| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the sulfasalazine-5446 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ADARB1 | adenosine deaminase, RNA-specific, B1 |
| ALPPL2 | alkaline phosphatase, placental-like 2 |
| ANAPC13 | anaphase promoting complex subunit 13 |
| ANGPTL2 | angiopoietin-like 2 |
| ASIC2 | acid sensing (proton gated) ion channel 2 |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| BIN1 | bridging integrator 1 |
| CABP2 | calcium binding protein 2 |
| CALD1 | caldesmon 1 |
| CAMK2B | calcium/calmodulin-dependent protein kinase II beta |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CLCA2 | chloride channel accessory 2 |
| CLCN4 | chloride channel, voltage-sensitive 4 |
| CLEC4M | C-type lectin domain family 4, member M |
| COL5A1 | collagen, type V, alpha 1 |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) |
| CYP4F12 | cytochrome P450, family 4, subfamily F, polypeptide 12 |
| DCAF4 | DDB1 and CUL4 associated factor 4 |
| DDX51 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 |
| DIO2 | deiodinase, iodothyronine, type II |
| DPY19L1 | dpy-19-like 1 (C. elegans) |
| ETV6 | ets variant 6 |
| FAM182B | family with sequence similarity 182, member B |
| FMO5 | flavin containing monooxygenase 5 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GCKR | glucokinase (hexokinase 4) regulator |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GJA4 | gap junction protein, alpha 4, 37kDa |
| GM2A | GM2 ganglioside activator |
| GNPTAB | N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits |
| GPR157 | G protein-coupled receptor 157 |
| GPRC5D | G protein-coupled receptor, class C, group 5, member D |
| GRM4 | glutamate receptor, metabotropic 4 |
| HAAO | 3-hydroxyanthranilate 3,4-dioxygenase |
| HIPK3 | homeodomain interacting protein kinase 3 |
| HIST1H4H | histone cluster 1, H4h |
| HNMT | histamine N-methyltransferase |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IFI44 | interferon-induced protein 44 |
| IGHMBP2 | immunoglobulin mu binding protein 2 |
| JAG1 | jagged 1 |
| JAKMIP2 | janus kinase and microtubule interacting protein 2 |
| KCNJ4 | potassium channel, inwardly rectifying subfamily J, member 4 |
| KHSRP | KH-type splicing regulatory protein |
| KIAA0319L | KIAA0319-like |
| KLF12 | Kruppel-like factor 12 |
| LAIR1 | leukocyte-associated immunoglobulin-like receptor 1 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LOX | lysyl oxidase |
| LTBP4 | latent transforming growth factor beta binding protein 4 |
| MBD2 | methyl-CpG binding domain protein 2 |
| MON2 | MON2 homolog (S. cerevisiae) |
| MXRA8 | matrix-remodelling associated 8 |
| MYCNOS | MYCN opposite strand |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NCR3 | natural cytotoxicity triggering receptor 3 |
| NEFM | neurofilament, medium polypeptide |
| NGLY1 | N-glycanase 1 |
| NOX1 | NADPH oxidase 1 |
| NPY2R | neuropeptide Y receptor Y2 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| NRP1 | neuropilin 1 |
| OR2F2 | olfactory receptor, family 2, subfamily F, member 2 |
| PCDH1 | protocadherin 1 |
| PCDHB11 | protocadherin beta 11 |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PDGFB | platelet-derived growth factor beta polypeptide |
| PDZD2 | PDZ domain containing 2 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLSCR4 | phospholipid scramblase 4 |
| POM121L9P | POM121 transmembrane nucleoporin-like 9, pseudogene |
| PSAT1 | phosphoserine aminotransferase 1 |
| PTGDR2 | prostaglandin D2 receptor 2 |
| PTRF | polymerase I and transcript release factor |
| RAB40AL | RAB40A, member RAS oncogene family-like |
| REPS1 | RALBP1 associated Eps domain containing 1 |
| RIMS3 | regulating synaptic membrane exocytosis 3 |
| RORC | RAR-related orphan receptor C |
| S100A8 | S100 calcium binding protein A8 |
