sulfaphenazole-1794 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the sulfaphenazole-1794 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ACTG1 actin gamma 1
APP amyloid beta (A4) precursor protein
ARHGAP10 Rho GTPase activating protein 10
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1
ATP7A ATPase, Cu++ transporting, alpha polypeptide
BAG4 BCL2-associated athanogene 4
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C1ORF35 chromosome 1 open reading frame 35
C1QTNF1 C1q and tumor necrosis factor related protein 1
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CCP110 centriolar coiled coil protein 110kDa
CHD1L chromodomain helicase DNA binding protein 1-like
CHIC2 cysteine-rich hydrophobic domain 2
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
CNOT4 CCR4-NOT transcription complex, subunit 4
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous)
CRTC1 CREB regulated transcription coactivator 1
CXCL8 chemokine (C-X-C motif) ligand 8
CYB561 cytochrome b561
CYHR1 cysteine/histidine-rich 1
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4
ENO1 enolase 1, (alpha)
ESR1 estrogen receptor 1
EVPL envoplakin
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GON4L gon-4-like (C. elegans)
GTDC1 glycosyltransferase-like domain containing 1
H1F0 H1 histone family, member 0
H2AFX H2A histone family, member X
HMGB1 high mobility group box 1
HMOX2 heme oxygenase 2
HOMER3 homer scaffolding protein 3
HOXB9 homeobox B9
HSPD1 heat shock 60kDa protein 1 (chaperonin)
IL1RAP interleukin 1 receptor accessory protein
IQCK IQ motif containing K
IRAK4 interleukin-1 receptor-associated kinase 4
KIAA1549L KIAA1549-like
KIFC1 kinesin family member C1
KLHL3 kelch-like family member 3
KMT2A lysine (K)-specific methyltransferase 2A
LRP6 low density lipoprotein receptor-related protein 6
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LYPD3 LY6/PLAUR domain containing 3
MAGEA6 melanoma antigen family A6
MAPKAPK5-AS1 MAPKAPK5 antisense RNA 1
MED6 mediator complex subunit 6
NPEPL1 aminopeptidase-like 1
NPM3 nucleophosmin/nucleoplasmin 3
NR1H3 nuclear receptor subfamily 1, group H, member 3
NR2C1 nuclear receptor subfamily 2, group C, member 1
OCRL oculocerebrorenal syndrome of Lowe
OSBPL2 oxysterol binding protein-like 2
PCDH1 protocadherin 1
PEX1 peroxisomal biogenesis factor 1
PICALM phosphatidylinositol binding clathrin assembly protein
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLD2 phospholipase D2
PLXND1 plexin D1
POMT2 protein-O-mannosyltransferase 2
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1)
PRR5 proline rich 5 (renal)
PTPRR protein tyrosine phosphatase, receptor type, R
RAB1A RAB1A, member RAS oncogene family
RARS arginyl-tRNA synthetase
RBL2 retinoblastoma-like 2
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
RPL23 ribosomal protein L23
RPS3 ribosomal protein S3
SCN10A sodium channel, voltage gated, type X alpha subunit
SFTPB surfactant protein B
SIRT7 sirtuin 7
SMC1A structural maintenance of chromosomes 1A
SPHK2 sphingosine kinase 2
SRSF1 serine/arginine-rich splicing factor 1
SUB1 SUB1 homolog (S. cerevisiae)
TBC1D4 TBC1 domain family, member 4
TEX261 testis expressed 261
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TPT1 tumor protein, translationally-controlled 1
TRA2B transformer 2 beta homolog (Drosophila)
TRAFD1 TRAF-type zinc finger domain containing 1
TSPAN8 tetraspanin 8
UBOX5 U-box domain containing 5
USF2 upstream transcription factor 2, c-fos interacting
UTRN utrophin
WHSC1 Wolf-Hirschhorn syndrome candidate 1
ZBTB44 zinc finger and BTB domain containing 44
ZDHHC17 zinc finger, DHHC-type containing 17
ZFP36L1 ZFP36 ring finger protein-like 1
ZNF215 zinc finger protein 215
