sulfaphenazole-5507 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the sulfaphenazole-5507 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD6 abhydrolase domain containing 6
ACPP acid phosphatase, prostate
ACTG2 actin, gamma 2, smooth muscle, enteric
ADGB androglobin
ADTRP androgen-dependent TFPI-regulating protein
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
ANGEL2 angel homolog 2 (Drosophila)
ANKRD6 ankyrin repeat domain 6
ARFRP1 ADP-ribosylation factor related protein 1
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ARID4B AT rich interactive domain 4B (RBP1-like)
BIN1 bridging integrator 1
C1ORF159 chromosome 1 open reading frame 159
C2 complement component 2
CDK3 cyclin-dependent kinase 3
CEP68 centrosomal protein 68kDa
COL19A1 collagen, type XIX, alpha 1
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CUL4B cullin 4B
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16
DSC2 desmocollin 2
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
ELOVL2 ELOVL fatty acid elongase 2
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EPHA3 EPH receptor A3
EVPL envoplakin
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FGF13 fibroblast growth factor 13
FGFR4 fibroblast growth factor receptor 4
GAL galanin/GMAP prepropeptide
GBP1 guanylate binding protein 1, interferon-inducible
GMPR guanosine monophosphate reductase
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GPM6B glycoprotein M6B
GPR176 G protein-coupled receptor 176
GSK3A glycogen synthase kinase 3 alpha
H2AFY H2A histone family, member Y
HIST1H1E histone cluster 1, H1e
HNMT histamine N-methyltransferase
HOXA10 homeobox A10
HOXB2 homeobox B2
IL1RAP interleukin 1 receptor accessory protein
IQCC IQ motif containing C
KIAA0368 KIAA0368
KLF3 Kruppel-like factor 3 (basic)
KLF6 Kruppel-like factor 6
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LRRC14 leucine rich repeat containing 14
MAPK8 mitogen-activated protein kinase 8
MCTP1 multiple C2 domains, transmembrane 1
MED6 mediator complex subunit 6
MMP25 matrix metallopeptidase 25
NPAT nuclear protein, ataxia-telangiectasia locus
NR4A1 nuclear receptor subfamily 4, group A, member 1
OR52A1 olfactory receptor, family 52, subfamily A, member 1
PART1 prostate androgen-regulated transcript 1 (non-protein coding)
PARVB parvin, beta
PHC1 polyhomeotic homolog 1 (Drosophila)
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
PLCD1 phospholipase C, delta 1
PQLC2 PQ loop repeat containing 2
QPCTL glutaminyl-peptide cyclotransferase-like
REC8 REC8 meiotic recombination protein
RIMS3 regulating synaptic membrane exocytosis 3
SGK2 serum/glucocorticoid regulated kinase 2
SIVA1 SIVA1, apoptosis-inducing factor
SLC16A4 solute carrier family 16, member 4
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SOS2 son of sevenless homolog 2 (Drosophila)
SOX2 SRY (sex determining region Y)-box 2
SP1 Sp1 transcription factor
SPTBN1 spectrin, beta, non-erythrocytic 1
STARD5 StAR-related lipid transfer (START) domain containing 5
STK17A serine/threonine kinase 17a
STRN3 striatin, calmodulin binding protein 3
STX7 syntaxin 7
SYBU syntabulin (syntaxin-interacting)
TICAM1 toll-like receptor adaptor molecule 1
TLK1 tousled-like kinase 1
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TMEM63A transmembrane protein 63A
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNRC6B trinucleotide repeat containing 6B
TRIL TLR4 interactor with leucine-rich repeats
TSPAN32 tetraspanin 32
TYRP1 tyrosinase-related protein 1
VN1R1 vomeronasal 1 receptor 1
VPS13B vacuolar protein sorting 13 homolog B (yeast)
WAPAL wings apart-like homolog (Drosophila)
WIZ widely interspaced zinc finger motifs
WSCD1 WSC domain containing 1
