sulfamerazine-4740 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the sulfamerazine-4740 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAK1 AP2 associated kinase 1
AAMDC adipogenesis associated, Mth938 domain containing
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ACVR1B activin A receptor, type IB
ADORA1 adenosine A1 receptor
AMACR alpha-methylacyl-CoA racemase
AMPD3 adenosine monophosphate deaminase 3
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
BAIAP3 BAI1-associated protein 3
BMP15 bone morphogenetic protein 15
CALD1 caldesmon 1
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCDC40 coiled-coil domain containing 40
CD6 CD6 molecule
CDHR2 cadherin-related family member 2
CEP135 centrosomal protein 135kDa
CLIC2 chloride intracellular channel 2
CYLD cylindromatosis (turban tumor syndrome)
DNALI1 dynein, axonemal, light intermediate chain 1
DOK2 docking protein 2, 56kDa
EHD2 EH-domain containing 2
EPN1 epsin 1
EPYC epiphycan
EVA1B eva-1 homolog B (C. elegans)
FBXL7 F-box and leucine-rich repeat protein 7
FRMD1 FERM domain containing 1
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GAS7 growth arrest-specific 7
GFAP glial fibrillary acidic protein
GFI1 growth factor independent 1 transcription repressor
GIF gastric intrinsic factor (vitamin B synthesis)
GIPR gastric inhibitory polypeptide receptor
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GRIA3 glutamate receptor, ionotropic, AMPA 3
GRK5 G protein-coupled receptor kinase 5
GSK3A glycogen synthase kinase 3 alpha
HIC2 hypermethylated in cancer 2
HMGN5 high mobility group nucleosome binding domain 5
HOXB9 homeobox B9
IAPP islet amyloid polypeptide
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IFNA14 interferon, alpha 14
IGHM immunoglobulin heavy constant mu
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
JRK Jrk homolog (mouse)
KHK ketohexokinase (fructokinase)
KIAA1456 KIAA1456
KIAA1654 KIAA1654 protein
KIF1C kinesin family member 1C
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KRTAP9-9 keratin associated protein 9-9
LAMB4 laminin, beta 4
LENEP lens epithelial protein
LINC00260 long intergenic non-protein coding RNA 260
MAL mal, T-cell differentiation protein
MED25 mediator complex subunit 25
MSR1 macrophage scavenger receptor 1
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTSS1L metastasis suppressor 1-like
NABP1 nucleic acid binding protein 1
NOP14-AS1 NOP14 antisense RNA 1
PIGC phosphatidylinositol glycan anchor biosynthesis, class C
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PPP1R37 protein phosphatase 1, regulatory subunit 37
PSCA prostate stem cell antigen
PTPRM protein tyrosine phosphatase, receptor type, M
RAB3B RAB3B, member RAS oncogene family
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RERE arginine-glutamic acid dipeptide (RE) repeats
RFPL1 ret finger protein-like 1
RGS10 regulator of G-protein signaling 10
RGS20 regulator of G-protein signaling 20
SCAPER S-phase cyclin A-associated protein in the ER
SCN10A sodium channel, voltage gated, type X alpha subunit
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SERHL2 serine hydrolase-like 2
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC13A3 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
SLC14A2 solute carrier family 14 (urea transporter), member 2
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLCO3A1 solute carrier organic anion transporter family, member 3A1
SNED1 sushi, nidogen and EGF-like domains 1
SORBS2 sorbin and SH3 domain containing 2
SSX1 synovial sarcoma, X breakpoint 1
TBX5 T-box 5
TECPR2 tectonin beta-propeller repeat containing 2
THOC5 THO complex 5
TLX2 T-cell leukemia homeobox 2
TMPRSS4 transmembrane protease, serine 4
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TSPAN9 tetraspanin 9
ZNF362 zinc finger protein 362
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
ABHD14A abhydrolase domain containing 14A
ADAP2 ArfGAP with dual PH domains 2
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
AGMAT agmatine ureohydrolase (agmatinase)
ANKFY1 ankyrin repeat and FYVE domain containing 1
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
B9D2 B9 protein domain 2
BCAS1 breast carcinoma amplified sequence 1
BRAF B-Raf proto-oncogene, serine/threonine kinase
C17ORF80 chromosome 17 open reading frame 80
C2ORF54 chromosome 2 open reading frame 54
CAMK1 calcium/calmodulin-dependent protein kinase I
CAPRIN2 caprin family member 2
CCDC6 coiled-coil domain containing 6
CD8A CD8a molecule
CENPJ centromere protein J
CEP97 centrosomal protein 97kDa
CFAP44 cilia and flagella associated protein 44
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CIR1 corepressor interacting with RBPJ, 1
CRY2 cryptochrome circadian clock 2
CSF1R colony stimulating factor 1 receptor
CUZD1 CUB and zona pellucida-like domains 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DGKE diacylglycerol kinase, epsilon 64kDa
DPY19L1P1 DPY19L1 pseudogene 1
EFNA3 ephrin-A3
ELSPBP1 epididymal sperm binding protein 1
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ETNK2 ethanolamine kinase 2
FRK fyn-related Src family tyrosine kinase
GBP2 guanylate binding protein 2, interferon-inducible
GID4 GID complex subunit 4
GPATCH2L G patch domain containing 2-like
HIRA histone cell cycle regulator
HIST1H4D histone cluster 1, H4d
HMOX1 heme oxygenase 1
HOXC10 homeobox C10
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
IDI2-AS1 IDI2 antisense RNA 1
IFI6 interferon, alpha-inducible protein 6
INCENP inner centromere protein antigens 135/155kDa
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KIAA0319L KIAA0319-like
LGALS4 lectin, galactoside-binding, soluble, 4
LINC00339 long intergenic non-protein coding RNA 339
LY6G6C lymphocyte antigen 6 complex, locus G6C
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MTA2 metastasis associated 1 family, member 2
MTERF1 mitochondrial transcription termination factor 1
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NEUROD4 neuronal differentiation 4
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NKX3-2 NK3 homeobox 2
NR1H3 nuclear receptor subfamily 1, group H, member 3
OLFML2A olfactomedin-like 2A
PARP16 poly (ADP-ribose) polymerase family, member 16
PDIA3 protein disulfide isomerase family A, member 3
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PEX26 peroxisomal biogenesis factor 26
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLA2G3 phospholipase A2, group III
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRSS22 protease, serine, 22
R3HCC1L R3H domain and coiled-coil containing 1-like
RAI2 retinoic acid induced 2
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF208 ring finger protein 208
SAMD9 sterile alpha motif domain containing 9
SAYSD1 SAYSVFN motif domain containing 1
SDC3 syndecan 3
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SMR3A submaxillary gland androgen regulated protein 3A
SP1 Sp1 transcription factor
SPINK5 serine peptidase inhibitor, Kazal type 5
SRD5A3 steroid 5 alpha-reductase 3
STRN striatin, calmodulin binding protein
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
THBS3 thrombospondin 3
TMEM254 transmembrane protein 254
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
USP36 ubiquitin specific peptidase 36
WDR62 WD repeat domain 62
ZBTB33 zinc finger and BTB domain containing 33
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF16 zinc finger protein 16
ZNF204P zinc finger protein 204, pseudogene
ZNF286A zinc finger protein 286A
ZNF37BP zinc finger protein 37B, pseudogene
ZNF675 zinc finger protein 675
ZNF701 zinc finger protein 701
ZNF816 zinc finger protein 816