protein 3
PCNX pecanex homolog (Drosophila)
PHF14 PHD finger protein 14
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
POU2F2 POU class 2 homeobox 2
PRDM1 PR domain containing 1, with ZNF domain
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RPL5 ribosomal protein L5
SALL1 spalt-like transcription factor 1
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
SMAD3 SMAD family member 3
SNED1 sushi, nidogen and EGF-like domains 1
SNTA1 syntrophin, alpha 1
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SRRT serrate, RNA effector molecule
TGM2 transglutaminase 2
TKTL1 transketolase-like 1
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TTC38 tetratricopeptide repeat domain 38
TUBB7P tubulin, beta 7, pseudogene
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
WNT2 wingless-type MMTV integration site family member 2
ZNF259P1 zinc finger protein 259 pseudogene 1
ZNF287 zinc finger protein 287
ZNF551 zinc finger protein 551
ZNF639 zinc finger protein 639
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ABHD4 abhydrolase domain containing 4
ACAD10 acyl-CoA dehydrogenase family, member 10
ACSF2 acyl-CoA synthetase family member 2
ANXA2P3 annexin A2 pseudogene 3
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARSB arylsulfatase B
ART1 ADP-ribosyltransferase 1
BCL9 B-cell CLL/lymphoma 9
BTF3P11 basic transcription factor 3 pseudogene 11
CA5BP1 carbonic anhydrase VB pseudogene 1
CBX8 chromobox homolog 8
CCDC85C coiled-coil domain containing 85C
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CD83 CD83 molecule
CDKL3 cyclin-dependent kinase-like 3
CEP72 centrosomal protein 72kDa
CRY2 cryptochrome circadian clock 2
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
DGAT1 diacylglycerol O-acyltransferase 1
DTX4 deltex 4, E3 ubiquitin ligase
DUSP13 dual specificity phosphatase 13
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
ERN2 endoplasmic reticulum to nucleus signaling 2
FADS2 fatty acid desaturase 2
FLJ11710 uncharacterized protein FLJ11710
FRS2 fibroblast growth factor receptor substrate 2
FSTL3 follistatin-like 3 (secreted glycoprotein)
FUZ fuzzy planar cell polarity protein
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GATA4 GATA binding protein 4
GBP2 guanylate binding protein 2, interferon-inducible
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HIST1H2AL histone cluster 1, H2al
HIST1H2BM histone cluster 1, H2bm
HIST2H2AA3 histone cluster 2, H2aa3
HOXD11 homeobox D11
IDI2-AS1 IDI2 antisense RNA 1
IGSF1 immunoglobulin superfamily, member 1
INCENP inner centromere protein antigens 135/155kDa
IRF2BP1 interferon regulatory factor 2 binding protein 1
KIZ kizuna centrosomal protein
KLF2 Kruppel-like factor 2
KLHL26 kelch-like family member 26
LAMB3 laminin, beta 3
LARP6 La ribonucleoprotein domain family, member 6
LINS lines homolog (Drosophila)
LYZ lysozyme
MDM4 MDM4, p53 regulator
NACA2 nascent polypeptide-associated complex alpha subunit 2
NEK11 NIMA-related kinase 11
NIPAL2 NIPA-like domain containing 2
NLGN1 neuroligin 1
NOL12 nucleolar protein 12
NPM3 nucleophosmin/nucleoplasmin 3
OGFRL1 opioid growth factor receptor-like 1
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PIGH phosphatidylinositol glycan anchor biosynthesis, class H
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PITX2 paired-like homeodomain 2
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
PRR4 proline rich 4 (lacrimal)
PTPN14 protein tyrosine phosphatase, non-receptor type 14
QPCTL glutaminyl-peptide cyclotransferase-like
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RCAN3 RCAN family member 3
RGS20 regulator of G-protein signaling 20
SCAI suppressor of cancer cell invasion
SCGB2A2 secretoglobin, family 2A, member 2
SCN1B sodium channel, voltage gated, type I beta subunit
SDC3 syndecan 3
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SH2D4A SH2 domain containing 4A
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SRD5A3 steroid 5 alpha-reductase 3
STX1A syntaxin 1A (brain)
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TCTN1 tectonic family member 1
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TSPAN1 tetraspanin 1
TTC23 tetratricopeptide repeat domain 23
UBQLN4 ubiquilin 4
USB1 U6 snRNA biogenesis 1
VGF VGF nerve growth factor inducible
WLS wntless Wnt ligand secretion mediator
XYLT2 xylosyltransferase II
ZBTB22 zinc finger and BTB domain containing 22
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF134 zinc finger protein 134
ZNF212 zinc finger protein 212
ZNF665 zinc finger protein 665
ZNF778 zinc finger protein 778