| SFTPD | surfactant protein D |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 |
| SLCO4C1 | solute carrier organic anion transporter family, member 4C1 |
| SNTA1 | syntrophin, alpha 1 |
| SPPL2B | signal peptide peptidase like 2B |
| SPRY4 | sprouty homolog 4 (Drosophila) |
| SSX3 | synovial sarcoma, X breakpoint 3 |
| STK11 | serine/threonine kinase 11 |
| TBX6 | T-box 6 |
| TFEB | transcription factor EB |
| TPP1 | tripeptidyl peptidase I |
| TTC39A | tetratricopeptide repeat domain 39A |
| ZBTB18 | zinc finger and BTB domain containing 18 |
| ZEB1 | zinc finger E-box binding homeobox 1 |
| Symbol | Name |
|---|---|
| ADCY7 | adenylate cyclase 7 |
| AFF4 | AF4/FMR2 family, member 4 |
| ARNTL2 | aryl hydrocarbon receptor nuclear translocator-like 2 |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| ATF3 | activating transcription factor 3 |
| ATP10D | ATPase, class V, type 10D |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| B9D2 | B9 protein domain 2 |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| CAPN5 | calpain 5 |
| CCNO | cyclin O |
| CD83 | CD83 molecule |
| CGA | glycoprotein hormones, alpha polypeptide |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CIDEC | cell death-inducing DFFA-like effector c |
| CLGN | calmegin |
| DBF4B | DBF4 zinc finger B |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| FAM212B | family with sequence similarity 212, member B |
| FBXO4 | F-box protein 4 |
| FILIP1L | filamin A interacting protein 1-like |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 |
| GPR143 | G protein-coupled receptor 143 |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H3G | histone cluster 1, H3g |
| HYI | hydroxypyruvate isomerase (putative) |
| IGFBP6 | insulin-like growth factor binding protein 6 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon |
| IQCG | IQ motif containing G |
| KLF2 | Kruppel-like factor 2 |
| KPNA5 | karyopherin alpha 5 (importin alpha 6) |
| LHX6 | LIM homeobox 6 |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MCC | mutated in colorectal cancers |
| MRPS18C | mitochondrial ribosomal protein S18C |
| NIPAL2 | NIPA-like domain containing 2 |
| OSMR | oncostatin M receptor |
| PAQR3 | progestin and adipoQ receptor family member III |
| PCDHA9 | protocadherin alpha 9 |
| PDE8B | phosphodiesterase 8B |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PSG4 | pregnancy specific beta-1-glycoprotein 4 |
| PTDSS2 | phosphatidylserine synthase 2 |
| RAB11FIP5 | RAB11 family interacting protein 5 (class I) |
| RCAN3 | RCAN family member 3 |
| RGS2 | regulator of G-protein signaling 2 |
| RIN2 | Ras and Rab interactor 2 |
| RNF39 | ring finger protein 39 |
| RPAP1 | RNA polymerase II associated protein 1 |
| RPGRIP1L | RPGRIP1-like |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 |
| SIRT6 | sirtuin 6 |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SP1 | Sp1 transcription factor |
| SPRYD7 | SPRY domain containing 7 |
| STK16 | serine/threonine kinase 16 |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
| TFPI2 | tissue factor pathway inhibitor 2 |
| TLN1 | talin 1 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| TSNAXIP1 | translin-associated factor X interacting protein 1 |
| TTBK2 | tau tubulin kinase 2 |
| UBXN6 | UBX domain protein 6 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 |
| UPP1 | uridine phosphorylase 1 |
| VASH2 | vasohibin 2 |
| VEGFC | vascular endothelial growth factor C |
| ZDHHC11 | zinc finger, DHHC-type containing 11 |
| ZFP37 | ZFP37 zinc finger protein |
| ZNF134 | zinc finger protein 134 |
| ZNF253 | zinc finger protein 253 |
| ZNF428 | zinc finger protein 428 |
| ZNF480 | zinc finger protein 480 |
| ZNF573 | zinc finger protein 573 |
| ZNF83 | zinc finger protein 83 |
| ZNF862 | zinc finger protein 862 |
