sulfanilamide-2709 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the sulfanilamide-2709 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ADGRL1 adhesion G protein-coupled receptor L1
AGR2 anterior gradient 2
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
AREG amphiregulin
BMP8A bone morphogenetic protein 8a
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
C1S complement component 1, s subcomponent
CASC1 cancer susceptibility candidate 1
CAV2 caveolin 2
CCDC186 coiled-coil domain containing 186
CDC14B cell division cycle 14B
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CFAP70 cilia and flagella associated protein 70
CFP complement factor properdin
CLTA clathrin, light chain A
COL13A1 collagen, type XIII, alpha 1
COL6A2 collagen, type VI, alpha 2
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CRTAC1 cartilage acidic protein 1
CST6 cystatin E/M
DBT dihydrolipoamide branched chain transacylase E2
DDX28 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
DOLK dolichol kinase
EDA ectodysplasin A
ESR2 estrogen receptor 2 (ER beta)
FAM153A family with sequence similarity 153, member A
FAM49A family with sequence similarity 49, member A
FBLN1 fibulin 1
FBXL7 F-box and leucine-rich repeat protein 7
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
GPX7 glutathione peroxidase 7
H1F0 H1 histone family, member 0
HFE hemochromatosis
HIST1H3G histone cluster 1, H3g
HOXD1 homeobox D1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HPX hemopexin
HRG histidine-rich glycoprotein
HSF2BP heat shock transcription factor 2 binding protein
IDS iduronate 2-sulfatase
ITM2A integral membrane protein 2A
KLK3 kallikrein-related peptidase 3
LAMP1 lysosomal-associated membrane protein 1
LRP1 low density lipoprotein receptor-related protein 1
MATN1 matrilin 1, cartilage matrix protein
MBNL1 muscleblind-like splicing regulator 1
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NDN necdin, melanoma antigen (MAGE) family member
NF1 neurofibromin 1
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NTS neurotensin
OR1F2P olfactory receptor, family 1, subfamily F, member 2, pseudogene
PDCD6 programmed cell death 6
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PGAM2 phosphoglycerate mutase 2 (muscle)
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLSCR3 phospholipid scramblase 3
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
RIF1 replication timing regulatory factor 1
RNF186 ring finger protein 186
RTEL1 regulator of telomere elongation helicase 1
SCAMP5 secretory carrier membrane protein 5
SERHL2 serine hydrolase-like 2
SIGLEC7 sialic acid binding Ig-like lectin 7
SIM2 single-minded family bHLH transcription factor 2
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
SLCO4C1 solute carrier organic anion transporter family, member 4C1
SOCS3 suppressor of cytokine signaling 3
SPIN2A spindlin family, member 2A
SPINT2 serine peptidase inhibitor, Kunitz type, 2
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
SYNDIG1 synapse differentiation inducing 1
TBKBP1 TBK1 binding protein 1
TBX1 T-box 1
TBX5 T-box 5
TCP10 t-complex 10
TPSG1 tryptase gamma 1
TTC12 tetratricopeptide repeat domain 12
UBE2B ubiquitin-conjugating enzyme E2B
ULBP2 UL16 binding protein 2
VCX2 variable charge, X-linked 2
WNT16 wingless-type MMTV integration site family, member 16
WWP2 WW domain containing E3 ubiquitin protein ligase 2
XIST X inactive specific transcript (non-protein coding)
ZFYVE9 zinc finger, FYVE domain containing 9
ZKSCAN8 zinc finger with KRAB and SCAN domains 8
ZNF234 zinc finger protein 234
ZNF500 zinc finger protein 500
ZNF613 zinc finger protein 613

decreased expression

Symbol Name
ACADSB acyl-CoA dehydrogenase, short/branched chain
ACYP2 acylphosphatase 2, muscle type
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
AMDHD2 amidohydrolase domain containing 2
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ARMCX4 armadillo repeat containing, X-linked 4
ASB7 ankyrin repeat and SOCS box containing 7
ATAD2B ATPase family, AAA domain containing 2B
ATG9A autophagy related 9A
ATHL1 ATH1, acid trehalase-like 1 (yeast)
BTF3P12 basic transcription factor 3 pseudogene 12
C11ORF49 chromosome 11 open reading frame 49
C9ORF3 chromosome 9 open reading frame 3
CCDC132 coiled-coil domain containing 132
CCDC57 coiled-coil domain containing 57
CCDC71 coiled-coil domain containing 71
CCDC85C coiled-coil domain containing 85C
CCL4 chemokine (C-C motif) ligand 4
CLGN calmegin
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
CRELD1 cysteine-rich with EGF-like domains 1
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DNAL4 dynein, axonemal, light chain 4
DNM3 dynamin 3
ECI2 enoyl-CoA delta isomerase 2
FAM86C1 family with sequence similarity 86, member C1
FBXO3 F-box protein 3
FMOD fibromodulin
FRS3 fibroblast growth factor receptor substrate 3
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPC3 glypican 3
HDAC5 histone deacetylase 5
HHLA3 HERV-H LTR-associating 3
HIST1H2AI histone cluster 1, H2ai
IDI2-AS1 IDI2 antisense RNA 1
IFNA14 interferon, alpha 14
INA internexin neuronal intermediate filament protein, alpha
ITGA10 integrin, alpha 10
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KIAA1107 KIAA1107
KIF17 kinesin family member 17
KLF3 Kruppel-like factor 3 (basic)
KLHL36 kelch-like family member 36
LYPLA2P1 lysophospholipase II pseudogene 1
MTCP1 mature T-cell proliferation 1
NAG18 NAG18 mRNA
NCS1 neuronal calcium sensor 1
NECAB3 N-terminal EF-hand calcium binding protein 3
NOL10 nucleolar protein 10
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PCDHGA8 protocadherin gamma subfamily A, 8
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PHC1 polyhomeotic homolog 1 (Drosophila)
PKD2L2 polycystic kidney disease 2-like 2
PLA2G1B phospholipase A2, group IB (pancreas)
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PPDPF pancreatic progenitor cell differentiation and proliferation factor
PRF1 perforin 1 (pore forming protein)
PROS1 protein S (alpha)
PRSS53 protease, serine, 53
RAB23 RAB23, member RAS oncogene family
RCAN3 RCAN family member 3
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RHOBTB1 Rho-related BTB domain containing 1
SCN10A sodium channel, voltage gated, type X alpha subunit
SERGEF secretion regulating guanine nucleotide exchange factor
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SH3GLB2 SH3-domain GRB2-like endophilin B2
SLC12A8 solute carrier family 12, member 8
SLC16A6 solute carrier family 16, member 6
SPATA1 spermatogenesis associated 1
ST8SIA5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
STX11 syntaxin 11
TBL1Y transducin (beta)-like 1, Y-linked
TBX19 T-box 19
TMC5 transmembrane channel-like 5
TMEM120B transmembrane protein 120B
TRDMT1 tRNA aspartic acid methyltransferase 1
TRPS1 trichorhinophalangeal syndrome I
TSPAN13 tetraspanin 13
TUBA3C tubulin, alpha 3c
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
UPK3A uroplakin 3A
UPP1 uridine phosphorylase 1
VASH1 vasohibin 1
WASF3 WAS protein family, member 3
YPEL1 yippee-like 1 (Drosophila)
ZNF276 zinc finger protein 276
ZNF506 zinc finger protein 506
ZNF701 zinc finger protein 701
ZNF768 zinc finger protein 768