sulfapyridine-2538 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the sulfapyridine-2538 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACVRL1 activin A receptor type II-like 1
AGFG2 ArfGAP with FG repeats 2
ANG angiogenin, ribonuclease, RNase A family, 5
APOF apolipoprotein F
ASPA aspartoacylase
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
BIN1 bridging integrator 1
BLZF1 basic leucine zipper nuclear factor 1
C1QTNF3 C1q and tumor necrosis factor related protein 3
C3ORF14 chromosome 3 open reading frame 14
CASKIN2 CASK interacting protein 2
CEMP1 cementum protein 1
CFP complement factor properdin
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
COL18A1 collagen, type XVIII, alpha 1
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa
CRY2 cryptochrome circadian clock 2
CUEDC1 CUE domain containing 1
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DCT dopachrome tautomerase
DMTN dematin actin binding protein
DUSP1 dual specificity phosphatase 1
EDDM3B epididymal protein 3B
EGR1 early growth response 1
EPHA4 EPH receptor A4
FGFR2 fibroblast growth factor receptor 2
FPR1 formyl peptide receptor 1
GBP2 guanylate binding protein 2, interferon-inducible
GJA4 gap junction protein, alpha 4, 37kDa
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GULP1 GULP, engulfment adaptor PTB domain containing 1
HCFC1 host cell factor C1
HIST1H2BJ histone cluster 1, H2bj
HLA-DRB4 major histocompatibility complex, class II, DR beta 4
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
ICAM5 intercellular adhesion molecule 5, telencephalin
IFNB1 interferon, beta 1, fibroblast
IFT22 intraflagellar transport 22
IGFBP5 insulin-like growth factor binding protein 5
ISYNA1 inositol-3-phosphate synthase 1
ITGB5 integrin, beta 5
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1
KIR2DS4 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4
KRTAP5-9 keratin associated protein 5-9
LPAR1 lysophosphatidic acid receptor 1
LSAMP limbic system-associated membrane protein
MMP19 matrix metallopeptidase 19
MSRB2 methionine sulfoxide reductase B2
MTSS1 metastasis suppressor 1
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NLRP1 NLR family, pyrin domain containing 1
NPTXR neuronal pentraxin receptor
NR0B1 nuclear receptor subfamily 0, group B, member 1
OLFML2A olfactomedin-like 2A
ONECUT1 one cut homeobox 1
PDE4D phosphodiesterase 4D, cAMP-specific
PEG10 paternally expressed 10
PLSCR3 phospholipid scramblase 3
PPP1R26 protein phosphatase 1, regulatory subunit 26
PRM2 protamine 2
PSD3 pleckstrin and Sec7 domain containing 3
RARA retinoic acid receptor, alpha
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1
RBMY2FP RNA binding motif protein, Y-linked, family 2, member F pseudogene
RDH5 retinol dehydrogenase 5 (11-cis/9-cis)
RHOD ras homolog family member D
RIMS3 regulating synaptic membrane exocytosis 3
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RPS4Y1 ribosomal protein S4, Y-linked 1
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
RUNDC3B RUN domain containing 3B
RYR2 ryanodine receptor 2 (cardiac)
SAA4 serum amyloid A4, constitutive
SFTPB surfactant protein B
SH3BP1 SH3-domain binding protein 1
SIGLEC8 sialic acid binding Ig-like lectin 8
SIGLEC9 sialic acid binding Ig-like lectin 9
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SMTN smoothelin
SNCG synuclein, gamma (breast cancer-specific protein 1)
SOX13 SRY (sex determining region Y)-box 13
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TEAD3 TEA domain family member 3
TMCC1 transmembrane and coiled-coil domain family 1
TMPRSS2 transmembrane protease, serine 2
TNK1 tyrosine kinase, non-receptor, 1
TRAPPC9 trafficking protein particle complex 9
TRGV5 T cell receptor gamma variable 5
TRIM23 tripartite motif containing 23
TSKU tsukushi, small leucine rich proteoglycan
TTC12 tetratricopeptide repeat domain 12
UMPS uridine monophosphate synthetase
ZNF280A zinc finger protein 280A
ZNF646 zinc finger protein 646
ZNF821 zinc finger protein 821
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ADAM15 ADAM metallopeptidase domain 15
BAG4 BCL2-associated athanogene 4
BPGM 2,3-bisphosphoglycerate mutase
C5 complement component 5
CBX4 chromobox homolog 4
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCDC106 coiled-coil domain containing 106
CD300C CD300c molecule
CDON cell adhesion associated, oncogene regulated
CEP83 centrosomal protein 83kDa
CHMP6 charged multivesicular body protein 6
CHPF chondroitin polymerizing factor
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
DEFB1 defensin, beta 1
DEPDC1 DEP domain containing 1
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DHRS11 dehydrogenase/reductase (SDR family) member 11
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
DNAL4 dynein, axonemal, light chain 4
ERN2 endoplasmic reticulum to nucleus signaling 2
F8 coagulation factor VIII, procoagulant component
FJX1 four jointed box 1 (Drosophila)
FOXN2 forkhead box N2
GAA glucosidase, alpha; acid
GDE1 glycerophosphodiester phosphodiesterase 1
GLTP glycolipid transfer protein
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPALPP1 GPALPP motifs containing 1
GSTCD glutathione S-transferase, C-terminal domain containing
HIST1H1E histone cluster 1, H1e
HIST1H3B histone cluster 1, H3b
HYMAI hydatidiform mole associated and imprinted (non-protein coding)
IL4R interleukin 4 receptor
INF2 inverted formin, FH2 and WH2 domain containing
ITPKB inositol-trisphosphate 3-kinase B
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KCNK5 potassium channel, two pore domain subfamily K, member 5
KCTD20 potassium channel tetramerization domain containing 20
KDM7A lysine (K)-specific demethylase 7A
KIF23 kinesin family member 23
KLF1 Kruppel-like factor 1 (erythroid)
KRT81 keratin 81, type II
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LIMD2 LIM domain containing 2
LIME1 Lck interacting transmembrane adaptor 1
LRRC41 leucine rich repeat containing 41
LYPLA2P1 lysophospholipase II pseudogene 1
MBTD1 mbt domain containing 1
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MRPL44 mitochondrial ribosomal protein L44
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NFS1 NFS1 cysteine desulfurase
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
OASL 2'-5'-oligoadenylate synthetase-like
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PIP prolactin-induced protein
PLA2G15 phospholipase A2, group XV
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
POM121 POM121 transmembrane nucleoporin
PPT2 palmitoyl-protein thioesterase 2
PROL1 proline rich, lacrimal 1
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PTGES2 prostaglandin E synthase 2
PWP2 PWP2 periodic tryptophan protein homolog (yeast)
QTRT1 queuine tRNA-ribosyltransferase 1
RNF122 ring finger protein 122
RNF126P1 ring finger protein 126 pseudogene 1
RNF25 ring finger protein 25
RRP1 ribosomal RNA processing 1
RUSC2 RUN and SH3 domain containing 2
SETD8 SET domain containing (lysine methyltransferase) 8
SIK1 salt-inducible kinase 1
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SURF2 surfeit 2
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TBL3 transducin (beta)-like 3
TRAPPC13 trafficking protein particle complex 13
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSPAN13 tetraspanin 13
TWISTNB TWIST neighbor
TXLNG taxilin gamma
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
VNN2 vanin 2
WDR91 WD repeat domain 91
ZBTB6 zinc finger and BTB domain containing 6
ZC3H12A zinc finger CCCH-type containing 12A
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF322P1 zinc finger protein 322 pseudogene 1