sulfaguanidine-1495 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the sulfaguanidine-1495 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADCY7 adenylate cyclase 7
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALPK1 alpha-kinase 1
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ASPH aspartate beta-hydroxylase
BCAS1 breast carcinoma amplified sequence 1
CD80 CD80 molecule
CD82 CD82 molecule
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CEP104 centrosomal protein 104kDa
CLEC3B C-type lectin domain family 3, member B
COL5A2 collagen, type V, alpha 2
CYSLTR2 cysteinyl leukotriene receptor 2
DAPK3 death-associated protein kinase 3
DLC1 DLC1 Rho GTPase activating protein
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DOHH deoxyhypusine hydroxylase/monooxygenase
ENGASE endo-beta-N-acetylglucosaminidase
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
EPHX2 epoxide hydrolase 2, cytoplasmic
ERC1 ELKS/RAB6-interacting/CAST family member 1
ERN2 endoplasmic reticulum to nucleus signaling 2
EXTL3 exostosin-like glycosyltransferase 3
F3 coagulation factor III (thromboplastin, tissue factor)
FBLN1 fibulin 1
FBXO2 F-box protein 2
FBXO9 F-box protein 9
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GPC1 glypican 1
GPR21 G protein-coupled receptor 21
GUSBP3 glucuronidase, beta pseudogene 3
HBEGF heparin-binding EGF-like growth factor
HDAC7 histone deacetylase 7
HFE hemochromatosis
HMGN5 high mobility group nucleosome binding domain 5
HOMER3 homer scaffolding protein 3
HOXC10 homeobox C10
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KLF9 Kruppel-like factor 9
LAMB1 laminin, beta 1
LINC00115 long intergenic non-protein coding RNA 115
LOC729164 hCG1732469
LRRC14 leucine rich repeat containing 14
MAPK8 mitogen-activated protein kinase 8
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MST1L macrophage stimulating 1-like
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NF2 neurofibromin 2 (merlin)
NNAT neuronatin
NUMA1 nuclear mitotic apparatus protein 1
PGAP1 post-GPI attachment to proteins 1
PHF20L1 PHD finger protein 20-like 1
PIDD1 p53-induced death domain protein 1
PKNOX1 PBX/knotted 1 homeobox 1
PKNOX2 PBX/knotted 1 homeobox 2
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLK3 polo-like kinase 3
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PRDX2 peroxiredoxin 2
PRODH proline dehydrogenase (oxidase) 1
PRSS53 protease, serine, 53
PTCRA pre T-cell antigen receptor alpha
PTPN14 protein tyrosine phosphatase, non-receptor type 14
RAB2A RAB2A, member RAS oncogene family
RAB6A RAB6A, member RAS oncogene family
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RBPMS RNA binding protein with multiple splicing
REC8 REC8 meiotic recombination protein
RHBG Rh family, B glycoprotein (gene/pseudogene)
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RPS28 ribosomal protein S28
RTEL1 regulator of telomere elongation helicase 1
SCD5 stearoyl-CoA desaturase 5
SCG2 secretogranin II
SDC2 syndecan 2
SETD1A SET domain containing 1A
SIK3 SIK family kinase 3
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium)
SPDEF SAM pointed domain containing ETS transcription factor
SPG20 spastic paraplegia 20 (Troyer syndrome)
SPHK2 sphingosine kinase 2
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
TCF3 transcription factor 3
TCHH trichohyalin
TGM2 transglutaminase 2
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TMC7 transmembrane channel-like 7
TPMT thiopurine S-methyltransferase
TRD T cell receptor delta locus
TTC38 tetratricopeptide repeat domain 38
YIPF4 Yip1 domain family, member 4
ZBTB33 zinc finger and BTB domain containing 33
ZNF573 zinc finger protein 573

