sulfaguanidine-4257 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the sulfaguanidine-4257 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A2M alpha-2-macroglobulin
AAK1 AP2 associated kinase 1
ABAT 4-aminobutyrate aminotransferase
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ADAM12 ADAM metallopeptidase domain 12
ADGRE3 adhesion G protein-coupled receptor E3
ADGRG1 adhesion G protein-coupled receptor G1
ADRB1 adrenoceptor beta 1
AGTR1 angiotensin II receptor, type 1
APOA1 apolipoprotein A-I
AQP6 aquaporin 6, kidney specific
ARL4D ADP-ribosylation factor-like 4D
ASCL1 achaete-scute family bHLH transcription factor 1
B3GALT2 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
BMPR1B bone morphogenetic protein receptor, type IB
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CAMK1G calcium/calmodulin-dependent protein kinase IG
CD6 CD6 molecule
CD96 CD96 molecule
CFB complement factor B
CLCNKB chloride channel, voltage-sensitive Kb
COL9A3 collagen, type IX, alpha 3
CSF1 colony stimulating factor 1 (macrophage)
CSHL1 chorionic somatomammotropin hormone-like 1
CSTA cystatin A (stefin A)
CYP2U1 cytochrome P450, family 2, subfamily U, polypeptide 1
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DUSP7 dual specificity phosphatase 7
EBF2 early B-cell factor 2
EDN3 endothelin 3
GDF10 growth differentiation factor 10
GNMT glycine N-methyltransferase
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GRIA3 glutamate receptor, ionotropic, AMPA 3
HAPLN2 hyaluronan and proteoglycan link protein 2
HFE hemochromatosis
IFIH1 interferon induced with helicase C domain 1
IGH immunoglobulin heavy locus
IHH indian hedgehog
INS insulin
KAZN kazrin, periplakin interacting protein
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1
KCNQ4 potassium channel, voltage gated KQT-like subfamily Q, member 4
KIF25 kinesin family member 25
KIR2DS4 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4
KLKB1 kallikrein B, plasma (Fletcher factor) 1
KRT12 keratin 12, type I
KRT14 keratin 14, type I
LARGE like-glycosyltransferase
LINC00302 long intergenic non-protein coding RNA 302
LMOD1 leiomodin 1 (smooth muscle)
LZTS1 leucine zipper, putative tumor suppressor 1
MBNL1 muscleblind-like splicing regulator 1
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
MINK1 misshapen-like kinase 1
MOBP myelin-associated oligodendrocyte basic protein
MORC1 MORC family CW-type zinc finger 1
MTMR3 myotubularin related protein 3
MYCNOS MYCN opposite strand
MYH6 myosin, heavy chain 6, cardiac muscle, alpha
NF1 neurofibromin 1
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NIPAL3 NIPA-like domain containing 3
NME8 NME/NM23 family member 8
NNAT neuronatin
NPR1 natriuretic peptide receptor 1
PCDHB17P protocadherin beta 17 pseudogene
PLVAP plasmalemma vesicle associated protein
PNPLA2 patatin-like phospholipase domain containing 2
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PRDM9 PR domain containing 9
PTPN21 protein tyrosine phosphatase, non-receptor type 21
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
RASAL2 RAS protein activator like 2
RFXAP regulatory factor X-associated protein
RIC3 RIC3 acetylcholine receptor chaperone
RPS6 ribosomal protein S6
S100A1 S100 calcium binding protein A1
SCGB2A1 secretoglobin, family 2A, member 1
SFRP5 secreted frizzled-related protein 5
SIGLEC8 sialic acid binding Ig-like lectin 8
SNED1 sushi, nidogen and EGF-like domains 1
T T, brachyury homolog (mouse)
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TAS2R3 taste receptor, type 2, member 3
TMPRSS2 transmembrane protease, serine 2
TRIM31 tripartite motif containing 31
TSSK2 testis-specific serine kinase 2
TTLL1 tubulin tyrosine ligase-like family member 1
TTYH1 tweety family member 1
UTF1 undifferentiated embryonic cell transcription factor 1
VWF von Willebrand factor
