sulfametoxydiazine-2712 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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195 genes differentially expressed following the sulfametoxydiazine-2712 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ADAM20 ADAM metallopeptidase domain 20
ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif, 20
ADRBK1 adrenergic, beta, receptor kinase 1
AIRE autoimmune regulator
ALDOAP2 aldolase A, fructose-bisphosphate pseudogene 2
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
AP1M2 adaptor-related protein complex 1, mu 2 subunit
ASB4 ankyrin repeat and SOCS box containing 4
ATP10A ATPase, class V, type 10A
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3
BAZ2B bromodomain adjacent to zinc finger domain, 2B
BCL3 B-cell CLL/lymphoma 3
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C11ORF63 chromosome 11 open reading frame 63
CA5B carbonic anhydrase VB, mitochondrial
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD24 CD24 molecule
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CDO1 cysteine dioxygenase type 1
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
COL8A2 collagen, type VIII, alpha 2
CREB5 cAMP responsive element binding protein 5
CRHR2 corticotropin releasing hormone receptor 2
CST4 cystatin S
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DCN decorin
DGCR2 DiGeorge syndrome critical region gene 2
DLX2 distal-less homeobox 2
DMP1 dentin matrix acidic phosphoprotein 1
DNAI2 dynein, axonemal, intermediate chain 2
DPP4 dipeptidyl-peptidase 4
DPY19L1P1 DPY19L1 pseudogene 1
EPYC epiphycan
EXTL3 exostosin-like glycosyltransferase 3
EYA2 EYA transcriptional coactivator and phosphatase 2
FAM65B family with sequence similarity 65, member B
FGF6 fibroblast growth factor 6
FZD4 frizzled class receptor 4
GABARAPL3 GABA(A) receptors associated protein like 3, pseudogene
GAS1 growth arrest-specific 1
GJA8 gap junction protein, alpha 8, 50kDa
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GPM6B glycoprotein M6B
GPR153 G protein-coupled receptor 153
HIST1H2AJ histone cluster 1, H2aj
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
IGFBP6 insulin-like growth factor binding protein 6
IGL immunoglobulin lambda locus
IKZF4 IKAROS family zinc finger 4 (Eos)
IL36G interleukin 36, gamma
ITGB1BP2 integrin beta 1 binding protein (melusin) 2
JPH3 junctophilin 3
KIF1A kinesin family member 1A
KRT6B keratin 6B, type II
LECT1 leukocyte cell derived chemotaxin 1
LILRP2 leukocyte immunoglobulin-like receptor pseudogene 2
LMNA lamin A/C
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MTMR8 myotubularin related protein 8
MTSS1 metastasis suppressor 1
NCOR2 nuclear receptor corepressor 2
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NOTCH3 notch 3
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
PAX4 paired box 4
PCDHGA9 protocadherin gamma subfamily A, 9
PDCD6 programmed cell death 6
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PKNOX2 PBX/knotted 1 homeobox 2
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLEKHS1 pleckstrin homology domain containing, family S member 1
PRB1 proline-rich protein BstNI subfamily 1
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTGER3 prostaglandin E receptor 3 (subtype EP3)
RAB11B RAB11B, member RAS oncogene family
RAB26 RAB26, member RAS oncogene family
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RPL23AP32 ribosomal protein L23a pseudogene 32
RRAD Ras-related associated with diabetes
SAA4 serum amyloid A4, constitutive
SAMD14 sterile alpha motif domain containing 14
SCIN scinderin
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SIPA1L3 signal-induced proliferation-associated 1 like 3
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SMAD6 SMAD family member 6
SMCP sperm mitochondria-associated cysteine-rich protein
SPRR2B small proline-rich protein 2B
TACR1 tachykinin receptor 1
TDRD12 tudor domain containing 12
TFDP3 transcription factor Dp family, member 3
