sulfafurazole-5257 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the sulfafurazole-5257 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
AIPL1 aryl hydrocarbon receptor interacting protein-like 1
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ARHGAP4 Rho GTPase activating protein 4
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2
ATXN2L ataxin 2-like
BCL2 B-cell CLL/lymphoma 2
BMP1 bone morphogenetic protein 1
C21ORF2 chromosome 21 open reading frame 2
C3 complement component 3
CD300C CD300c molecule
CDC42 cell division cycle 42
CDO1 cysteine dioxygenase type 1
CEND1 cell cycle exit and neuronal differentiation 1
CLEC3B C-type lectin domain family 3, member B
COL13A1 collagen, type XIII, alpha 1
DBT dihydrolipoamide branched chain transacylase E2
DCSTAMP dendrocyte expressed seven transmembrane protein
DRD2 dopamine receptor D2
FAM120C family with sequence similarity 120C
FAT4 FAT atypical cadherin 4
FLJ11292
FLRT2 fibronectin leucine rich transmembrane protein 2
FN1 fibronectin 1
FRMD4B FERM domain containing 4B
FUT9 fucosyltransferase 9 (alpha (1,3) fucosyltransferase)
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HIST1H2AB histone cluster 1, H2ab
HLF hepatic leukemia factor
IFI35 interferon-induced protein 35
ING1 inhibitor of growth family, member 1
IPW imprinted in Prader-Willi syndrome (non-protein coding)
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNMB2 potassium channel subfamily M regulatory beta subunit 2
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KDM5B lysine (K)-specific demethylase 5B
KLHL29 kelch-like family member 29
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
KRT17 keratin 17, type I
KSR1 kinase suppressor of ras 1
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LINC01587 long intergenic non-protein coding RNA 1587
MAP1A microtubule-associated protein 1A
MAP2K5 mitogen-activated protein kinase kinase 5
MCF2 MCF.2 cell line derived transforming sequence
MET MET proto-oncogene, receptor tyrosine kinase
MXRA8 matrix-remodelling associated 8
NCOR2 nuclear receptor corepressor 2
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
NOX4 NADPH oxidase 4
ONECUT1 one cut homeobox 1
PADI3 peptidyl arginine deiminase, type III
PAPPA2 pappalysin 2
PART1 prostate androgen-regulated transcript 1 (non-protein coding)
PDE10A phosphodiesterase 10A
PDE7B phosphodiesterase 7B
PHF8 PHD finger protein 8
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PILRA paired immunoglobin-like type 2 receptor alpha
PPIAL4A peptidylprolyl isomerase A (cyclophilin A)-like 4A
PPP1R37 protein phosphatase 1, regulatory subunit 37
PRDM12 PR domain containing 12
PRKCB protein kinase C, beta
RASAL2 RAS protein activator like 2
RBM26 RNA binding motif protein 26
RHAG Rh-associated glycoprotein
RPL23AP53 ribosomal protein L23a pseudogene 53
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SCAND2P SCAN domain containing 2 pseudogene
SERHL2 serine hydrolase-like 2
SFTPD surfactant protein D
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SH2D3A SH2 domain containing 3A
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC39A9 solute carrier family 39, member 9
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SNCAIP synuclein, alpha interacting protein
SPAG8 sperm associated antigen 8
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
SRF serum response factor (c-fos serum response element-binding transcription factor)
SULT4A1 sulfotransferase family 4A, member 1
SZT2 seizure threshold 2 homolog (mouse)
TAGLN3 transgelin 3
TBX5 T-box 5
TDRD3 tudor domain containing 3
TECPR2 tectonin beta-propeller repeat containing 2
TGM2 transglutaminase 2
TRIM29 tripartite motif containing 29
UNC119 unc-119 homolog (C. elegans)
UPK3B uroplakin 3B
XIST X inactive specific transcript (non-protein coding)