decreased expression

Symbol Name
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARRB1 arrestin, beta 1
ASPHD1 aspartate beta-hydroxylase domain containing 1
BRD9 bromodomain containing 9
C1ORF159 chromosome 1 open reading frame 159
CAMK1 calcium/calmodulin-dependent protein kinase I
CAPG capping protein (actin filament), gelsolin-like
CCDC92 coiled-coil domain containing 92
CENPQ centromere protein Q
CEP170B centrosomal protein 170B
CEP85 centrosomal protein 85kDa
CFD complement factor D (adipsin)
CHKB choline kinase beta
CHML choroideremia-like (Rab escort protein 2)
CLCN6 chloride channel, voltage-sensitive 6
CORO2A coronin, actin binding protein, 2A
DGKD diacylglycerol kinase, delta 130kDa
DOC2A double C2-like domains, alpha
DUSP2 dual specificity phosphatase 2
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EFTUD1 elongation factor Tu GTP binding domain containing 1
EGLN3 egl-9 family hypoxia-inducible factor 3
EPHA2 EPH receptor A2
EPPK1 epiplakin 1
ERCC4 excision repair cross-complementation group 4
FAM188A family with sequence similarity 188, member A
FBXO31 F-box protein 31
GAMT guanidinoacetate N-methyltransferase
GCHFR GTP cyclohydrolase I feedback regulator
GID4 GID complex subunit 4
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPATCH2L G patch domain containing 2-like
GRTP1 growth hormone regulated TBC protein 1
HIST1H2AI histone cluster 1, H2ai
HIST1H2AM histone cluster 1, H2am
HP1BP3 heterochromatin protein 1, binding protein 3
HSPA1L heat shock 70kDa protein 1-like
HSPA2 heat shock 70kDa protein 2
HYAL2 hyaluronoglucosaminidase 2
IL15RA interleukin 15 receptor, alpha
IRF1 interferon regulatory factor 1
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KIAA0355 KIAA0355
KLHL25 kelch-like family member 25
KLHL26 kelch-like family member 26
LIG4 ligase IV, DNA, ATP-dependent
LIN7A lin-7 homolog A (C. elegans)
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2
LRP2 low density lipoprotein receptor-related protein 2
MBOAT2 membrane bound O-acyltransferase domain containing 2
MCOLN3 mucolipin 3
MEIS1 Meis homeobox 1
MID1IP1 MID1 interacting protein 1
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
NDE1 nudE neurodevelopment protein 1
OSMR oncostatin M receptor
PC pyruvate carboxylase
PEX26 peroxisomal biogenesis factor 26
PLA2G10 phospholipase A2, group X
PLEKHA6 pleckstrin homology domain containing, family A member 6
PMCH pro-melanin-concentrating hormone
PRR14L proline rich 14-like
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF121 ring finger protein 121
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SH2D4A SH2 domain containing 4A
SH3BGR SH3 domain binding glutamate-rich protein
SIX1 SIX homeobox 1
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SLC22A14 solute carrier family 22, member 14
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC38A10 solute carrier family 38, member 10
SLMO1 slowmo homolog 1 (Drosophila)
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
STARD3 StAR-related lipid transfer (START) domain containing 3
STARD5 StAR-related lipid transfer (START) domain containing 5
TDRD1 tudor domain containing 1
TOE1 target of EGR1, member 1 (nuclear)
TRAIP TRAF interacting protein
TTC33 tetratricopeptide repeat domain 33
VEGFB vascular endothelial growth factor B
VEGFC vascular endothelial growth factor C
WDR4 WD repeat domain 4
YBX2 Y box binding protein 2
ZBED1 zinc finger, BED-type containing 1
ZBTB48 zinc finger and BTB domain containing 48
ZDHHC13 zinc finger, DHHC-type containing 13
ZNF16 zinc finger protein 16
ZNF211 zinc finger protein 211
ZNF350 zinc finger protein 350
ZNF423 zinc finger protein 423
ZNF510 zinc finger protein 510