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
VPS9D1 VPS9 domain containing 1
WDR1 WD repeat domain 1
ZER1 zyg-11 related, cell cycle regulator
ZNF518A zinc finger protein 518A

decreased expression

Symbol Name
ACP6 acid phosphatase 6, lysophosphatidic
AMDHD2 amidohydrolase domain containing 2
ANXA6 annexin A6
ARMC6 armadillo repeat containing 6
ARRB1 arrestin, beta 1
BPHL biphenyl hydrolase-like (serine hydrolase)
BSPRY B-box and SPRY domain containing
C17ORF53 chromosome 17 open reading frame 53
C1ORF159 chromosome 1 open reading frame 159
C9ORF3 chromosome 9 open reading frame 3
CCDC132 coiled-coil domain containing 132
CCDC57 coiled-coil domain containing 57
CCDC69 coiled-coil domain containing 69
CCDC85C coiled-coil domain containing 85C
CD300C CD300c molecule
CDC42SE1 CDC42 small effector 1
CDK6 cyclin-dependent kinase 6
CHMP1A charged multivesicular body protein 1A
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CLTCL1 clathrin, heavy chain-like 1
COG4 component of oligomeric golgi complex 4
DHRS7B dehydrogenase/reductase (SDR family) member 7B
DNM3 dynamin 3
DOC2A double C2-like domains, alpha
DOCK4 dedicator of cytokinesis 4
DZANK1 double zinc ribbon and ankyrin repeat domains 1
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
FAM188A family with sequence similarity 188, member A
FAM50B family with sequence similarity 50, member B
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FEM1C fem-1 homolog c (C. elegans)
FLCN folliculin
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPC3 glypican 3
GPR22 G protein-coupled receptor 22
GPR27 G protein-coupled receptor 27
GPR65 G protein-coupled receptor 65
HCAR3 hydroxycarboxylic acid receptor 3
HIST1H1E histone cluster 1, H1e
HLA-DMA major histocompatibility complex, class II, DM alpha
IK IK cytokine, down-regulator of HLA II
INA internexin neuronal intermediate filament protein, alpha
INF2 inverted formin, FH2 and WH2 domain containing
ITGA10 integrin, alpha 10
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
KCTD20 potassium channel tetramerization domain containing 20
KIAA1107 KIAA1107
KIF17 kinesin family member 17
KLF13 Kruppel-like factor 13
LIMD2 LIM domain containing 2
LZTR1 leucine-zipper-like transcription regulator 1
MDM4 MDM4, p53 regulator
MLLT4-AS1 MLLT4 antisense RNA 1 (head to head)
MOCS3 molybdenum cofactor synthesis 3
MXD3 MAX dimerization protein 3
MYOZ3 myozenin 3
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NEUROD4 neuronal differentiation 4
NLK nemo-like kinase
NSUN6 NOP2/Sun domain family, member 6
NT5M 5',3'-nucleotidase, mitochondrial
OLAH oleoyl-ACP hydrolase
PARG poly (ADP-ribose) glycohydrolase
PARP16 poly (ADP-ribose) polymerase family, member 16
PCDHGA8 protocadherin gamma subfamily A, 8
PGP phosphoglycolate phosphatase
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PLD3 phospholipase D family, member 3
PLTP phospholipid transfer protein
PMFBP1 polyamine modulated factor 1 binding protein 1
POLM polymerase (DNA directed), mu
RAB23 RAB23, member RAS oncogene family
RAB3D RAB3D, member RAS oncogene family
RANBP17 RAN binding protein 17
REC8 REC8 meiotic recombination protein
RPL13P5 ribosomal protein L13 pseudogene 5
RPRD2 regulation of nuclear pre-mRNA domain containing 2
SLC35F6 solute carrier family 35, member F6
SYCP2 synaptonemal complex protein 2
TBL1Y transducin (beta)-like 1, Y-linked
TET3 tet methylcytosine dioxygenase 3
THRAP3 thyroid hormone receptor associated protein 3
TMEM180 transmembrane protein 180
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14
TPM3 tropomyosin 3
TRAF2 TNF receptor-associated factor 2
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TRPV2 transient receptor potential cation channel, subfamily V, member 2
TSC22D4 TSC22 domain family, member 4
TTC23 tetratricopeptide repeat domain 23
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
UPK3A uroplakin 3A
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF510 zinc finger protein 510
ZNF76 zinc finger protein 76