sulfamethizole-5798 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the sulfamethizole-5798 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAK1 AP2 associated kinase 1
ACAN aggrecan
ADAM12 ADAM metallopeptidase domain 12
ADAMDEC1 ADAM-like, decysin 1
ADRBK2 adrenergic, beta, receptor kinase 2
AFF1 AF4/FMR2 family, member 1
ARNT aryl hydrocarbon receptor nuclear translocator
ARTN artemin
ATXN8OS ATXN8 opposite strand (non-protein coding)
AURKC aurora kinase C
BCL2 B-cell CLL/lymphoma 2
BTG2 BTG family, member 2
C9ORF40 chromosome 9 open reading frame 40
CA9 carbonic anhydrase IX
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CD79B CD79b molecule, immunoglobulin-associated beta
CD80 CD80 molecule
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CEL carboxyl ester lipase
CEP152 centrosomal protein 152kDa
CHI3L2 chitinase 3-like 2
CHRDL1 chordin-like 1
CLIC3 chloride intracellular channel 3
CNR1 cannabinoid receptor 1 (brain)
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
CORO2B coronin, actin binding protein, 2B
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CPNE7 copine VII
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
CTRC chymotrypsin C (caldecrin)
CYP2A7 cytochrome P450, family 2, subfamily A, polypeptide 7
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11
DESI2 desumoylating isopeptidase 2
DFNB31 deafness, autosomal recessive 31
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DLK2 delta-like 2 homolog (Drosophila)
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DOC2B double C2-like domains, beta
EPX eosinophil peroxidase
ESRRA estrogen-related receptor alpha
FAM182B family with sequence similarity 182, member B
FCAR Fc fragment of IgA receptor
FGL2 fibrinogen-like 2
FMO5 flavin containing monooxygenase 5
GAS7 growth arrest-specific 7
GATA3 GATA binding protein 3
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GK3P glycerol kinase 3 pseudogene
GRIK5 glutamate receptor, ionotropic, kainate 5
GSK3A glycogen synthase kinase 3 alpha
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
IL12A interleukin 12A
INHBC inhibin, beta C
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCNK13 potassium channel, two pore domain subfamily K, member 13
KCTD14 potassium channel tetramerization domain containing 14
KIF1A kinesin family member 1A
KRT34 keratin 34, type I
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
LPL lipoprotein lipase
MORN1 MORN repeat containing 1
MUC8 mucin 8
MYH11 myosin, heavy chain 11, smooth muscle
NEB nebulin
NF1 neurofibromin 1
NME5 NME/NM23 family member 5
NOX1 NADPH oxidase 1
OCM2 oncomodulin 2
PDE4C phosphodiesterase 4C, cAMP-specific
PDLIM3 PDZ and LIM domain 3
PECAM1 platelet/endothelial cell adhesion molecule 1
PLIN2 perilipin 2
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PRDM14 PR domain containing 14
PRKCA protein kinase C, alpha
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
RAB6B RAB6B, member RAS oncogene family
RABEP2 rabaptin, RAB GTPase binding effector protein 2
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
REEP2 receptor accessory protein 2
RGS12 regulator of G-protein signaling 12
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SOCS3 suppressor of cytokine signaling 3
SOX30 SRY (sex determining region Y)-box 30
TAPBP TAP binding protein (tapasin)
THSD4 thrombospondin, type I, domain containing 4
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TXNRD3 thioredoxin reductase 3
WNT2B wingless-type MMTV integration site family, member 2B
WSB1 WD repeat and SOCS box containing 1
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
ZHX3 zinc fingers and homeoboxes 3
ZNF391 zinc finger protein 391
ZNF783 zinc finger family member 783

decreased expression

Symbol Name
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ART1 ADP-ribosyltransferase 1
ATAD5 ATPase family, AAA domain containing 5
ATAT1 alpha tubulin acetyltransferase 1
BAHD1 bromo adjacent homology domain containing 1
BCL9 B-cell CLL/lymphoma 9
BET1L Bet1 golgi vesicular membrane trafficking protein-like
BFSP1 beaded filament structural protein 1, filensin
BGLAP bone gamma-carboxyglutamate (gla) protein
C1QTNF1 C1q and tumor necrosis factor related protein 1
C1R complement component 1, r subcomponent
CCDC186 coiled-coil domain containing 186
CCDC71 coiled-coil domain containing 71
CCNJ cyclin J
CCNO cyclin O
CD82 CD82 molecule
CISH cytokine inducible SH2-containing protein
CLCA1 chloride channel accessory 1
CORO1A coronin, actin binding protein, 1A
CPEB1 cytoplasmic polyadenylation element binding protein 1
CREB5 cAMP responsive element binding protein 5
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
EGR2 early growth response 2
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FAM120C family with sequence similarity 120C
FGL1 fibrinogen-like 1
FRS2 fibroblast growth factor receptor substrate 2
GPATCH3 G patch domain containing 3
GPR19 G protein-coupled receptor 19
GRTP1 growth hormone regulated TBC protein 1
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HIRA histone cell cycle regulator
HIST1H4E histone cluster 1, H4e
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HMOX1 heme oxygenase 1
HOXA7 homeobox A7
HOXC10 homeobox C10
HOXC11 homeobox C11
HOXC13 homeobox C13
HOXC5 homeobox C5
HSF2BP heat shock transcription factor 2 binding protein
HSPA1L heat shock 70kDa protein 1-like
KIAA0754 KIAA0754
KIRREL kin of IRRE like (Drosophila)
LAX1 lymphocyte transmembrane adaptor 1
LMCD1 LIM and cysteine-rich domains 1
LOC729164 hCG1732469
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MMRN2 multimerin 2
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MVD mevalonate (diphospho) decarboxylase
MYO1D myosin ID
MYO1F myosin IF
NECAB3 N-terminal EF-hand calcium binding protein 3
NEK11 NIMA-related kinase 11
NT5DC3 5'-nucleotidase domain containing 3
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PDE8B phosphodiesterase 8B
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PHF14 PHD finger protein 14
POM121 POM121 transmembrane nucleoporin
POMT2 protein-O-mannosyltransferase 2
PTPRH protein tyrosine phosphatase, receptor type, H
RAB3A RAB3A, member RAS oncogene family
RGCC regulator of cell cycle
RIN1 Ras and Rab interactor 1
RNF2 ring finger protein 2
RUSC2 RUN and SH3 domain containing 2
SCG2 secretogranin II
SRD5A3 steroid 5 alpha-reductase 3
STXBP6 syntaxin binding protein 6 (amisyn)
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TGFB3 transforming growth factor, beta 3
TLR2 toll-like receptor 2
TMC7 transmembrane channel-like 7
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
USP20 ubiquitin specific peptidase 20
VASH1 vasohibin 1
WDR33 WD repeat domain 33
ZBTB6 zinc finger and BTB domain containing 6
ZFP30 ZFP30 zinc finger protein
ZNF177 zinc finger protein 177
ZNF230 zinc finger protein 230
ZNF358 zinc finger protein 358
ZNF41 zinc finger protein 41
ZNF702P zinc finger protein 702, pseudogene
ZNF74 zinc finger protein 74
ZNF76 zinc finger protein 76