sulfapyridine-6101 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the sulfapyridine-6101 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAA2 acetyl-CoA acyltransferase 2
ACRV1 acrosomal vesicle protein 1
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
AKAP1 A kinase (PRKA) anchor protein 1
ALOX12 arachidonate 12-lipoxygenase
ANP32C acidic (leucine-rich) nuclear phosphoprotein 32 family, member C
ARC activity-regulated cytoskeleton-associated protein
ARHGAP26 Rho GTPase activating protein 26
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
C10ORF95 chromosome 10 open reading frame 95
CA14 carbonic anhydrase XIV
CD177 CD177 molecule
CD6 CD6 molecule
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDHR2 cadherin-related family member 2
CLUL1 clusterin-like 1 (retinal)
COL11A2 collagen, type XI, alpha 2
COL4A6 collagen, type IV, alpha 6
CPB2 carboxypeptidase B2 (plasma)
CRH corticotropin releasing hormone
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DAAM2 dishevelled associated activator of morphogenesis 2
DCX doublecortin
DGCR5 DiGeorge syndrome critical region gene 5 (non-protein coding)
DHRS12 dehydrogenase/reductase (SDR family) member 12
DNASE2B deoxyribonuclease II beta
EFS embryonal Fyn-associated substrate
EHD2 EH-domain containing 2
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
F2RL2 coagulation factor II (thrombin) receptor-like 2
FAM163A family with sequence similarity 163, member A
FSCN3 fascin actin-bundling protein 3, testicular
FXYD2 FXYD domain containing ion transport regulator 2
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GPR153 G protein-coupled receptor 153
GYPB glycophorin B (MNS blood group)
HMGN5 high mobility group nucleosome binding domain 5
HNF1B HNF1 homeobox B
HPSE2 heparanase 2 (inactive)
HR hair growth associated
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
IGFBP3 insulin-like growth factor binding protein 3
IGLJ3 immunoglobulin lambda joining 3
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
IGSF6 immunoglobulin superfamily, member 6
IZUMO4 IZUMO family member 4
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8
KLF13 Kruppel-like factor 13
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LECT1 leukocyte cell derived chemotaxin 1
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LOC157562 uncharacterized LOC157562
LY9 lymphocyte antigen 9
MID1 midline 1
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MMP25 matrix metallopeptidase 25
MOB3B MOB kinase activator 3B
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NDRG2 NDRG family member 2
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NKX2-5 NK2 homeobox 5
OR2B6 olfactory receptor, family 2, subfamily B, member 6
OSBPL10 oxysterol binding protein-like 10
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PAX6 paired box 6
PIGO phosphatidylinositol glycan anchor biosynthesis, class O
PKNOX2 PBX/knotted 1 homeobox 2
PML promyelocytic leukemia
PROX1 prospero homeobox 1
PRUNE2 prune homolog 2 (Drosophila)
RGS5 regulator of G-protein signaling 5
RTN2 reticulon 2
RUNX1 runt-related transcription factor 1
SAMD9 sterile alpha motif domain containing 9
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1
SLC38A3 solute carrier family 38, member 3
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SPAG16 sperm associated antigen 16
SPINK5 serine peptidase inhibitor, Kazal type 5
SRPK3 SRSF protein kinase 3
STMN4 stathmin-like 4
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TBX3 T-box 3
TCP11 t-complex 11, testis-specific
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TRAF3IP3 TRAF3 interacting protein 3
XAF1 XIAP associated factor 1
ZNF222 zinc finger protein 222
ZNF440 zinc finger protein 440
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
ADM adrenomedullin
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
C2ORF27A chromosome 2 open reading frame 27A
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC68 coiled-coil domain containing 68
CCP110 centriolar coiled coil protein 110kDa
CD34 CD34 molecule
CD83 CD83 molecule
CDK20 cyclin-dependent kinase 20
CHST10 carbohydrate sulfotransferase 10
CNTN1 contactin 1
CORO1A coronin, actin binding protein, 1A
CRELD1 cysteine-rich with EGF-like domains 1
CRY2 cryptochrome circadian clock 2
CSF1R colony stimulating factor 1 receptor
DIXDC1 DIX domain containing 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
ERN2 endoplasmic reticulum to nucleus signaling 2
ETNK2 ethanolamine kinase 2
FAM184A family with sequence similarity 184, member A
FAM198B family with sequence similarity 198, member B
FMOD fibromodulin
FRMPD1 FERM and PDZ domain containing 1
FSTL3 follistatin-like 3 (secreted glycoprotein)
GAN gigaxonin
GAS2 growth arrest-specific 2
GPATCH3 G patch domain containing 3
GPRIN2 G protein regulated inducer of neurite outgrowth 2
HAMP hepcidin antimicrobial peptide
HDAC5 histone deacetylase 5
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIST1H1D histone cluster 1, H1d
HOXC10 homeobox C10
HSPA1L heat shock 70kDa protein 1-like
IGFBP6 insulin-like growth factor binding protein 6
IL22 interleukin 22
INO80D INO80 complex subunit D
IQSEC2 IQ motif and Sec7 domain 2
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6
KDM7A lysine (K)-specific demethylase 7A
KIF13A kinesin family member 13A
LAMA5 laminin, alpha 5
LHX1 LIM homeobox 1
LINC01587 long intergenic non-protein coding RNA 1587
LOC390998 ribosomal protein L10 pseudogene
LRP5L low density lipoprotein receptor-related protein 5-like
LZTS3 leucine zipper, putative tumor suppressor family member 3
MALL mal, T-cell differentiation protein-like
MBNL3 muscleblind-like splicing regulator 3
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MVD mevalonate (diphospho) decarboxylase
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
NOD1 nucleotide-binding oligomerization domain containing 1
NT5E 5'-nucleotidase, ecto (CD73)
PACS1 phosphofurin acidic cluster sorting protein 1
PCDHA9 protocadherin alpha 9
PDGFD platelet derived growth factor D
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PLAU plasminogen activator, urokinase
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLCD1 phospholipase C, delta 1
QPCT glutaminyl-peptide cyclotransferase
QPCTL glutaminyl-peptide cyclotransferase-like
RAB40AL RAB40A, member RAS oncogene family-like
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RHBDD3 rhomboid domain containing 3
RNF39 ring finger protein 39
RPAP1 RNA polymerase II associated protein 1
SDC3 syndecan 3
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SIX1 SIX homeobox 1
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TGFBR1 transforming growth factor, beta receptor 1
TGFBR3 transforming growth factor, beta receptor III
TM6SF1 transmembrane 6 superfamily member 1
TMEM209 transmembrane protein 209
TRIM36 tripartite motif containing 36
TWISTNB TWIST neighbor
UBTD1 ubiquitin domain containing 1
UNC119 unc-119 homolog (C. elegans)
UNC93B1 unc-93 homolog B1 (C. elegans)
USB1 U6 snRNA biogenesis 1
VLDLR very low density lipoprotein receptor
VPS9D1 VPS9 domain containing 1
WNT16 wingless-type MMTV integration site family, member 16
ZMAT5 zinc finger, matrin-type 5
ZNF286A zinc finger protein 286A
ZNF34 zinc finger protein 34
ZNF350 zinc finger protein 350
ZNF532 zinc finger protein 532