WISP2 WNT1 inducible signaling pathway protein 2
ZNF407 zinc finger protein 407
ZSCAN12 zinc finger and SCAN domain containing 12

decreased expression

Symbol Name
AMDHD2 amidohydrolase domain containing 2
AP1AR adaptor-related protein complex 1 associated regulatory protein
ARHGAP10 Rho GTPase activating protein 10
ARL15 ADP-ribosylation factor-like 15
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BGLAP bone gamma-carboxyglutamate (gla) protein
BOLA1 bolA family member 1
C11ORF71 chromosome 11 open reading frame 71
C1ORF159 chromosome 1 open reading frame 159
C22ORF29 chromosome 22 open reading frame 29
C4ORF29 chromosome 4 open reading frame 29
C9ORF91 chromosome 9 open reading frame 91
CAND2 cullin-associated and neddylation-dissociated 2 (putative)
CEP112 centrosomal protein 112kDa
CFAP69 cilia and flagella associated protein 69
CLDN11 claudin 11
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CRYBB2P1 crystallin, beta B2 pseudogene 1
CRYL1 crystallin, lambda 1
CTSO cathepsin O
CUZD1 CUB and zona pellucida-like domains 1
DCAF13 DDB1 and CUL4 associated factor 13
DPY19L2P2 DPY19L2 pseudogene 2
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1
E2F8 E2F transcription factor 8
EHF ets homologous factor
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
ERAP2 endoplasmic reticulum aminopeptidase 2
ETAA1 Ewing tumor-associated antigen 1
ETNK2 ethanolamine kinase 2
FAM69A family with sequence similarity 69, member A
FAT4 FAT atypical cadherin 4
FBXO2 F-box protein 2
FGF13 fibroblast growth factor 13
GID4 GID complex subunit 4
GLDC glycine dehydrogenase (decarboxylating)
GMEB1 glucocorticoid modulatory element binding protein 1
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
HDAC9 histone deacetylase 9
HIST1H4C histone cluster 1, H4c
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFNA17 interferon, alpha 17
IFT54 intraflagellar transport 54
IGSF3 immunoglobulin superfamily, member 3
IL11RA interleukin 11 receptor, alpha
INCENP inner centromere protein antigens 135/155kDa
INF2 inverted formin, FH2 and WH2 domain containing
JUNB jun B proto-oncogene
KATNBL1 katanin p80 subunit B-like 1
KIAA1107 KIAA1107
KIAA1462 KIAA1462
KLF7 Kruppel-like factor 7 (ubiquitous)
KLHL3 kelch-like family member 3
KPTN kaptin (actin binding protein)
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LIG4 ligase IV, DNA, ATP-dependent
LPPR4 lipid phosphate phosphatase-related protein type 4
MAN2C1 mannosidase, alpha, class 2C, member 1
MBTPS2 membrane-bound transcription factor peptidase, site 2
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
NDP Norrie disease (pseudoglioma)
NOD1 nucleotide-binding oligomerization domain containing 1
NR1H3 nuclear receptor subfamily 1, group H, member 3
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PALMD palmdelphin
PARD6A par-6 family cell polarity regulator alpha
PARP3 poly (ADP-ribose) polymerase family, member 3
PDE8B phosphodiesterase 8B
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
RNF126P1 ring finger protein 126 pseudogene 1
RP2 retinitis pigmentosa 2 (X-linked recessive)
RPL23AP32 ribosomal protein L23a pseudogene 32
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SCG5 secretogranin V
SECISBP2 SECIS binding protein 2
SERINC5 serine incorporator 5
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SPEG SPEG complex locus
STAG3L4 stromal antigen 3-like 4 (pseudogene)
TESK1 testis-specific kinase 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TLR2 toll-like receptor 2
TMEM242 transmembrane protein 242
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TXLNG taxilin gamma
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
ZNF227 zinc finger protein 227
ZNF254 zinc finger protein 254
ZNF33B zinc finger protein 33B
ZNF34 zinc finger protein 34
ZNF606 zinc finger protein 606