sulfaphenazole-1836 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the sulfaphenazole-1836 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
AP4S1 adaptor-related protein complex 4, sigma 1 subunit
ARHGAP10 Rho GTPase activating protein 10
ATF6B activating transcription factor 6 beta
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
ATXN3 ataxin 3
B9D1 B9 protein domain 1
CABP2 calcium binding protein 2
CAMKMT calmodulin-lysine N-methyltransferase
CAP2 CAP, adenylate cyclase-associated protein, 2 (yeast)
CC2D1A coiled-coil and C2 domain containing 1A
CD300C CD300c molecule
CDH10 cadherin 10, type 2 (T2-cadherin)
CDH8 cadherin 8, type 2
CFL1 cofilin 1 (non-muscle)
CROT carnitine O-octanoyltransferase
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DSTYK dual serine/threonine and tyrosine protein kinase
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
E2F4 E2F transcription factor 4, p107/p130-binding
ELP6 elongator acetyltransferase complex subunit 6
EML3 echinoderm microtubule associated protein like 3
ENC1 ectodermal-neural cortex 1 (with BTB domain)
EPHB6 EPH receptor B6
ERN2 endoplasmic reticulum to nucleus signaling 2
F5 coagulation factor V (proaccelerin, labile factor)
FKBP5 FK506 binding protein 5
FOLR1 folate receptor 1 (adult)
FXYD3 FXYD domain containing ion transport regulator 3
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GSTCD glutathione S-transferase, C-terminal domain containing
GSTM1 glutathione S-transferase mu 1
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HMGA2 high mobility group AT-hook 2
ICAM2 intercellular adhesion molecule 2
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IL12RB1 interleukin 12 receptor, beta 1
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KLF12 Kruppel-like factor 12
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
LAT2 linker for activation of T cells family, member 2
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LOC729164 hCG1732469
LPAR2 lysophosphatidic acid receptor 2
LPCAT3 lysophosphatidylcholine acyltransferase 3
MAN1C1 mannosidase, alpha, class 1C, member 1
MAP2K7 mitogen-activated protein kinase kinase 7
MARK4 MAP/microtubule affinity-regulating kinase 4
MKL1 megakaryoblastic leukemia (translocation) 1
MMP19 matrix metallopeptidase 19
MYH14 myosin, heavy chain 14, non-muscle
NCOA2 nuclear receptor coactivator 2
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NR6A1 nuclear receptor subfamily 6, group A, member 1
PAPPA2 pappalysin 2
PDE4DIP phosphodiesterase 4D interacting protein
PECR peroxisomal trans-2-enoyl-CoA reductase
PHKA2 phosphorylase kinase, alpha 2 (liver)
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
POM121 POM121 transmembrane nucleoporin
PRDX2 peroxiredoxin 2
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAP1GAP RAP1 GTPase activating protein
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
RBM5 RNA binding motif protein 5
RPS4Y1 ribosomal protein S4, Y-linked 1
RREB1 ras responsive element binding protein 1
SFTPC surfactant protein C
SIRT3 sirtuin 3
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC35A2 solute carrier family 35 (UDP-galactose transporter), member A2
SLC39A9 solute carrier family 39, member 9
SLCO4C1 solute carrier organic anion transporter family, member 4C1
SNAI2 snail family zinc finger 2
SP140 SP140 nuclear body protein
SPINT1 serine peptidase inhibitor, Kunitz type 1
SPN sialophorin
STS steroid sulfatase (microsomal), isozyme S
SUGP1 SURP and G patch domain containing 1
SWAP70 SWAP switching B-cell complex 70kDa subunit
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
TBCD tubulin folding cofactor D
TCF4 transcription factor 4
TJAP1 tight junction associated protein 1 (peripheral)
TRD T cell receptor delta locus
TSR3 TSR3, 20S rRNA accumulation, homolog (S. cerevisiae)
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
USF2 upstream transcription factor 2, c-fos interacting
VN1R1 vomeronasal 1 receptor 1
