sulfaguanidine-1995 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the sulfaguanidine-1995 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAA2 acetyl-CoA acyltransferase 2
ACOT7 acyl-CoA thioesterase 7
AKT3 v-akt murine thymoma viral oncogene homolog 3
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
ARNT aryl hydrocarbon receptor nuclear translocator
ASIC1 acid sensing (proton gated) ion channel 1
ATM ATM serine/threonine kinase
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1
BBIP1 BBSome interacting protein 1
CCPG1 cell cycle progression 1
CENPT centromere protein T
CETN1 centrin, EF-hand protein, 1
CLP1 cleavage and polyadenylation factor I subunit 1
CNTNAP1 contactin associated protein 1
CTSZ cathepsin Z
CYB561 cytochrome b561
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DERL2 derlin 2
DGCR8 DGCR8 microprocessor complex subunit
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DUSP2 dual specificity phosphatase 2
EGLN1 egl-9 family hypoxia-inducible factor 1
EHMT2 euchromatic histone-lysine N-methyltransferase 2
ENOX2 ecto-NOX disulfide-thiol exchanger 2
FAM188A family with sequence similarity 188, member A
FAM53B family with sequence similarity 53, member B
FAM65A family with sequence similarity 65, member A
FBXW11 F-box and WD repeat domain containing 11
GFOD2 glucose-fructose oxidoreductase domain containing 2
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GRK5 G protein-coupled receptor kinase 5
GSAP gamma-secretase activating protein
GTPBP4 GTP binding protein 4
HIRA histone cell cycle regulator
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HMMR hyaluronan-mediated motility receptor (RHAMM)
HOOK2 hook microtubule-tethering protein 2
ICA1 islet cell autoantigen 1, 69kDa
IGF1R insulin-like growth factor 1 receptor
IGSF6 immunoglobulin superfamily, member 6
IL2RB interleukin 2 receptor, beta
IVD isovaleryl-CoA dehydrogenase
KAT2B K(lysine) acetyltransferase 2B
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIF20B kinesin family member 20B
LENEP lens epithelial protein
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
MAGED2 melanoma antigen family D2
MAN1B1 mannosidase, alpha, class 1B, member 1
MPHOSPH9 M-phase phosphoprotein 9
MST1 macrophage stimulating 1
MTAP methylthioadenosine phosphorylase
MTERF1 mitochondrial transcription termination factor 1
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MUTYH mutY homolog
MX1 MX dynamin-like GTPase 1
N4BP1 NEDD4 binding protein 1
N4BP2L2 NEDD4 binding protein 2-like 2
NAA35 N(alpha)-acetyltransferase 35, NatC auxiliary subunit
NCOA3 nuclear receptor coactivator 3
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NEIL3 nei endonuclease VIII-like 3 (E. coli)
NPM3 nucleophosmin/nucleoplasmin 3
NUBP2 nucleotide binding protein 2
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
OVGP1 oviductal glycoprotein 1, 120kDa
PAQR3 progestin and adipoQ receptor family member III
PDCL phosducin-like
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PKP4 plakophilin 4
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
PRMT2 protein arginine methyltransferase 2
PVR poliovirus receptor
QTRT1 queuine tRNA-ribosyltransferase 1
RAB7A RAB7A, member RAS oncogene family
RABGGTB Rab geranylgeranyltransferase, beta subunit
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RBM47 RNA binding motif protein 47
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
RECK reversion-inducing-cysteine-rich protein with kazal motifs
RPL38 ribosomal protein L38
SCYL3 SCY1-like 3 (S. cerevisiae)
SECISBP2L SECIS binding protein 2-like
SLC25A44 solute carrier family 25, member 44
SMAD6 SMAD family member 6
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SNHG20 small nucleolar RNA host gene 20
SUMO1 small ubiquitin-like modifier 1
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TMBIM1 transmembrane BAX inhibitor motif containing 1
TMEM38B transmembrane protein 38B
TRIM14 tripartite motif containing 14
USP12 ubiquitin specific peptidase 12
