sulfamerazine-3616 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the sulfamerazine-3616 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM23 ADAM metallopeptidase domain 23
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7
ADGRE3 adhesion G protein-coupled receptor E3
ALPK1 alpha-kinase 1
ALPL alkaline phosphatase, liver/bone/kidney
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BCL3 B-cell CLL/lymphoma 3
BET1L Bet1 golgi vesicular membrane trafficking protein-like
BIN1 bridging integrator 1
BZRAP1 benzodiazepine receptor (peripheral) associated protein 1
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CARTPT CART prepropeptide
CASQ2 calsequestrin 2 (cardiac muscle)
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDK19 cyclin-dependent kinase 19
CDK3 cyclin-dependent kinase 3
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CLCF1 cardiotrophin-like cytokine factor 1
CLTC clathrin, heavy chain (Hc)
CNR1 cannabinoid receptor 1 (brain)
COLEC12 collectin sub-family member 12
CTBP2 C-terminal binding protein 2
CTSZ cathepsin Z
ECE1 endothelin converting enzyme 1
EDA ectodysplasin A
EMILIN2 elastin microfibril interfacer 2
EPHA3 EPH receptor A3
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
FHIT fragile histidine triad
FXYD7 FXYD domain containing ion transport regulator 7
FYB FYN binding protein
GJA4 gap junction protein, alpha 4, 37kDa
GLRA3 glycine receptor, alpha 3
GPR15 G protein-coupled receptor 15
GREB1 growth regulation by estrogen in breast cancer 1
GRM7 glutamate receptor, metabotropic 7
HBS1L HBS1-like translational GTPase
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2
HPX hemopexin
IGHA1 immunoglobulin heavy constant alpha 1
IL2RA interleukin 2 receptor, alpha
KCNK10 potassium channel, two pore domain subfamily K, member 10
KIAA1456 KIAA1456
KIF25 kinesin family member 25
KLRD1 killer cell lectin-like receptor subfamily D, member 1
KRT17 keratin 17, type I
KRT2 keratin 2, type II
KRT32 keratin 32, type I
KRT8 keratin 8, type II
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LAT2 linker for activation of T cells family, member 2
LTC4S leukotriene C4 synthase
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAN1A2 mannosidase, alpha, class 1A, member 2
MAPK4 mitogen-activated protein kinase 4
METTL7A methyltransferase like 7A
MPL MPL proto-oncogene, thrombopoietin receptor
MUC13 mucin 13, cell surface associated
NCR3 natural cytotoxicity triggering receptor 3
NF1 neurofibromin 1
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NOP14-AS1 NOP14 antisense RNA 1
NR4A1 nuclear receptor subfamily 4, group A, member 1
NRTN neurturin
OR7E24 olfactory receptor, family 7, subfamily E, member 24
PCDH1 protocadherin 1
PEAK1 pseudopodium-enriched atypical kinase 1
PKLR pyruvate kinase, liver and RBC
PKNOX2 PBX/knotted 1 homeobox 2
PKP2 plakophilin 2
PLCD1 phospholipase C, delta 1
PNPLA3 patatin-like phospholipase domain containing 3
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PTCH1 patched 1
PVT1 Pvt1 oncogene (non-protein coding)
RABGAP1L RAB GTPase activating protein 1-like
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RIN3 Ras and Rab interactor 3
RND1 Rho family GTPase 1
RPL13P5 ribosomal protein L13 pseudogene 5
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SIGLEC7 sialic acid binding Ig-like lectin 7
SIRT5 sirtuin 5
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SRPK2 SRSF protein kinase 2
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TRAPPC9 trafficking protein particle complex 9
TRBC1 T cell receptor beta constant 1
TRPM1 transient receptor potential cation channel, subfamily M, member 1
TTPA tocopherol (alpha) transfer protein
WNT16 wingless-type MMTV integration site family, member 16
ZFAND6 zinc finger, AN1-type domain 6
ZMAT4 zinc finger, matrin-type 4
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
ACBD4 acyl-CoA binding domain containing 4
ACSF2 acyl-CoA synthetase family member 2
AHSP alpha hemoglobin stabilizing protein
AMT aminomethyltransferase
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ARR3 arrestin 3, retinal (X-arrestin)
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BAG4 BCL2-associated athanogene 4
BCO1 beta-carotene oxygenase 1
BFSP1 beaded filament structural protein 1, filensin
BMP10 bone morphogenetic protein 10
BMP15 bone morphogenetic protein 15
C11ORF21 chromosome 11 open reading frame 21
C17ORF53 chromosome 17 open reading frame 53
C5ORF45 chromosome 5 open reading frame 45
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CAPG capping protein (actin filament), gelsolin-like
CAPN15 calpain 15
CD83 CD83 molecule
CENPO centromere protein O
CGA glycoprotein hormones, alpha polypeptide
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CORT cortistatin
CRIP1 cysteine-rich protein 1 (intestinal)
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DENND1A DENN/MADD domain containing 1A
DGKE diacylglycerol kinase, epsilon 64kDa
DNM3 dynamin 3
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
ETV7 ets variant 7
EXO5 exonuclease 5
FAM204A family with sequence similarity 204, member A
FFAR2 free fatty acid receptor 2
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GNG13 guanine nucleotide binding protein (G protein), gamma 13
HCAR3 hydroxycarboxylic acid receptor 3
HIST1H1D histone cluster 1, H1d
HIST1H2AI histone cluster 1, H2ai
HIST1H2AJ histone cluster 1, H2aj
HOXB2 homeobox B2
HOXC8 homeobox C8
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IL12RB1 interleukin 12 receptor, beta 1
INO80D INO80 complex subunit D
ITPKB inositol-trisphosphate 3-kinase B
LARP6 La ribonucleoprotein domain family, member 6
LIF leukemia inhibitory factor
LMAN1 lectin, mannose-binding, 1
LMNB1 lamin B1
LPXN leupaxin
LRRC37A2 leucine rich repeat containing 37, member A2
LYRM9 LYR motif containing 9
MAGEA5 melanoma antigen family A5
MAL mal, T-cell differentiation protein
MTCP1 mature T-cell proliferation 1
MYOZ3 myozenin 3
NDE1 nudE neurodevelopment protein 1
NOTCH1 notch 1
NPIPB15 nuclear pore complex interacting protein family, member B15
NPY4R neuropeptide Y receptor Y4
NT5DC3 5'-nucleotidase domain containing 3
OR1D2 olfactory receptor, family 1, subfamily D, member 2
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PGBD5 piggyBac transposable element derived 5
PLSCR4 phospholipid scramblase 4
PRKCE protein kinase C, epsilon
PRPH peripherin
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
QPCTL glutaminyl-peptide cyclotransferase-like
RAB40AL RAB40A, member RAS oncogene family-like
RECQL4 RecQ protein-like 4
REM1 RAS (RAD and GEM)-like GTP-binding 1
RNF123 ring finger protein 123
RNF39 ring finger protein 39
SCRN3 secernin 3
SDC3 syndecan 3
SGCE sarcoglycan, epsilon
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
STAB2 stabilin 2
STX1A syntaxin 1A (brain)
THNSL2 threonine synthase-like 2 (S. cerevisiae)
TK1 thymidine kinase 1, soluble
TUBA3C tubulin, alpha 3c
USP20 ubiquitin specific peptidase 20
VIPR1 vasoactive intestinal peptide receptor 1
ZIC3 Zic family member 3
ZNF329 zinc finger protein 329
ZNF442 zinc finger protein 442
ZSCAN2 zinc finger and SCAN domain containing 2