sulfamethizole-6099 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

193 genes differentially expressed following the sulfamethizole-6099 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAA2 acetyl-CoA acyltransferase 2
ACAN aggrecan
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7
AIM1L absent in melanoma 1-like
ANXA2P1 annexin A2 pseudogene 1
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit
ATN1 atrophin 1
ATP11A ATPase, class VI, type 11A
BIN1 bridging integrator 1
BTF3P11 basic transcription factor 3 pseudogene 11
C7ORF69 chromosome 7 open reading frame 69
CD163 CD163 molecule
CD200 CD200 molecule
CD79B CD79b molecule, immunoglobulin-associated beta
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CLCN7 chloride channel, voltage-sensitive 7
CNTLN centlein, centrosomal protein
COL13A1 collagen, type XIII, alpha 1
COL4A1 collagen, type IV, alpha 1
COL6A1 collagen, type VI, alpha 1
CYBB cytochrome b-245, beta polypeptide
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DBT dihydrolipoamide branched chain transacylase E2
DCN decorin
DGCR8 DGCR8 microprocessor complex subunit
DVL3 dishevelled segment polarity protein 3
EFCAB11 EF-hand calcium binding domain 11
ENO3 enolase 3 (beta, muscle)
EPYC epiphycan
ETV7 ets variant 7
FGF4 fibroblast growth factor 4
FGFR2 fibroblast growth factor receptor 2
GAP43 growth associated protein 43
GJA4 gap junction protein, alpha 4, 37kDa
GLP1R glucagon-like peptide 1 receptor
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GNAT1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1
GPM6A glycoprotein M6A
GRK4 G protein-coupled receptor kinase 4
GRM1 glutamate receptor, metabotropic 1
HAPLN1 hyaluronan and proteoglycan link protein 1
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HR hair growth associated
HRH3 histamine receptor H3
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
IKZF3 IKAROS family zinc finger 3 (Aiolos)
IL11 interleukin 11
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KHSRP KH-type splicing regulatory protein
KIAA0040 KIAA0040
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLK1 kallikrein 1
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
LY9 lymphocyte antigen 9
MRPS18C mitochondrial ribosomal protein S18C
MUC6 mucin 6, oligomeric mucus/gel-forming
NAG18 NAG18 mRNA
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
NR2E3 nuclear receptor subfamily 2, group E, member 3
PHLDB1 pleckstrin homology-like domain, family B, member 1
PLEK pleckstrin
PLSCR2 phospholipid scramblase 2
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PPP5C protein phosphatase 5, catalytic subunit
PRTN3 proteinase 3
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RGS14 regulator of G-protein signaling 14
RGS5 regulator of G-protein signaling 5
ROR2 receptor tyrosine kinase-like orphan receptor 2
RORC RAR-related orphan receptor C
S100A8 S100 calcium binding protein A8
SCAND2P SCAN domain containing 2 pseudogene
SCN11A sodium channel, voltage gated, type XI alpha subunit
SKAP1 src kinase associated phosphoprotein 1
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SNTA1 syntrophin, alpha 1
SORBS3 sorbin and SH3 domain containing 3
SPTAN1 spectrin, alpha, non-erythrocytic 1
SSX3 synovial sarcoma, X breakpoint 3
STARD8 StAR-related lipid transfer (START) domain containing 8
TBC1D19 TBC1 domain family, member 19
TBX3 T-box 3
TENM1 teneurin transmembrane protein 1
TM4SF4 transmembrane 4 L six family member 4
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRAF3IP3 TRAF3 interacting protein 3
TRIM2 tripartite motif containing 2
TTLL3 tubulin tyrosine ligase-like family member 3
VCAN versican
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VIPR1 vasoactive intestinal peptide receptor 1
ZFP64 ZFP64 zinc finger protein
ZNF155 zinc finger protein 155

decreased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
AFAP1 actin filament associated protein 1
ARRB1 arrestin, beta 1
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BATF basic leucine zipper transcription factor, ATF-like
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C2ORF27A chromosome 2 open reading frame 27A
CAMKMT calmodulin-lysine N-methyltransferase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCDC9 coiled-coil domain containing 9
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CEP164 centrosomal protein 164kDa
CES3 carboxylesterase 3
CFAP45 cilia and flagella associated protein 45
CRYBG3 beta-gamma crystallin domain containing 3
CSF1R colony stimulating factor 1 receptor
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EFNA3 ephrin-A3
ELOVL4 ELOVL fatty acid elongase 4
EPB41L5 erythrocyte membrane protein band 4.1 like 5
FAM189A2 family with sequence similarity 189, member A2
FGD1 FYVE, RhoGEF and PH domain containing 1
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GLI3 GLI family zinc finger 3
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GRB7 growth factor receptor-bound protein 7
HDAC5 histone deacetylase 5
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIST1H2AL histone cluster 1, H2al
HIST1H3B histone cluster 1, H3b
HIST1H4D histone cluster 1, H4d
HOXB2 homeobox B2
HOXC5 homeobox C5
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
IFI35 interferon-induced protein 35
IFNA14 interferon, alpha 14
IL22 interleukin 22
ITGA10 integrin, alpha 10
KIF13A kinesin family member 13A
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
LENEP lens epithelial protein
LIN7A lin-7 homolog A (C. elegans)
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAP9 microtubule-associated protein 9
MIS18BP1 MIS18 binding protein 1
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MVD mevalonate (diphospho) decarboxylase
MYOZ3 myozenin 3
NME5 NME/NM23 family member 5
NOL10 nucleolar protein 10
NTF3 neurotrophin 3
OLFML2A olfactomedin-like 2A
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PCDH12 protocadherin 12
PCNXL4 pecanex-like 4 (Drosophila)
PDE12 phosphodiesterase 12
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PEX26 peroxisomal biogenesis factor 26
PHC1 polyhomeotic homolog 1 (Drosophila)
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PLEKHO1 pleckstrin homology domain containing, family O member 1
POLL polymerase (DNA directed), lambda
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
RAB40C RAB40C, member RAS oncogene family
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RFXAP regulatory factor X-associated protein
RNF126P1 ring finger protein 126 pseudogene 1
RPAP1 RNA polymerase II associated protein 1
RPL10L ribosomal protein L10-like
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SLMO1 slowmo homolog 1 (Drosophila)
SND1-IT1 SND1 intronic transcript 1
SPINK4 serine peptidase inhibitor, Kazal type 4
SRD5A3 steroid 5 alpha-reductase 3
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TFF2 trefoil factor 2
TGFBR1 transforming growth factor, beta receptor 1
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TMEM158 transmembrane protein 158 (gene/pseudogene)
TNRC6B trinucleotide repeat containing 6B
UBTD1 ubiquitin domain containing 1
USB1 U6 snRNA biogenesis 1
WLS wntless Wnt ligand secretion mediator
XDH xanthine dehydrogenase
ZNF551 zinc finger protein 551
ZNF586 zinc finger protein 586
ZNF701 zinc finger protein 701
ZNF816 zinc finger protein 816