sulfaphenazole-1673 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the sulfaphenazole-1673 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ADCY9 adenylate cyclase 9
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ATP11A ATPase, class VI, type 11A
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
B9D1 B9 protein domain 1
BAIAP2 BAI1-associated protein 2
BTF3P12 basic transcription factor 3 pseudogene 12
C19ORF73 chromosome 19 open reading frame 73
C20ORF27 chromosome 20 open reading frame 27
C21ORF2 chromosome 21 open reading frame 2
CA4 carbonic anhydrase IV
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CD82 CD82 molecule
CDC37 cell division cycle 37
CEP104 centrosomal protein 104kDa
CNTN1 contactin 1
CRABP1 cellular retinoic acid binding protein 1
DCAF8 DDB1 and CUL4 associated factor 8
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
DGKZ diacylglycerol kinase, zeta
DMWD dystrophia myotonica, WD repeat containing
DOCK4 dedicator of cytokinesis 4
DTX2 deltex 2, E3 ubiquitin ligase
E2F1 E2F transcription factor 1
ELK1 ELK1, member of ETS oncogene family
EMID1 EMI domain containing 1
FAM49B family with sequence similarity 49, member B
FBXL15 F-box and leucine-rich repeat protein 15
FKBP10 FK506 binding protein 10, 65 kDa
G6PC3 glucose 6 phosphatase, catalytic, 3
GAMT guanidinoacetate N-methyltransferase
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
GLP1R glucagon-like peptide 1 receptor
GOSR2 golgi SNAP receptor complex member 2
GPR143 G protein-coupled receptor 143
HDAC5 histone deacetylase 5
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
INADL InaD-like (Drosophila)
ING1 inhibitor of growth family, member 1
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1
KDM4C lysine (K)-specific demethylase 4C
KIAA0319L KIAA0319-like
KMT2A lysine (K)-specific methyltransferase 2A
KRIT1 KRIT1, ankyrin repeat containing
LAMC2 laminin, gamma 2
LMF2 lipase maturation factor 2
LMNB1 lamin B1
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MARS methionyl-tRNA synthetase
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MCOLN3 mucolipin 3
MST1L macrophage stimulating 1-like
MUC5B mucin 5B, oligomeric mucus/gel-forming
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NCALD neurocalcin delta
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
PAOX polyamine oxidase (exo-N4-amino)
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PCDHB13 protocadherin beta 13
PLEC plectin
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PSD4 pleckstrin and Sec7 domain containing 4
RARA retinoic acid receptor, alpha
RIN2 Ras and Rab interactor 2
RND2 Rho family GTPase 2
RPL23AP32 ribosomal protein L23a pseudogene 32
RPUSD2 RNA pseudouridylate synthase domain containing 2
S100A11 S100 calcium binding protein A11
SAFB2 scaffold attachment factor B2
SAYSD1 SAYSVFN motif domain containing 1
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SMAD3 SMAD family member 3
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SMC1A structural maintenance of chromosomes 1A
SPINK5 serine peptidase inhibitor, Kazal type 5
STX7 syntaxin 7
SYK spleen tyrosine kinase
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
TEAD3 TEA domain family member 3
TMEM184C transmembrane protein 184C
TPMT thiopurine S-methyltransferase
UBOX5 U-box domain containing 5
UNC45A unc-45 homolog A (C. elegans)
USP48 ubiquitin specific peptidase 48
WDR25 WD repeat domain 25
WFDC2 WAP four-disulfide core domain 2
WWTR1 WW domain containing transcription regulator 1
ZBTB48 zinc finger and BTB domain containing 48
ZCCHC24 zinc finger, CCHC domain containing 24
ZNF324 zinc finger protein 324
ZNF552 zinc finger protein 552

decreased expression

Symbol Name
AHDC1 AT hook, DNA binding motif, containing 1
ANKRD11 ankyrin repeat domain 11
ANKRD36B ankyrin repeat domain 36B
BAX BCL2-associated X protein
CCDC15 coiled-coil domain containing 15
CCNT1 cyclin T1
CENPJ centromere protein J
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
DACH1 dachshund family transcription factor 1
DCAF16 DDB1 and CUL4 associated factor 16
DCLRE1A DNA cross-link repair 1A
DNAL4 dynein, axonemal, light chain 4
DSCAM Down syndrome cell adhesion molecule
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EPHA4 EPH receptor A4
EPPK1 epiplakin 1
FGD6 FYVE, RhoGEF and PH domain containing 6
FICD FIC domain containing
FKBP14 FK506 binding protein 14, 22 kDa
FLT4 fms-related tyrosine kinase 4
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GBP2 guanylate binding protein 2, interferon-inducible
GINS4 GINS complex subunit 4 (Sld5 homolog)
GLI3 GLI family zinc finger 3
GMEB1 glucocorticoid modulatory element binding protein 1
GPR87 G protein-coupled receptor 87
GTPBP8 GTP-binding protein 8 (putative)
GUSBP3 glucuronidase, beta pseudogene 3
HELLS helicase, lymphoid-specific
HIST1H2AJ histone cluster 1, H2aj
HIST1H4C histone cluster 1, H4c
HP1BP3 heterochromatin protein 1, binding protein 3
IFT22 intraflagellar transport 22
IPP intracisternal A particle-promoted polypeptide
IRF2BP1 interferon regulatory factor 2 binding protein 1
IRF7 interferon regulatory factor 7
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
KIAA0894 KIAA0894 protein
KIF3A kinesin family member 3A
KIFC1 kinesin family member C1
KLK5 kallikrein-related peptidase 5
LYRM2 LYR motif containing 2
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAGT1 magnesium transporter 1
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MED1 mediator complex subunit 1
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MITF microphthalmia-associated transcription factor
MMP9 matrix metallopeptidase 9
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NPFFR1 neuropeptide FF receptor 1
NR1D2 nuclear receptor subfamily 1, group D, member 2
PCYOX1 prenylcysteine oxidase 1
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
POLH polymerase (DNA directed), eta
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PTCD2 pentatricopeptide repeat domain 2
PTER phosphotriesterase related
RAB3A RAB3A, member RAS oncogene family
RBBP5 retinoblastoma binding protein 5
RBM42 RNA binding motif protein 42
SH3BGR SH3 domain binding glutamate-rich protein
SLC16A6 solute carrier family 16, member 6
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC38A1 solute carrier family 38, member 1
SMCO4 single-pass membrane protein with coiled-coil domains 4
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SNORA21 small nucleolar RNA, H/ACA box 21
SOX12 SRY (sex determining region Y)-box 12
SPIN1 spindlin 1
SYNJ2BP synaptojanin 2 binding protein
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TIPRL TOR signaling pathway regulator
TMEM260 transmembrane protein 260
TRIM25 tripartite motif containing 25
TRIM66 tripartite motif containing 66
UBE2W ubiquitin-conjugating enzyme E2W (putative)
UGCG UDP-glucose ceramide glucosyltransferase
UNKL unkempt family zinc finger-like
WWC2 WW and C2 domain containing 2
ZBTB38 zinc finger and BTB domain containing 38
ZC2HC1A zinc finger, C2HC-type containing 1A
ZNF12 zinc finger protein 12
ZNF124 zinc finger protein 124
ZNF14 zinc finger protein 14
ZNF141 zinc finger protein 141
ZNF148 zinc finger protein 148
ZNF573 zinc finger protein 573
ZNF654 zinc finger protein 654
ZNF668 zinc finger protein 668
ZNF91 zinc finger protein 91
ZXDC ZXD family zinc finger C