VDAC3 voltage-dependent anion channel 3
VEZF1 vascular endothelial zinc finger 1
YIPF6 Yip1 domain family, member 6
ZMYM2 zinc finger, MYM-type 2
ZNF267 zinc finger protein 267
ZNF410 zinc finger protein 410

decreased expression

Symbol Name
ACIN1 apoptotic chromatin condensation inducer 1
ACO1 aconitase 1, soluble
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
APH1B APH1B gamma secretase subunit
ARHGAP4 Rho GTPase activating protein 4
ARID4A AT rich interactive domain 4A (RBP1-like)
BLVRB biliverdin reductase B
C12ORF49 chromosome 12 open reading frame 49
C4ORF29 chromosome 4 open reading frame 29
C7ORF43 chromosome 7 open reading frame 43
CAPG capping protein (actin filament), gelsolin-like
CCL2 chemokine (C-C motif) ligand 2
CD151 CD151 molecule (Raph blood group)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEP170B centrosomal protein 170B
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
CPSF3L cleavage and polyadenylation specific factor 3-like
DAO D-amino-acid oxidase
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7
DSN1 DSN1, MIS12 kinetochore complex component
ECSIT ECSIT signalling integrator
EDC4 enhancer of mRNA decapping 4
FAM168B family with sequence similarity 168, member B
FAM63A family with sequence similarity 63, member A
FBXW4 F-box and WD repeat domain containing 4
FGF4 fibroblast growth factor 4
GPNMB glycoprotein (transmembrane) nmb
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HIST3H2A histone cluster 3, H2a
IGFLR1 IGF-like family receptor 1
IMP3 IMP3, U3 small nucleolar ribonucleoprotein
INO80D INO80 complex subunit D
ITFG1 integrin alpha FG-GAP repeat containing 1
ITM2C integral membrane protein 2C
KIZ kizuna centrosomal protein
KRI1 KRI1 homolog (S. cerevisiae)
LONRF3 LON peptidase N-terminal domain and ring finger 3
LRRC37A3 leucine rich repeat containing 37, member A3
MAN2B2 mannosidase, alpha, class 2B, member 2
MCC mutated in colorectal cancers
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MPST mercaptopyruvate sulfurtransferase
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
MTMR11 myotubularin related protein 11
MYO9A myosin IXA
NABP2 nucleic acid binding protein 2
NCKAP1L NCK-associated protein 1-like
NDRG1 N-myc downstream regulated 1
NVL nuclear VCP-like
ORAI3 ORAI calcium release-activated calcium modulator 3
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
PCNXL4 pecanex-like 4 (Drosophila)
PCSK7 proprotein convertase subtilisin/kexin type 7
PHACTR4 phosphatase and actin regulator 4
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PMVK phosphomevalonate kinase
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G
PRPF38B pre-mRNA processing factor 38B
PRR14L proline rich 14-like
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
RAB4B RAB4B, member RAS oncogene family
RANBP10 RAN binding protein 10
RBBP5 retinoblastoma binding protein 5
RPL23AP32 ribosomal protein L23a pseudogene 32
SCN10A sodium channel, voltage gated, type X alpha subunit
SEC24C SEC24 family member C
SFMBT1 Scm-like with four mbt domains 1
SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1
STK25 serine/threonine kinase 25
STYXL1 serine/threonine/tyrosine interacting-like 1
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TEX40 testis expressed 40
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TM7SF2 transmembrane 7 superfamily member 2
TMED1 transmembrane emp24 protein transport domain containing 1
TRAC T cell receptor alpha constant
TRMT1L tRNA methyltransferase 1 homolog (S. cerevisiae)-like
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
UBP1 upstream binding protein 1 (LBP-1a)
UBQLN4 ubiquilin 4
UNC93B1 unc-93 homolog B1 (C. elegans)
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WDR91 WD repeat domain 91
WNT10B wingless-type MMTV integration site family, member 10B
ZNF223 zinc finger protein 223
ZNF430 zinc finger protein 430
ZNF443 zinc finger protein 443
ZNF671 zinc finger protein 671
ZNF721 zinc finger protein 721
ZSCAN9 zinc finger and SCAN domain containing 9