ZNF770 zinc finger protein 770
ZNF84 zinc finger protein 84

decreased expression

Symbol Name
ACOX2 acyl-CoA oxidase 2, branched chain
AHDC1 AT hook, DNA binding motif, containing 1
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARMC6 armadillo repeat containing 6
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
BCCIP BRCA2 and CDKN1A interacting protein
BIRC3 baculoviral IAP repeat containing 3
BPGM 2,3-bisphosphoglycerate mutase
BRIX1 BRX1, biogenesis of ribosomes
BSPRY B-box and SPRY domain containing
C7ORF43 chromosome 7 open reading frame 43
CCDC25 coiled-coil domain containing 25
CCDC94 coiled-coil domain containing 94
CCNE1 cyclin E1
CDC42BPB CDC42 binding protein kinase beta (DMPK-like)
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase
CENPB centromere protein B, 80kDa
CFD complement factor D (adipsin)
CHKB choline kinase beta
CLSPN claspin
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CROT carnitine O-octanoyltransferase
CRYL1 crystallin, lambda 1
CUTC cutC copper transporter
CXORF56 chromosome X open reading frame 56
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DAAM1 dishevelled associated activator of morphogenesis 1
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
FBXO46 F-box protein 46
GMIP GEM interacting protein
GSTZ1 glutathione S-transferase zeta 1
HELZ helicase with zinc finger
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
ICE2 interactor of little elongation complex ELL subunit 2
IL17RA interleukin 17 receptor A
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITPKB inositol-trisphosphate 3-kinase B
JUNB jun B proto-oncogene
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KIAA0513 KIAA0513
KIAA0894 KIAA0894 protein
KLF7 Kruppel-like factor 7 (ubiquitous)
KLHL26 kelch-like family member 26
LY6E lymphocyte antigen 6 complex, locus E
MAP1S microtubule-associated protein 1S
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MTERF1 mitochondrial transcription termination factor 1
MX1 MX dynamin-like GTPase 1
MXD3 MAX dimerization protein 3
MYO1D myosin ID
NABP2 nucleic acid binding protein 2
NR1D2 nuclear receptor subfamily 1, group D, member 2
NR1H2 nuclear receptor subfamily 1, group H, member 2
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic)
PARD6A par-6 family cell polarity regulator alpha
PELI1 pellino E3 ubiquitin protein ligase 1
PIGH phosphatidylinositol glycan anchor biosynthesis, class H
PJA2 praja ring finger 2, E3 ubiquitin protein ligase
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PPL periplakin
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
RAB33B RAB33B, member RAS oncogene family
RAB4B RAB4B, member RAS oncogene family
RCAN3 RCAN family member 3
RGS20 regulator of G-protein signaling 20
RNF25 ring finger protein 25
RPS17P5 ribosomal protein S17 pseudogene 5
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SCAMP4 secretory carrier membrane protein 4
SERTAD3 SERTA domain containing 3
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SMA4 glucuronidase, beta pseudogene
SMYD5 SMYD family member 5
SNIP1 Smad nuclear interacting protein 1
SOAT1 sterol O-acyltransferase 1
SPATA2L spermatogenesis associated 2-like
STBD1 starch binding domain 1
SUGCT succinyl-CoA:glutarate-CoA transferase
SUGP1 SURP and G patch domain containing 1
SYNC syncoilin, intermediate filament protein
TCTN1 tectonic family member 1
TICAM1 toll-like receptor adaptor molecule 1
TMEM184C transmembrane protein 184C
TMUB2 transmembrane and ubiquitin-like domain containing 2
ZBTB10 zinc finger and BTB domain containing 10
ZMAT5 zinc finger, matrin-type 5
ZNF302 zinc finger protein 302
ZNF426 zinc finger protein 426
ZNF574 zinc finger protein 574
ZNF85 zinc finger protein 85