sulfametoxydiazine-6212 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the sulfametoxydiazine-6212 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABLIM3 actin binding LIM protein family, member 3
AKR1C1 aldo-keto reductase family 1, member C1
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ART1 ADP-ribosyltransferase 1
ASB1 ankyrin repeat and SOCS box containing 1
ATN1 atrophin 1
B9D1 B9 protein domain 1
BCAP29 B-cell receptor-associated protein 29
BTN2A1 butyrophilin, subfamily 2, member A1
CCDC28B coiled-coil domain containing 28B
CCKAR cholecystokinin A receptor
CD6 CD6 molecule
CDKN2A cyclin-dependent kinase inhibitor 2A
CEP68 centrosomal protein 68kDa
CRIP1 cysteine-rich protein 1 (intestinal)
CSE1L CSE1 chromosome segregation 1-like (yeast)
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1)
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
F8 coagulation factor VIII, procoagulant component
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
FLJ11292
FOXP3 forkhead box P3
FSCN1 fascin actin-bundling protein 1
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GAS2 growth arrest-specific 2
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GID4 GID complex subunit 4
GMIP GEM interacting protein
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GRK5 G protein-coupled receptor kinase 5
GRM8 glutamate receptor, metabotropic 8
GTPBP4 GTP binding protein 4
HLA-DOA major histocompatibility complex, class II, DO alpha
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HOXD1 homeobox D1
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KIAA0930 KIAA0930
LAMC3 laminin, gamma 3
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAP4 microtubule-associated protein 4
MBNL2 muscleblind-like splicing regulator 2
MED15 mediator complex subunit 15
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
MTA1 metastasis associated 1
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MYLK myosin light chain kinase
MYO1F myosin IF
N4BP1 NEDD4 binding protein 1
NBL1 neuroblastoma 1, DAN family BMP antagonist
NCR2 natural cytotoxicity triggering receptor 2
NF2 neurofibromin 2 (merlin)
NNAT neuronatin
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
NR4A1 nuclear receptor subfamily 4, group A, member 1
OR7A10 olfactory receptor, family 7, subfamily A, member 10
PDE3B phosphodiesterase 3B, cGMP-inhibited
PHF20 PHD finger protein 20
PLAA phospholipase A2-activating protein
PLAU plasminogen activator, urokinase
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PRKCA protein kinase C, alpha
PTCRA pre T-cell antigen receptor alpha
PTPN21 protein tyrosine phosphatase, non-receptor type 21
R3HCC1L R3H domain and coiled-coil containing 1-like
RAB11B RAB11B, member RAS oncogene family
RAD23B RAD23 homolog B (S. cerevisiae)
RARG retinoic acid receptor, gamma
RCN3 reticulocalbin 3, EF-hand calcium binding domain
RFTN1 raftlin, lipid raft linker 1
RNASEH2B ribonuclease H2, subunit B
SAMD4A sterile alpha motif domain containing 4A
SCN10A sodium channel, voltage gated, type X alpha subunit
SCN1B sodium channel, voltage gated, type I beta subunit
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SH3BP2 SH3-domain binding protein 2
SIPA1L3 signal-induced proliferation-associated 1 like 3
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SNED1 sushi, nidogen and EGF-like domains 1
SPAG8 sperm associated antigen 8
SPRY2 sprouty homolog 2 (Drosophila)
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
SYNGR1 synaptogyrin 1
TAOK2 TAO kinase 2
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TBX10 T-box 10
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TRIM2 tripartite motif containing 2
USB1 U6 snRNA biogenesis 1
VPRBP Vpr (HIV-1) binding protein
XYLT2 xylosyltransferase II
ZHX3 zinc fingers and homeoboxes 3
ZNF335 zinc finger protein 335
ZNF783 zinc finger family member 783

decreased expression

Symbol Name
AGO1 argonaute RISC catalytic component 1
AKR1C3 aldo-keto reductase family 1, member C3
ANKRD36 ankyrin repeat domain 36
ARRB2 arrestin, beta 2
ATAD2B ATPase family, AAA domain containing 2B
BAX BCL2-associated X protein
BCL10 B-cell CLL/lymphoma 10
C11ORF95 chromosome 11 open reading frame 95
CAPG capping protein (actin filament), gelsolin-like
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCDC170 coiled-coil domain containing 170
CCNJ cyclin J
CFD complement factor D (adipsin)
CHMP6 charged multivesicular body protein 6
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CLDN4 claudin 4
CXORF56 chromosome X open reading frame 56
DCAF10 DDB1 and CUL4 associated factor 10
DCK deoxycytidine kinase
DEPTOR DEP domain containing MTOR-interacting protein
FAM160B2 family with sequence similarity 160, member B2
FAM188A family with sequence similarity 188, member A
FBXW12 F-box and WD repeat domain containing 12
FKBP10 FK506 binding protein 10, 65 kDa
FPGS folylpolyglutamate synthase
FZD4 frizzled class receptor 4
GAA glucosidase, alpha; acid
GDAP1 ganglioside induced differentiation associated protein 1
GIN1 gypsy retrotransposon integrase 1
GINS4 GINS complex subunit 4 (Sld5 homolog)
GLI3 GLI family zinc finger 3
GMEB1 glucocorticoid modulatory element binding protein 1
HIRA histone cell cycle regulator
HMG20A high mobility group 20A
INF2 inverted formin, FH2 and WH2 domain containing
IPO13 importin 13
JADE1 jade family PHD finger 1
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KDM5C lysine (K)-specific demethylase 5C
KIFC1 kinesin family member C1
KLHL2 kelch-like family member 2
KLHL21 kelch-like family member 21
KRBOX4 KRAB box domain containing 4
KRT13 keratin 13, type I
LMNB1 lamin B1
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LRRC16A leucine rich repeat containing 16A
MAP7D1 MAP7 domain containing 1
MCM9 minichromosome maintenance complex component 9
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MRPL19 mitochondrial ribosomal protein L19
MTMR11 myotubularin related protein 11
MXD3 MAX dimerization protein 3
NBEA neurobeachin
NHLRC2 NHL repeat containing 2
NR1H3 nuclear receptor subfamily 1, group H, member 3
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
OXTR oxytocin receptor
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLD3 phospholipase D family, member 3
POLI polymerase (DNA directed) iota
POTEKP POTE ankyrin domain family, member K, pseudogene
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
RIBC2 RIB43A domain with coiled-coils 2
RNF31 ring finger protein 31
SCYL2 SCY1-like 2 (S. cerevisiae)
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae)
SERTAD3 SERTA domain containing 3
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC46A3 solute carrier family 46, member 3
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SMYD5 SMYD family member 5
SNX15 sorting nexin 15
STARD13 StAR-related lipid transfer (START) domain containing 13
SUN2 Sad1 and UNC84 domain containing 2
SYT17 synaptotagmin XVII
TCTN1 tectonic family member 1
THOP1 thimet oligopeptidase 1
TPST2 tyrosylprotein sulfotransferase 2
TRAF5 TNF receptor-associated factor 5
TSPYL2 TSPY-like 2
UBXN8 UBX domain protein 8
USP18 ubiquitin specific peptidase 18
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VAV1 vav 1 guanine nucleotide exchange factor
YEATS4 YEATS domain containing 4
ZBTB10 zinc finger and BTB domain containing 10
ZNF165 zinc finger protein 165
ZNF211 zinc finger protein 211
ZNF232 zinc finger protein 232
ZNF562 zinc finger protein 562
ZNF652 zinc finger protein 652
ZNF768 zinc finger protein 768
ZNF83 zinc finger protein 83
ZNHIT2 zinc finger, HIT-type containing 2