| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the sulfamethoxazole-3667 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACO2 | aconitase 2, mitochondrial |
| ACSM1 | acyl-CoA synthetase medium-chain family member 1 |
| ACTN3 | actinin, alpha 3 (gene/pseudogene) |
| ADAM22 | ADAM metallopeptidase domain 22 |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 |
| AGFG1 | ArfGAP with FG repeats 1 |
| ANXA10 | annexin A10 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit |
| APP | amyloid beta (A4) precursor protein |
| ARMC4 | armadillo repeat containing 4 |
| ARSA | arylsulfatase A |
| ASCL1 | achaete-scute family bHLH transcription factor 1 |
| BBC3 | BCL2 binding component 3 |
| BCL2L10 | BCL2-like 10 (apoptosis facilitator) |
| BET1L | Bet1 golgi vesicular membrane trafficking protein-like |
| BMP10 | bone morphogenetic protein 10 |
| CACNG5 | calcium channel, voltage-dependent, gamma subunit 5 |
| CALML3 | calmodulin-like 3 |
| CCDC144A | coiled-coil domain containing 144A |
| CD200 | CD200 molecule |
| CD58 | CD58 molecule |
| CDC14A | cell division cycle 14A |
| CDRT1 | CMT1A duplicated region transcript 1 |
| CFAP70 | cilia and flagella associated protein 70 |
| CHAT | choline O-acetyltransferase |
| CLDN17 | claudin 17 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| COL2A1 | collagen, type II, alpha 1 |
| CPB2 | carboxypeptidase B2 (plasma) |
| DDX28 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 |
| DKFZP434L187 | uncharacterized LOC26082 |
| DNPH1 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 |
| EFEMP2 | EGF containing fibulin-like extracellular matrix protein 2 |
| EGR1 | early growth response 1 |
| F13A1 | coagulation factor XIII, A1 polypeptide |
| FAM174B | family with sequence similarity 174, member B |
| FILIP1L | filamin A interacting protein 1-like |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FNDC4 | fibronectin type III domain containing 4 |
| GUCY2D | guanylate cyclase 2D, membrane (retina-specific) |
| HAMP | hepcidin antimicrobial peptide |
| HIST1H3F | histone cluster 1, H3f |
| HTR4 | 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IFFO1 | intermediate filament family orphan 1 |
| IGFBP7 | insulin-like growth factor binding protein 7 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 |
| KIF25 | kinesin family member 25 |
| KLK13 | kallikrein-related peptidase 13 |
| KSR1 | kinase suppressor of ras 1 |
| LECT1 | leukocyte cell derived chemotaxin 1 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 |
| LILRP2 | leukocyte immunoglobulin-like receptor pseudogene 2 |
| LIMK1 | LIM domain kinase 1 |
| LOC284244 | uncharacterized LOC284244 |
| LRRN2 | leucine rich repeat neuronal 2 |
| MBD2 | methyl-CpG binding domain protein 2 |
| MEGF6 | multiple EGF-like-domains 6 |
| MUC3B | mucin 3B, cell surface associated |
| NCR2 | natural cytotoxicity triggering receptor 2 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NLGN1 | neuroligin 1 |
| NOD2 | nucleotide-binding oligomerization domain containing 2 |
| NPFF | neuropeptide FF-amide peptide precursor |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NRN1 | neuritin 1 |
| OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF |
| OR2C1 | olfactory receptor, family 2, subfamily C, member 1 |
| PAX3 | paired box 3 |
| PBX1 | pre-B-cell leukemia homeobox 1 |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PCDHB13 | protocadherin beta 13 |
| PCDHB3 | protocadherin beta 3 |
| PIGR | polymeric immunoglobulin receptor |
| PIK3R5 | phosphoinositide-3-kinase, regulatory subunit 5 |
| PLA2G5 | phospholipase A2, group V |
| PLEK | pleckstrin |
| PLP1 | proteolipid protein 1 |
| PNMAL1 | paraneoplastic Ma antigen family-like 1 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PTAFR | platelet-activating factor receptor |
| PYY | peptide YY |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RAVER2 | ribonucleoprotein, PTB-binding 2 |
| RBM48 | RNA binding motif protein 48 |
| SIGLEC8 | sialic acid binding Ig-like lectin 8 |
| SLAMF7 | SLAM family member 7 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TAT | tyrosine aminotransferase |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TSC22D2 | TSC22 domain family, member 2 |
| TSPAN9 | tetraspanin 9 |
