sulfaguanidine-1913 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the sulfaguanidine-1913 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAK1 AP2 associated kinase 1
ACAN aggrecan
AEN apoptosis enhancing nuclease
AK1 adenylate kinase 1
AMT aminomethyltransferase
APOC1 apolipoprotein C-I
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ASIC1 acid sensing (proton gated) ion channel 1
ATG13 autophagy related 13
ATXN7L3B ataxin 7-like 3B
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
C17ORF70 chromosome 17 open reading frame 70
CCPG1 cell cycle progression 1
CD8A CD8a molecule
CIDEC cell death-inducing DFFA-like effector c
CPE carboxypeptidase E
CPT2 carnitine palmitoyltransferase 2
CSN2 casein beta
CYTH1 cytohesin 1
CYTH4 cytohesin 4
EGFL7 EGF-like-domain, multiple 7
EGLN2 egl-9 family hypoxia-inducible factor 2
ENOSF1 enolase superfamily member 1
FAM188A family with sequence similarity 188, member A
FER fer (fps/fes related) tyrosine kinase
FGFR1 fibroblast growth factor receptor 1
FOXO1 forkhead box O1
FZD8 frizzled class receptor 8
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GDF11 growth differentiation factor 11
GIMAP5 GTPase, IMAP family member 5
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
HEG1 heart development protein with EGF-like domains 1
HFE hemochromatosis
IGKV1D-13 immunoglobulin kappa variable 1D-13
ING4 inhibitor of growth family, member 4
IQCK IQ motif containing K
IVD isovaleryl-CoA dehydrogenase
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KIF25-AS1 KIF25 antisense RNA 1
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KRIT1 KRIT1, ankyrin repeat containing
KRT38 keratin 38, type I
L2HGDH L-2-hydroxyglutarate dehydrogenase
LDAH lipid droplet associated hydrolase
LHX2 LIM homeobox 2
LIAS lipoic acid synthetase
MAN1C1 mannosidase, alpha, class 1C, member 1
MECP2 methyl CpG binding protein 2
METRN meteorin, glial cell differentiation regulator
METTL5 methyltransferase like 5
MICALL1 MICAL-like 1
MXD4 MAX dimerization protein 4
MYO9B myosin IXB
NPPA natriuretic peptide A
NXT2 nuclear transport factor 2-like export factor 2
OLFM1 olfactomedin 1
P2RX6 purinergic receptor P2X, ligand gated ion channel, 6
PCSK7 proprotein convertase subtilisin/kexin type 7
PDK3 pyruvate dehydrogenase kinase, isozyme 3
PHF8 PHD finger protein 8
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PNISR PNN-interacting serine/arginine-rich protein
POLM polymerase (DNA directed), mu
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H
PTDSS2 phosphatidylserine synthase 2
RARA retinoic acid receptor, alpha
RECQL5 RecQ protein-like 5
RNF41 ring finger protein 41, E3 ubiquitin protein ligase
RNFT1 ring finger protein, transmembrane 1
RPUSD2 RNA pseudouridylate synthase domain containing 2
RTEL1 regulator of telomere elongation helicase 1
SAMHD1 SAM domain and HD domain 1
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SEZ6L seizure related 6 homolog (mouse)-like
SFSWAP splicing factor, suppressor of white-apricot family
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC22A18 solute carrier family 22, member 18
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SMG5 SMG5 nonsense mediated mRNA decay factor
SMG7 SMG7 nonsense mediated mRNA decay factor
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TMEM57 transmembrane protein 57
TOLLIP toll interacting protein
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
UBE3A ubiquitin protein ligase E3A
USF2 upstream transcription factor 2, c-fos interacting
USP2 ubiquitin specific peptidase 2
VAC14 Vac14 homolog (S. cerevisiae)
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
WASL Wiskott-Aldrich syndrome-like
WDR46 WD repeat domain 46
ZNF518A zinc finger protein 518A
ZNF710 zinc finger protein 710

decreased expression