ZER1 zyg-11 related, cell cycle regulator
ZMAT4 zinc finger, matrin-type 4
ZNF423 zinc finger protein 423

decreased expression

Symbol Name
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ASPHD1 aspartate beta-hydroxylase domain containing 1
C11ORF63 chromosome 11 open reading frame 63
C1ORF105 chromosome 1 open reading frame 105
C2ORF27A chromosome 2 open reading frame 27A
CAMK1 calcium/calmodulin-dependent protein kinase I
CAMK4 calcium/calmodulin-dependent protein kinase IV
CARF calcium responsive transcription factor
CDK20 cyclin-dependent kinase 20
CDK3 cyclin-dependent kinase 3
CEP85 centrosomal protein 85kDa
CIDEB cell death-inducing DFFA-like effector b
CIR1 corepressor interacting with RBPJ, 1
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CORT cortistatin
CXXC4 CXXC finger protein 4
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DGKD diacylglycerol kinase, delta 130kDa
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DNAAF2 dynein, axonemal, assembly factor 2
DPY19L1P1 DPY19L1 pseudogene 1
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
EPHX2 epoxide hydrolase 2, cytoplasmic
ETV6 ets variant 6
FER fer (fps/fes related) tyrosine kinase
FFAR2 free fatty acid receptor 2
FGF23 fibroblast growth factor 23
FSTL3 follistatin-like 3 (secreted glycoprotein)
GAMT guanidinoacetate N-methyltransferase
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GUSBP3 glucuronidase, beta pseudogene 3
HIST2H2AA3 histone cluster 2, H2aa3
HMOX1 heme oxygenase 1
HSPA1L heat shock 70kDa protein 1-like
IFI27 interferon, alpha-inducible protein 27
KIAA0319L KIAA0319-like
LMCD1 LIM and cysteine-rich domains 1
LOC390998 ribosomal protein L10 pseudogene
LRRC20 leucine rich repeat containing 20
MAST3 microtubule associated serine/threonine kinase 3
MBNL3 muscleblind-like splicing regulator 3
MFAP2 microfibrillar-associated protein 2
MTA2 metastasis associated 1 family, member 2
NEUROD4 neuronal differentiation 4
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NR1H2 nuclear receptor subfamily 1, group H, member 2
NRGN neurogranin (protein kinase C substrate, RC3)
NT5DC3 5'-nucleotidase domain containing 3
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
OR2B6 olfactory receptor, family 2, subfamily B, member 6
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PADI1 peptidyl arginine deiminase, type I
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PARD6A par-6 family cell polarity regulator alpha
PCDHB13 protocadherin beta 13
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PGR progesterone receptor
PPAP2C phosphatidic acid phosphatase type 2C
R3HCC1L R3H domain and coiled-coil containing 1-like
RAB30 RAB30, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
RIN1 Ras and Rab interactor 1
RNF39 ring finger protein 39
RPL10L ribosomal protein L10-like
S100A4 S100 calcium binding protein A4
S100A7 S100 calcium binding protein A7
SCGB2A2 secretoglobin, family 2A, member 2
SIRT6 sirtuin 6
SIX1 SIX homeobox 1
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLC35F5 solute carrier family 35, member F5
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SLPI secretory leukocyte peptidase inhibitor
TAOK1 TAO kinase 1
TCTN1 tectonic family member 1
THRAP3 thyroid hormone receptor associated protein 3
TLR5 toll-like receptor 5
TMEM120B transmembrane protein 120B
TMEM242 transmembrane protein 242
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
UBQLN4 ubiquilin 4
USP20 ubiquitin specific peptidase 20
VIPR1 vasoactive intestinal peptide receptor 1
WDR33 WD repeat domain 33
XYLT2 xylosyltransferase II
ZDHHC14 zinc finger, DHHC-type containing 14
ZFHX4 zinc finger homeobox 4
ZNF480 zinc finger protein 480
ZNF516 zinc finger protein 516
ZNF639 zinc finger protein 639
ZNF652 zinc finger protein 652