sulfamonomethoxine-2742 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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195 genes differentially expressed following the sulfamonomethoxine-2742 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOXL acyl-CoA oxidase-like
ACTA2 actin, alpha 2, smooth muscle, aorta
ADRA1A adrenoceptor alpha 1A
AGXT alanine-glyoxylate aminotransferase
AKR1C4 aldo-keto reductase family 1, member C4
ANKEF1 ankyrin repeat and EF-hand domain containing 1
APOB apolipoprotein B
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
BTNL8 butyrophilin-like 8
C14ORF1 chromosome 14 open reading frame 1
C1ORF68 chromosome 1 open reading frame 68
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CACNB3 calcium channel, voltage-dependent, beta 3 subunit
CALD1 caldesmon 1
CD28 CD28 molecule
CD72 CD72 molecule
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDH4 cadherin 4, type 1, R-cadherin (retinal)
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CEMP1 cementum protein 1
COL1A1 collagen, type I, alpha 1
COL8A2 collagen, type VIII, alpha 2
CRH corticotropin releasing hormone
CSHL1 chorionic somatomammotropin hormone-like 1
CUEDC1 CUE domain containing 1
DPP4 dipeptidyl-peptidase 4
DSCAM Down syndrome cell adhesion molecule
EGOT eosinophil granule ontogeny transcript (non-protein coding)
FAM13C family with sequence similarity 13, member C
FGFR2 fibroblast growth factor receptor 2
FLJ21369 uncharacterized protein FLJ21369
FOXL1 forkhead box L1
GEM GTP binding protein overexpressed in skeletal muscle
GRK4 G protein-coupled receptor kinase 4
HAMP hepcidin antimicrobial peptide
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HOXD13 homeobox D13
HPSE2 heparanase 2 (inactive)
HR hair growth associated
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
HSPB6 heat shock protein, alpha-crystallin-related, B6
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IL1RL1 interleukin 1 receptor-like 1
IL1RN interleukin 1 receptor antagonist
JPH3 junctophilin 3
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1
KLHL22 kelch-like family member 22
LENEP lens epithelial protein
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MFSD6 major facilitator superfamily domain containing 6
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MTSS1 metastasis suppressor 1
MYO6 myosin VI
NRG1 neuregulin 1
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
OLFM4 olfactomedin 4
OLFML2A olfactomedin-like 2A
PADI4 peptidyl arginine deiminase, type IV
PAPOLB poly(A) polymerase beta (testis specific)
PAX8 paired box 8
PBOV1 prostate and breast cancer overexpressed 1
PCDHB17P protocadherin beta 17 pseudogene
POU1F1 POU class 1 homeobox 1
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A
PRDM12 PR domain containing 12
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
PTGIS prostaglandin I2 (prostacyclin) synthase
RUNDC3A RUN domain containing 3A
SCAND2P SCAN domain containing 2 pseudogene
SCIN scinderin
SIGLEC8 sialic acid binding Ig-like lectin 8
SIRPA signal-regulatory protein alpha
SIX3 SIX homeobox 3
SLC22A7 solute carrier family 22 (organic anion transporter), member 7
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SMG7-AS1 SMG7 antisense RNA 1
SOX2 SRY (sex determining region Y)-box 2
SPAG8 sperm associated antigen 8
SPRR1A small proline-rich protein 1A
SUGCT succinyl-CoA:glutarate-CoA transferase
SYT5 synaptotagmin V
TBKBP1 TBK1 binding protein 1
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TIMP3 TIMP metallopeptidase inhibitor 3
TMEM212 transmembrane protein 212
TMPRSS4 transmembrane protease, serine 4
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TRGV5 T cell receptor gamma variable 5
TRPM1 transient receptor potential cation channel, subfamily M, member 1
WISP3 WNT1 inducible signaling pathway protein 3
ZNF235 zinc finger protein 235
ZNF407 zinc finger protein 407
ZNF81 zinc finger protein 81

decreased expression

Symbol Name
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
AMDHD2 amidohydrolase domain containing 2
ANKH ANKH inorganic pyrophosphate transport regulator
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
BMP15 bone morphogenetic protein 15
C16ORF45 chromosome 16 open reading frame 45
C1ORF56 chromosome 1 open reading frame 56
C8ORF44 chromosome 8 open reading frame 44
CARF calcium responsive transcription factor
CCDC57 coiled-coil domain containing 57
CD300C CD300c molecule
CEP295 centrosomal protein 295kDa
CEP97 centrosomal protein 97kDa
CFP complement factor properdin
CHMP6 charged multivesicular body protein 6
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CLEC2D C-type lectin domain family 2, member D
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
DGKG diacylglycerol kinase, gamma 90kDa
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EFNA3 ephrin-A3
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
FKBP9 FK506 binding protein 9, 63 kDa
GK3P glycerol kinase 3 pseudogene
GMEB1 glucocorticoid modulatory element binding protein 1
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GNL1 guanine nucleotide binding protein-like 1
GPR22 G protein-coupled receptor 22
GRIP2 glutamate receptor interacting protein 2
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HIST1H1E histone cluster 1, H1e
HIST1H2BI histone cluster 1, H2bi
HIST1H3H histone cluster 1, H3h
IDI2-AS1 IDI2 antisense RNA 1
INCENP inner centromere protein antigens 135/155kDa
IQCG IQ motif containing G
KCTD20 potassium channel tetramerization domain containing 20
KCTD7 potassium channel tetramerization domain containing 7
KIAA0753 KIAA0753
KIF3C kinesin family member 3C
LIG4 ligase IV, DNA, ATP-dependent
LSP1 lymphocyte-specific protein 1
LYPLA2P1 lysophospholipase II pseudogene 1
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MDM4 MDM4, p53 regulator
MEP1B meprin A, beta
MVP major vault protein
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NCALD neurocalcin delta
NFE2L3 nuclear factor, erythroid 2-like 3
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NR1H3 nuclear receptor subfamily 1, group H, member 3
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PCBP4 poly(rC) binding protein 4
PDE6H phosphodiesterase 6H, cGMP-specific, cone, gamma
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PIR pirin (iron-binding nuclear protein)
PLA2G12A phospholipase A2, group XIIA
PLD3 phospholipase D family, member 3
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PRDM1 PR domain containing 1, with ZNF domain
PRICKLE3 prickle homolog 3 (Drosophila)
PYCRL pyrroline-5-carboxylate reductase-like
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
RHOH ras homolog family member H
RIN1 Ras and Rab interactor 1
RNF122 ring finger protein 122
RRAGB Ras-related GTP binding B
SCN10A sodium channel, voltage gated, type X alpha subunit
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
SYCP2 synaptonemal complex protein 2
SYNC syncoilin, intermediate filament protein
TCTN2 tectonic family member 2
TGFBR1 transforming growth factor, beta receptor 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM209 transmembrane protein 209
TMEM242 transmembrane protein 242
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14
TPM3 tropomyosin 3
TRIM25 tripartite motif containing 25
TRPS1 trichorhinophalangeal syndrome I
TSPYL2 TSPY-like 2
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VN1R1 vomeronasal 1 receptor 1
ZFHX4 zinc finger homeobox 4
ZNF177 zinc finger protein 177
ZNF225 zinc finger protein 225
ZNF254 zinc finger protein 254
ZNF34 zinc finger protein 34
ZNF492 zinc finger protein 492