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae)
ZFHX2 zinc finger homeobox 2
ZNF668 zinc finger protein 668

decreased expression

Symbol Name
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
ALPK1 alpha-kinase 1
AMIGO2 adhesion molecule with Ig-like domain 2
ANKRD46 ankyrin repeat domain 46
ANXA3 annexin A3
ATG2A autophagy related 2A
BPGM 2,3-bisphosphoglycerate mutase
C1ORF109 chromosome 1 open reading frame 109
CAPN15 calpain 15
CCL20 chemokine (C-C motif) ligand 20
CDT1 chromatin licensing and DNA replication factor 1
CEL carboxyl ester lipase
CENPQ centromere protein Q
CENPT centromere protein T
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CINP cyclin-dependent kinase 2 interacting protein
CNPY3 canopy FGF signaling regulator 3
CRIP1 cysteine-rich protein 1 (intestinal)
CRTAP cartilage associated protein
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CTNNBL1 catenin, beta like 1
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DHRS9 dehydrogenase/reductase (SDR family) member 9
DHTKD1 dehydrogenase E1 and transketolase domain containing 1
DKK2 dickkopf WNT signaling pathway inhibitor 2
DNASE1L1 deoxyribonuclease I-like 1
ETV6 ets variant 6
FPGS folylpolyglutamate synthase
GPR65 G protein-coupled receptor 65
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
GTF3C3 general transcription factor IIIC, polypeptide 3, 102kDa
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa
HINFP histone H4 transcription factor
HIST1H2BH histone cluster 1, H2bh
HLA-J major histocompatibility complex, class I, J (pseudogene)
IFI35 interferon-induced protein 35
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IL18 interleukin 18
IMPACT impact RWD domain protein
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
JUNB jun B proto-oncogene
KIAA0586 KIAA0586
KIF23 kinesin family member 23
KPNA4 karyopherin alpha 4 (importin alpha 3)
LMAN1 lectin, mannose-binding, 1
LMAN2L lectin, mannose-binding 2-like
MAN2C1 mannosidase, alpha, class 2C, member 1
MAP1S microtubule-associated protein 1S
MAPK3 mitogen-activated protein kinase 3
MBIP MAP3K12 binding inhibitory protein 1
MECR mitochondrial trans-2-enoyl-CoA reductase
METTL8 methyltransferase like 8
MINPP1 multiple inositol-polyphosphate phosphatase 1
MPDU1 mannose-P-dolichol utilization defect 1
MTERF1 mitochondrial transcription termination factor 1
MTERF4 mitochondrial transcription termination factor 4
NABP2 nucleic acid binding protein 2
NARFL nuclear prelamin A recognition factor-like
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NPM3 nucleophosmin/nucleoplasmin 3
OCEL1 occludin/ELL domain containing 1
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PANK4 pantothenate kinase 4
PCMTD2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PES1 pescadillo ribosomal biogenesis factor 1
PHACTR4 phosphatase and actin regulator 4
PHC1 polyhomeotic homolog 1 (Drosophila)
POR P450 (cytochrome) oxidoreductase
PTRH2 peptidyl-tRNA hydrolase 2
PYGB phosphorylase, glycogen; brain
QPCT glutaminyl-peptide cyclotransferase
RAB5C RAB5C, member RAS oncogene family
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
SAMD9 sterile alpha motif domain containing 9
SCYL2 SCY1-like 2 (S. cerevisiae)
SEC31B SEC31 homolog B (S. cerevisiae)
SETD8 SET domain containing (lysine methyltransferase) 8
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SNHG20 small nucleolar RNA host gene 20
SNHG3 small nucleolar RNA host gene 3
SNORA21 small nucleolar RNA, H/ACA box 21
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila)
TCTA T-cell leukemia translocation altered
THAP11 THAP domain containing 11
TLR4 toll-like receptor 4
TRMT12 tRNA methyltransferase 12 homolog (S. cerevisiae)
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
UBQLN4 ubiquilin 4
UEVLD UEV and lactate/malate dehyrogenase domains
ZDHHC24 zinc finger, DHHC-type containing 24
ZMAT5 zinc finger, matrin-type 5
ZNF268 zinc finger protein 268
ZNF654 zinc finger protein 654