sulfafurazole-5622 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the sulfafurazole-5622 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ACPP acid phosphatase, prostate
ADM adrenomedullin
ALS2CL ALS2 C-terminal like
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
ARSD arylsulfatase D
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2
B9D2 B9 protein domain 2
C1QL1 complement component 1, q subcomponent-like 1
C9ORF9 chromosome 9 open reading frame 9
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCDC57 coiled-coil domain containing 57
CD4 CD4 molecule
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CFAP69 cilia and flagella associated protein 69
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle)
COL4A6 collagen, type IV, alpha 6
CTSO cathepsin O
CXCR2 chemokine (C-X-C motif) receptor 2
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DEFA4 defensin, alpha 4, corticostatin
DPF1 D4, zinc and double PHD fingers family 1
DPF3 D4, zinc and double PHD fingers, family 3
ECM2 extracellular matrix protein 2, female organ and adipocyte specific
EPHA5 EPH receptor A5
FBXO41 F-box protein 41
FGF1 fibroblast growth factor 1 (acidic)
FRMD8 FERM domain containing 8
FUT9 fucosyltransferase 9 (alpha (1,3) fucosyltransferase)
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GIF gastric intrinsic factor (vitamin B synthesis)
GOLGA8A golgin A8 family, member A
GPR153 G protein-coupled receptor 153
GREB1L growth regulation by estrogen in breast cancer-like
GRM1 glutamate receptor, metabotropic 1
HNF4A hepatocyte nuclear factor 4, alpha
HR hair growth associated
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
IFFO1 intermediate filament family orphan 1
IFT54 intraflagellar transport 54
JPH3 junctophilin 3
KCNK2 potassium channel, two pore domain subfamily K, member 2
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KHSRP KH-type splicing regulatory protein
KIAA1644 KIAA1644
KLHL29 kelch-like family member 29
KRT23 keratin 23, type I
LAMP1 lysosomal-associated membrane protein 1
LEFTY2 left-right determination factor 2
LIMCH1 LIM and calponin homology domains 1
LMTK1 lemur tail kinase 1
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
LY6G6C lymphocyte antigen 6 complex, locus G6C
MAN1A2 mannosidase, alpha, class 1A, member 2
MBD3 methyl-CpG binding domain protein 3
MYO3A myosin IIIA
NEK9 NIMA-related kinase 9
NOTCH3 notch 3
PDE4C phosphodiesterase 4C, cAMP-specific
PLLP plasmolipin
POU1F1 POU class 1 homeobox 1
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PRM1 protamine 1
PTAFR platelet-activating factor receptor
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTPRS protein tyrosine phosphatase, receptor type, S
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RUNX1 runt-related transcription factor 1
SETBP1 SET binding protein 1
SFRP4 secreted frizzled-related protein 4
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SH3BP2 SH3-domain binding protein 2
SHOX2 short stature homeobox 2
SLA Src-like-adaptor
SOHLH2 spermatogenesis and oogenesis specific basic helix-loop-helix 2
SPON2 spondin 2, extracellular matrix protein
SYNDIG1 synapse differentiation inducing 1
TARP TCR gamma alternate reading frame protein
TFDP3 transcription factor Dp family, member 3
TLR1 toll-like receptor 1
TM4SF1 transmembrane 4 L six family member 1
TM4SF4 transmembrane 4 L six family member 4
TMEM63A transmembrane protein 63A
TMPRSS6 transmembrane protease, serine 6
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TUBA3C tubulin, alpha 3c
WDR55 WD repeat domain 55
WDR62 WD repeat domain 62
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF277 zinc finger protein 277
ZNF419 zinc finger protein 419
ZNF532 zinc finger protein 532
ZNF76 zinc finger protein 76
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ABI3BP ABI family, member 3 (NESH) binding protein
ACTG2 actin, gamma 2, smooth muscle, enteric
ADCY7 adenylate cyclase 7
AFAP1 actin filament associated protein 1
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BAHD1 bromo adjacent homology domain containing 1
BFSP1 beaded filament structural protein 1, filensin
C14ORF93 chromosome 14 open reading frame 93
C1ORF159 chromosome 1 open reading frame 159
C2ORF27A chromosome 2 open reading frame 27A
CA11 carbonic anhydrase XI
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CDK3 cyclin-dependent kinase 3
CEMIP cell migration inducing protein, hyaluronan binding
CORT cortistatin
CRELD1 cysteine-rich with EGF-like domains 1
CRIP1 cysteine-rich protein 1 (intestinal)
CSTA cystatin A (stefin A)
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
DUSP2 dual specificity phosphatase 2
DYSF dysferlin
ERN2 endoplasmic reticulum to nucleus signaling 2
ETV6 ets variant 6
FAM110B family with sequence similarity 110, member B
FAM120C family with sequence similarity 120C
FAM131A family with sequence similarity 131, member A
FFAR2 free fatty acid receptor 2
FGD1 FYVE, RhoGEF and PH domain containing 1
FGF23 fibroblast growth factor 23
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GAMT guanidinoacetate N-methyltransferase
GFI1 growth factor independent 1 transcription repressor
GJA8 gap junction protein, alpha 8, 50kDa
GMPR guanosine monophosphate reductase
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GPR27 G protein-coupled receptor 27
GPX2 glutathione peroxidase 2
GRPR gastrin-releasing peptide receptor
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H2AI histone cluster 1, H2ai
HIST1H2BC histone cluster 1, H2bc
HOXB2 homeobox B2
HOXC4 homeobox C4
IL2 interleukin 2
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KDM7A lysine (K)-specific demethylase 7A
KIF16B kinesin family member 16B
LINC00597 long intergenic non-protein coding RNA 597
LMO2 LIM domain only 2 (rhombotin-like 1)
LRRC61 leucine rich repeat containing 61
MAL mal, T-cell differentiation protein
MAST3 microtubule associated serine/threonine kinase 3
MCC mutated in colorectal cancers
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
NACA2 nascent polypeptide-associated complex alpha subunit 2
NCALD neurocalcin delta
NLRX1 NLR family member X1
NPTX1 neuronal pentraxin I
NT5E 5'-nucleotidase, ecto (CD73)
PDE8B phosphodiesterase 8B
PLD2 phospholipase D2
PRPH peripherin
PRSS53 protease, serine, 53
QPCTL glutaminyl-peptide cyclotransferase-like
RFXAP regulatory factor X-associated protein
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RPL23AP32 ribosomal protein L23a pseudogene 32
RRAGB Ras-related GTP binding B
SENP7 SUMO1/sentrin specific peptidase 7
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SP140L SP140 nuclear body protein-like
STX1A syntaxin 1A (brain)
SULT4A1 sulfotransferase family 4A, member 1
SYNC syncoilin, intermediate filament protein
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TGFBR1 transforming growth factor, beta receptor 1
TMEM242 transmembrane protein 242
TMEM45A transmembrane protein 45A
TMEM53 transmembrane protein 53
TPST2 tyrosylprotein sulfotransferase 2
TTLL1 tubulin tyrosine ligase-like family member 1
USP27X ubiquitin specific peptidase 27, X-linked
YEATS4 YEATS domain containing 4
ZNF350 zinc finger protein 350
ZNF442 zinc finger protein 442
ZNF484 zinc finger protein 484
ZNF711 zinc finger protein 711
ZNF747 zinc finger protein 747
ZW10 zw10 kinetochore protein