sulfanilamide-4474 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the sulfanilamide-4474 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ADCK2 aarF domain containing kinase 2
ANGPTL4 angiopoietin-like 4
APAF1 apoptotic peptidase activating factor 1
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
ATHL1 ATH1, acid trehalase-like 1 (yeast)
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BEAN1 brain expressed, associated with NEDD4, 1
BTNL2 butyrophilin-like 2
CCDC71 coiled-coil domain containing 71
CCNK cyclin K
CD79B CD79b molecule, immunoglobulin-associated beta
CDK18 cyclin-dependent kinase 18
CHN2 chimerin 2
CIZ1 CDKN1A interacting zinc finger protein 1
COL7A1 collagen, type VII, alpha 1
COL9A3 collagen, type IX, alpha 3
CYTH3 cytohesin 3
DCHS1 dachsous cadherin-related 1
DCTN2 dynactin 2 (p50)
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DRD2 dopamine receptor D2
DST dystonin
DSTYK dual serine/threonine and tyrosine protein kinase
ECE1 endothelin converting enzyme 1
EIF3F eukaryotic translation initiation factor 3, subunit F
ELOVL2 ELOVL fatty acid elongase 2
ENG endoglin
EPAS1 endothelial PAS domain protein 1
ESRRG estrogen-related receptor gamma
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
ETV1 ets variant 1
ETV6 ets variant 6
FGF18 fibroblast growth factor 18
FLRT2 fibronectin leucine rich transmembrane protein 2
FN1 fibronectin 1
FOXF1 forkhead box F1
FRK fyn-related Src family tyrosine kinase
FSHB follicle stimulating hormone, beta polypeptide
FYB FYN binding protein
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GLE1 GLE1 RNA export mediator
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GPATCH4 G patch domain containing 4
GRIK5 glutamate receptor, ionotropic, kainate 5
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HIST1H2AK histone cluster 1, H2ak
HSPA1L heat shock 70kDa protein 1-like
ICOSLG inducible T-cell co-stimulator ligand
IKZF1 IKAROS family zinc finger 1 (Ikaros)
INVS inversin
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KITLG KIT ligand
KLHL22 kelch-like family member 22
KRT19P2 keratin 19 pseudogene 2
LAMA2 laminin, alpha 2
LEFTY1 left-right determination factor 1
MAP7D3 MAP7 domain containing 3
MCF2L MCF.2 cell line derived transforming sequence-like
MDFI MyoD family inhibitor
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP3 matrix metallopeptidase 3
MOCS1 molybdenum cofactor synthesis 1
OAZ3 ornithine decarboxylase antizyme 3
PDCD2 programmed cell death 2
PDLIM4 PDZ and LIM domain 4
PDPN podoplanin
PEX16 peroxisomal biogenesis factor 16
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLCG1 phospholipase C, gamma 1
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1
PTPRU protein tyrosine phosphatase, receptor type, U
PYY peptide YY
RBMS2 RNA binding motif, single stranded interacting protein 2
RUNX1 runt-related transcription factor 1
SERHL2 serine hydrolase-like 2
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SLC22A6 solute carrier family 22 (organic anion transporter), member 6
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SPRR2C small proline-rich protein 2C (pseudogene)
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
TAOK2 TAO kinase 2
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
THRB thyroid hormone receptor, beta
TNNT2 troponin T type 2 (cardiac)
TNS1 tensin 1
TTLL3 tubulin tyrosine ligase-like family member 3
TTLL4 tubulin tyrosine ligase-like family member 4
VAV2 vav 2 guanine nucleotide exchange factor
XAF1 XIAP associated factor 1
ZNF44 zinc finger protein 44
ZNF528 zinc finger protein 528
ZSCAN2 zinc finger and SCAN domain containing 2

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
AGMAT agmatine ureohydrolase (agmatinase)
AK5 adenylate kinase 5
ANG angiogenin, ribonuclease, RNase A family, 5
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ARMCX4 armadillo repeat containing, X-linked 4
ATAD5 ATPase family, AAA domain containing 5
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
C1ORF105 chromosome 1 open reading frame 105
CCL27 chemokine (C-C motif) ligand 27
CCP110 centriolar coiled coil protein 110kDa
CDHR2 cadherin-related family member 2
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEMIP cell migration inducing protein, hyaluronan binding
CEP295 centrosomal protein 295kDa
CLCN6 chloride channel, voltage-sensitive 6
CLSPN claspin
CNTNAP3B contactin associated protein-like 3B
CRYBA2 crystallin, beta A2
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
ERMAP erythroblast membrane-associated protein (Scianna blood group)
EVPL envoplakin
EYA4 EYA transcriptional coactivator and phosphatase 4
FANCF Fanconi anemia, complementation group F
FBXL15 F-box and leucine-rich repeat protein 15
FBXL7 F-box and leucine-rich repeat protein 7
GALT galactose-1-phosphate uridylyltransferase
GMPR guanosine monophosphate reductase
GPATCH3 G patch domain containing 3
GRAMD4 GRAM domain containing 4
GRWD1 glutamate-rich WD repeat containing 1
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
GUSBP3 glucuronidase, beta pseudogene 3
HDAC7 histone deacetylase 7
HIST1H2AI histone cluster 1, H2ai
HIST1H3C histone cluster 1, H3c
HIST1H3G histone cluster 1, H3g
HIST1H4C histone cluster 1, H4c
IFI6 interferon, alpha-inducible protein 6
IFT54 intraflagellar transport 54
INO80D INO80 complex subunit D
IQSEC2 IQ motif and Sec7 domain 2
IRF1 interferon regulatory factor 1
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIRREL kin of IRRE like (Drosophila)
KIZ kizuna centrosomal protein
LIPG lipase, endothelial
LMTK1 lemur tail kinase 1
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LY86 lymphocyte antigen 86
MRPL44 mitochondrial ribosomal protein L44
MTMR6 myotubularin related protein 6
MUC3A mucin 3A, cell surface associated
NAT6 N-acetyltransferase 6 (GCN5-related)
NPIPB15 nuclear pore complex interacting protein family, member B15
NR1H2 nuclear receptor subfamily 1, group H, member 2
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PADI1 peptidyl arginine deiminase, type I
PARD6A par-6 family cell polarity regulator alpha
PER3 period circadian clock 3
PLEKHO1 pleckstrin homology domain containing, family O member 1
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRKX protein kinase, X-linked
PTK6 protein tyrosine kinase 6
REPS2 RALBP1 associated Eps domain containing 2
RHOBTB2 Rho-related BTB domain containing 2
RIBC2 RIB43A domain with coiled-coils 2
RNF2 ring finger protein 2
S100A3 S100 calcium binding protein A3
SHROOM2 shroom family member 2
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC46A3 solute carrier family 46, member 3
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SPEG SPEG complex locus
TEX15 testis expressed 15
TM6SF1 transmembrane 6 superfamily member 1
TMOD3 tropomodulin 3 (ubiquitous)
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TUBA3C tubulin, alpha 3c
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
VEZT vezatin, adherens junctions transmembrane protein
WNT7A wingless-type MMTV integration site family, member 7A
ZNF160 zinc finger protein 160
ZNF214 zinc finger protein 214