Symbol Name
ACVR2B activin A receptor, type IIB
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ASAP1-IT1 ASAP1 intronic transcript 1
BAK1 BCL2-antagonist/killer 1
BARD1 BRCA1 associated RING domain 1
BMS1 BMS1 ribosome biogenesis factor
C19ORF24 chromosome 19 open reading frame 24
C1ORF35 chromosome 1 open reading frame 35
C2ORF44 chromosome 2 open reading frame 44
CAMK1 calcium/calmodulin-dependent protein kinase I
CAMTA2 calmodulin binding transcription activator 2
CHEK2 checkpoint kinase 2
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
CPSF3L cleavage and polyadenylation specific factor 3-like
CS citrate synthase
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2
CTAGE9 CTAGE family, member 9
CYB5R4 cytochrome b5 reductase 4
DDIT4 DNA-damage-inducible transcript 4
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DMTN dematin actin binding protein
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13
DSN1 DSN1, MIS12 kinetochore complex component
ERCC2 excision repair cross-complementation group 2
ERCC3 excision repair cross-complementation group 3
EVL Enah/Vasp-like
EVPL envoplakin
FBXL2 F-box and leucine-rich repeat protein 2
FEM1C fem-1 homolog c (C. elegans)
FOXJ2 forkhead box J2
GPR27 G protein-coupled receptor 27
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
HINFP histone H4 transcription factor
HLA-DMB major histocompatibility complex, class II, DM beta
HOXB13 homeobox B13
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IMP3 IMP3, U3 small nucleolar ribonucleoprotein
INO80D INO80 complex subunit D
INTS12 integrator complex subunit 12
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
KAT2B K(lysine) acetyltransferase 2B
KIF20B kinesin family member 20B
KIFC1 kinesin family member C1
KLHL2 kelch-like family member 2
KLHL26 kelch-like family member 26
KRT75 keratin 75, type II
KRT86 keratin 86, type II
LMBR1L limb development membrane protein 1-like
LMTK1 lemur tail kinase 1
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3
LRRC37A2 leucine rich repeat containing 37, member A2
LYPD1 LY6/PLAUR domain containing 1
MAGEF1 melanoma antigen family F1
MANSC1 MANSC domain containing 1
MFSD12 major facilitator superfamily domain containing 12
MGA MGA, MAX dimerization protein
MPHOSPH8 M-phase phosphoprotein 8
MTG1 mitochondrial ribosome-associated GTPase 1
NAP1L2 nucleosome assembly protein 1-like 2
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OGFRL1 opioid growth factor receptor-like 1
OSTM1 osteopetrosis associated transmembrane protein 1
PADI1 peptidyl arginine deiminase, type I
PARG poly (ADP-ribose) glycohydrolase
PARP6 poly (ADP-ribose) polymerase family, member 6
PIGA phosphatidylinositol glycan anchor biosynthesis, class A
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PPP1R13B protein phosphatase 1, regulatory subunit 13B
PROS1 protein S (alpha)
PSAT1 phosphoserine aminotransferase 1
RBM38 RNA binding motif protein 38
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RNF167 ring finger protein 167
RNF220 ring finger protein 220
ROGDI rogdi homolog (Drosophila)
RPL23AP32 ribosomal protein L23a pseudogene 32
SALL2 spalt-like transcription factor 2
SETD3 SET domain containing 3
SEZ6L2 seizure related 6 homolog (mouse)-like 2
SH2B3 SH2B adaptor protein 3
SHROOM2 shroom family member 2
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SNTA1 syntrophin, alpha 1
STRN4 striatin, calmodulin binding protein 4
TAOK1 TAO kinase 1
TICAM1 toll-like receptor adaptor molecule 1
TMEM184B transmembrane protein 184B
TUBA3C tubulin, alpha 3c
TULP4 tubby like protein 4
UEVLD UEV and lactate/malate dehyrogenase domains
ZIM2 zinc finger, imprinted 2
ZNF175 zinc finger protein 175
ZNF189 zinc finger protein 189
ZNF239 zinc finger protein 239
ZNHIT2 zinc finger, HIT-type containing 2