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZBTB44 zinc finger and BTB domain containing 44
ZMAT4 zinc finger, matrin-type 4
ZNF747 zinc finger protein 747
ZYX zyxin

decreased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
ADGRG2 adhesion G protein-coupled receptor G2
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
AP4M1 adaptor-related protein complex 4, mu 1 subunit
C17ORF70 chromosome 17 open reading frame 70
C8ORF60 chromosome 8 open reading frame 60
C9ORF9 chromosome 9 open reading frame 9
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCDC94 coiled-coil domain containing 94
CDON cell adhesion associated, oncogene regulated
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CHKB choline kinase beta
CLCF1 cardiotrophin-like cytokine factor 1
CLEC4E C-type lectin domain family 4, member E
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DOCK1 dedicator of cytokinesis 1
EFNA3 ephrin-A3
ELSPBP1 epididymal sperm binding protein 1
ETNK2 ethanolamine kinase 2
FAM204A family with sequence similarity 204, member A
FAM53B family with sequence similarity 53, member B
FBXL15 F-box and leucine-rich repeat protein 15
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FOSL1 FOS-like antigen 1
FURIN furin (paired basic amino acid cleaving enzyme)
FUZ fuzzy planar cell polarity protein
GAA glucosidase, alpha; acid
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
HIST1H1D histone cluster 1, H1d
HIST1H4D histone cluster 1, H4d
HIST1H4F histone cluster 1, H4f
HOXC10 homeobox C10
HS1BP3 HCLS1 binding protein 3
IL17RA interleukin 17 receptor A
IMPG2 interphotoreceptor matrix proteoglycan 2
IRF6 interferon regulatory factor 6
ITGA10 integrin, alpha 10
ITPKB inositol-trisphosphate 3-kinase B
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KIZ kizuna centrosomal protein
LAMA3 laminin, alpha 3
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LIN7B lin-7 homolog B (C. elegans)
LMO2 LIM domain only 2 (rhombotin-like 1)
MAP7D1 MAP7 domain containing 1
MAPKBP1 mitogen-activated protein kinase binding protein 1
MITF microphthalmia-associated transcription factor
MOGS mannosyl-oligosaccharide glucosidase
MRPL44 mitochondrial ribosomal protein L44
NIPAL2 NIPA-like domain containing 2
NKAIN1 Na+/K+ transporting ATPase interacting 1
NOL6 nucleolar protein 6 (RNA-associated)
NXPH4 neurexophilin 4
PADI1 peptidyl arginine deiminase, type I
PCDHGB5 protocadherin gamma subfamily B, 5
PDZRN3 PDZ domain containing ring finger 3
PGPEP1 pyroglutamyl-peptidase I
PLEKHO1 pleckstrin homology domain containing, family O member 1
POLH polymerase (DNA directed), eta
POR P450 (cytochrome) oxidoreductase
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PRSS22 protease, serine, 22
PVRL3 poliovirus receptor-related 3
RAB5B RAB5B, member RAS oncogene family
REM1 RAS (RAD and GEM)-like GTP-binding 1
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RFTN1 raftlin, lipid raft linker 1
RNF126P1 ring finger protein 126 pseudogene 1
RNF170 ring finger protein 170
RNF43 ring finger protein 43
RPL23AP32 ribosomal protein L23a pseudogene 32
SCN1B sodium channel, voltage gated, type I beta subunit
SIRT6 sirtuin 6
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TMEM8A transmembrane protein 8A
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TRAF2 TNF receptor-associated factor 2
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TUBA3C tubulin, alpha 3c
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
TWF2 twinfilin actin binding protein 2
WDR19 WD repeat domain 19
XAB2 XPA binding protein 2
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZFHX3 zinc finger homeobox 3
ZNF276 zinc finger protein 276
ZNF282 zinc finger protein 282
ZSCAN31 zinc finger and SCAN domain containing 31