| TTC38 | tetratricopeptide repeat domain 38 |
| WTAP | Wilms tumor 1 associated protein |
| ZMAT4 | zinc finger, matrin-type 4 |
| Symbol | Name |
|---|---|
| ADAT1 | adenosine deaminase, tRNA-specific 1 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| AGMAT | agmatine ureohydrolase (agmatinase) |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ALPK1 | alpha-kinase 1 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| BDKRB1 | bradykinin receptor B1 |
| C17ORF53 | chromosome 17 open reading frame 53 |
| C17ORF80 | chromosome 17 open reading frame 80 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| CCDC85C | coiled-coil domain containing 85C |
| CHRNA5 | cholinergic receptor, nicotinic, alpha 5 (neuronal) |
| COBL | cordon-bleu WH2 repeat protein |
| COL4A3BP | collagen, type IV, alpha 3 (Goodpasture antigen) binding protein |
| CRY2 | cryptochrome circadian clock 2 |
| CTAGE9 | CTAGE family, member 9 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| CYP20A1 | cytochrome P450, family 20, subfamily A, polypeptide 1 |
| CYP2R1 | cytochrome P450, family 2, subfamily R, polypeptide 1 |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| DENND5B | DENN/MADD domain containing 5B |
| DEPTOR | DEP domain containing MTOR-interacting protein |
| DNAJC22 | DnaJ (Hsp40) homolog, subfamily C, member 22 |
| EFNA3 | ephrin-A3 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| EXOC5 | exocyst complex component 5 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FLCN | folliculin |
| FNTB | farnesyltransferase, CAAX box, beta |
| FZD8 | frizzled class receptor 8 |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GLB1L | galactosidase, beta 1-like |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GPR176 | G protein-coupled receptor 176 |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IL6 | interleukin 6 |
| IL7 | interleukin 7 |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| IREB2 | iron-responsive element binding protein 2 |
| KLHL36 | kelch-like family member 36 |
| KRT4 | keratin 4, type II |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LINC00260 | long intergenic non-protein coding RNA 260 |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| MAGEF1 | melanoma antigen family F1 |
| METTL16 | methyltransferase like 16 |
| MPI | mannose phosphate isomerase |
| NEK11 | NIMA-related kinase 11 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NR3C2 | nuclear receptor subfamily 3, group C, member 2 |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PARD6A | par-6 family cell polarity regulator alpha |
| PARP3 | poly (ADP-ribose) polymerase family, member 3 |
| PCOLCE | procollagen C-endopeptidase enhancer |
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) |
| PLEKHG6 | pleckstrin homology domain containing, family G (with RhoGef domain) member 6 |
| POLR2J2 | polymerase (RNA) II (DNA directed) polypeptide J2 |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PTK6 | protein tyrosine kinase 6 |
| RARS | arginyl-tRNA synthetase |
| RNF122 | ring finger protein 122 |
| RPRM | reprimo, TP53 dependent G2 arrest mediator candidate |
| SCAI | suppressor of cancer cell invasion |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SMO | smoothened, frizzled class receptor |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| SYTL2 | synaptotagmin-like 2 |
| TEX40 | testis expressed 40 |
| TFCP2L1 | transcription factor CP2-like 1 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMEM230 | transmembrane protein 230 |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| TRMT2B | tRNA methyltransferase 2 homolog B (S. cerevisiae) |
| TSPYL5 | TSPY-like 5 |
| UGT8 | UDP glycosyltransferase 8 |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| WDR76 | WD repeat domain 76 |
| WFDC2 | WAP four-disulfide core domain 2 |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZNF197 | zinc finger protein 197 |
| ZNF264 | zinc finger protein 264 |
| ZNF426 | zinc finger protein 426 |
| ZNF510 | zinc finger protein 510 |
| ZNF652 | zinc finger protein 652 |
| ZNF667 | zinc finger protein 667 |
| ZNF721 | zinc finger protein 721 |
| ZNF749 | zinc finger protein 749 |
| ZNF91 | zinc finger protein 91 |
| ZW10 | zw10 kinetochore protein |
