| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the sulfafurazole-5622 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAGAB | alpha- and gamma-adaptin binding protein |
| ACPP | acid phosphatase, prostate |
| ADM | adrenomedullin |
| ALS2CL | ALS2 C-terminal like |
| APOBEC2 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 |
| ARSD | arylsulfatase D |
| ATP8A2 | ATPase, aminophospholipid transporter, class I, type 8A, member 2 |
| B9D2 | B9 protein domain 2 |
| C1QL1 | complement component 1, q subcomponent-like 1 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CCDC57 | coiled-coil domain containing 57 |
| CD4 | CD4 molecule |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CFAP69 | cilia and flagella associated protein 69 |
| CHRNA1 | cholinergic receptor, nicotinic, alpha 1 (muscle) |
| COL4A6 | collagen, type IV, alpha 6 |
| CTSO | cathepsin O |
| CXCR2 | chemokine (C-X-C motif) receptor 2 |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 |
| DEFA4 | defensin, alpha 4, corticostatin |
| DPF1 | D4, zinc and double PHD fingers family 1 |
| DPF3 | D4, zinc and double PHD fingers, family 3 |
| ECM2 | extracellular matrix protein 2, female organ and adipocyte specific |
| EPHA5 | EPH receptor A5 |
| FBXO41 | F-box protein 41 |
| FGF1 | fibroblast growth factor 1 (acidic) |
| FRMD8 | FERM domain containing 8 |
| FUT9 | fucosyltransferase 9 (alpha (1,3) fucosyltransferase) |
| GGA1 | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 |
| GIF | gastric intrinsic factor (vitamin B synthesis) |
| GOLGA8A | golgin A8 family, member A |
| GPR153 | G protein-coupled receptor 153 |
| GREB1L | growth regulation by estrogen in breast cancer-like |
| GRM1 | glutamate receptor, metabotropic 1 |
| HNF4A | hepatocyte nuclear factor 4, alpha |
| HR | hair growth associated |
| HTR2B | 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase |
| IFFO1 | intermediate filament family orphan 1 |
| IFT54 | intraflagellar transport 54 |
| JPH3 | junctophilin 3 |
| KCNK2 | potassium channel, two pore domain subfamily K, member 2 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KHSRP | KH-type splicing regulatory protein |
| KIAA1644 | KIAA1644 |
| KLHL29 | kelch-like family member 29 |
| KRT23 | keratin 23, type I |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LEFTY2 | left-right determination factor 2 |
| LIMCH1 | LIM and calponin homology domains 1 |
| LMTK1 | lemur tail kinase 1 |
| LRCH4 | leucine-rich repeats and calponin homology (CH) domain containing 4 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 |
| MBD3 | methyl-CpG binding domain protein 3 |
| MYO3A | myosin IIIA |
| NEK9 | NIMA-related kinase 9 |
| NOTCH3 | notch 3 |
| PDE4C | phosphodiesterase 4C, cAMP-specific |
| PLLP | plasmolipin |
| POU1F1 | POU class 1 homeobox 1 |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) |
| PRM1 | protamine 1 |
| PTAFR | platelet-activating factor receptor |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| PTPRS | protein tyrosine phosphatase, receptor type, S |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 |
| RUNX1 | runt-related transcription factor 1 |
| SETBP1 | SET binding protein 1 |
| SFRP4 | secreted frizzled-related protein 4 |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
| SH3BP2 | SH3-domain binding protein 2 |
| SHOX2 | short stature homeobox 2 |
| SLA | Src-like-adaptor |
| SOHLH2 | spermatogenesis and oogenesis specific basic helix-loop-helix 2 |
| SPON2 | spondin 2, extracellular matrix protein |
| SYNDIG1 | synapse differentiation inducing 1 |
| TARP | TCR gamma alternate reading frame protein |
| TFDP3 | transcription factor Dp family, member 3 |
| TLR1 | toll-like receptor 1 |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TM4SF4 | transmembrane 4 L six family member 4 |
| TMEM63A | transmembrane protein 63A |
| TMPRSS6 | transmembrane protease, serine 6 |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TUBA3C | tubulin, alpha 3c |
| WDR55 | WD repeat domain 55 |
| WDR62 | WD repeat domain 62 |
| XRCC4 | X-ray repair complementing defective repair in Chinese hamster cells 4 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZNF277 | zinc finger protein 277 |
| ZNF419 | zinc finger protein 419 |
| ZNF532 | zinc finger protein 532 |
| ZNF76 | zinc finger protein 76 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
| Symbol | Name |
|---|---|
| ABI3BP | ABI family, member 3 (NESH) binding protein |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ADCY7 | adenylate cyclase 7 |
| AFAP1 | actin filament associated protein 1 |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| BFSP1 | beaded filament structural protein 1, filensin |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| CA11 | carbonic anhydrase XI |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CDK3 | cyclin-dependent kinase 3 |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CORT | cortistatin |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CSTA | cystatin A (stefin A) |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DUSP2 | dual specificity phosphatase 2 |
| DYSF | dysferlin |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| ETV6 | ets variant 6 |
| FAM110B | family with sequence similarity 110, member B |
| FAM120C | family with sequence similarity 120C |
| FAM131A | family with sequence similarity 131, member A |
| FFAR2 | free fatty acid receptor 2 |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FGF23 | fibroblast growth factor 23 |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GAMT | guanidinoacetate N-methyltransferase |
| GFI1 | growth factor independent 1 transcription repressor |
| GJA8 | gap junction protein, alpha 8, 50kDa |
| GMPR | guanosine monophosphate reductase |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| GPR27 | G protein-coupled receptor 27 |
| GPX2 | glutathione peroxidase 2 |
| GRPR | gastrin-releasing peptide receptor |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H2BC | histone cluster 1, H2bc |
| HOXB2 | homeobox B2 |
| HOXC4 | homeobox C4 |
| IL2 | interleukin 2 |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| KDM7A | lysine (K)-specific demethylase 7A |
| KIF16B | kinesin family member 16B |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| LRRC61 | leucine rich repeat containing 61 |
| MAL | mal, T-cell differentiation protein |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MCC | mutated in colorectal cancers |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NCALD | neurocalcin delta |
| NLRX1 | NLR family member X1 |
| NPTX1 | neuronal pentraxin I |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| PDE8B | phosphodiesterase 8B |
| PLD2 | phospholipase D2 |
| PRPH | peripherin |
| PRSS53 | protease, serine, 53 |
| QPCTL | glutaminyl-peptide cyclotransferase-like |
| RFXAP | regulatory factor X-associated protein |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RRAGB | Ras-related GTP binding B |
| SENP7 | SUMO1/sentrin specific peptidase 7 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SP140L | SP140 nuclear body protein-like |
| STX1A | syntaxin 1A (brain) |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| SYNC | syncoilin, intermediate filament protein |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TGFBR1 | transforming growth factor, beta receptor 1 |
| TMEM242 | transmembrane protein 242 |
| TMEM45A | transmembrane protein 45A |
| TMEM53 | transmembrane protein 53 |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| YEATS4 | YEATS domain containing 4 |
| ZNF350 | zinc finger protein 350 |
| ZNF442 | zinc finger protein 442 |
| ZNF484 | zinc finger protein 484 |
| ZNF711 | zinc finger protein 711 |
| ZNF747 | zinc finger protein 747 |
| ZW10 | zw10 kinetochore protein |