sulfathiazole-1463 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the sulfathiazole-1463 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ADRBK2 adrenergic, beta, receptor kinase 2
AKT3 v-akt murine thymoma viral oncogene homolog 3
ALPK1 alpha-kinase 1
ARHGAP33 Rho GTPase activating protein 33
ATAT1 alpha tubulin acetyltransferase 1
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide
C5AR2 complement component 5a receptor 2
C9ORF156 chromosome 9 open reading frame 156
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCL22 chemokine (C-C motif) ligand 22
CCR2 chemokine (C-C motif) receptor 2
CD48 CD48 molecule
CD58 CD58 molecule
CD82 CD82 molecule
CDC25C cell division cycle 25C
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CRTC1 CREB regulated transcription coactivator 1
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
CUL3 cullin 3
DCTN2 dynactin 2 (p50)
DDX52 DEAD (Asp-Glu-Ala-Asp) box polypeptide 52
DESI2 desumoylating isopeptidase 2
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DSPP dentin sialophosphoprotein
DSTYK dual serine/threonine and tyrosine protein kinase
EMID1 EMI domain containing 1
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
EPHX2 epoxide hydrolase 2, cytoplasmic
ERAP1 endoplasmic reticulum aminopeptidase 1
EXO5 exonuclease 5
F3 coagulation factor III (thromboplastin, tissue factor)
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FGF21 fibroblast growth factor 21
GHRHR growth hormone releasing hormone receptor
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GOSR2 golgi SNAP receptor complex member 2
GPATCH3 G patch domain containing 3
GRM1 glutamate receptor, metabotropic 1
GSPT1 G1 to S phase transition 1
HDAC11 histone deacetylase 11
HFE hemochromatosis
HIST1H1E histone cluster 1, H1e
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HPX hemopexin
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IL1RN interleukin 1 receptor antagonist
IRF9 interferon regulatory factor 9
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KLRD1 killer cell lectin-like receptor subfamily D, member 1
LRP6 low density lipoprotein receptor-related protein 6
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MAPKBP1 mitogen-activated protein kinase binding protein 1
MBD1 methyl-CpG binding domain protein 1
MBTD1 mbt domain containing 1
MEG3 maternally expressed 3 (non-protein coding)
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NGLY1 N-glycanase 1
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NTF3 neurotrophin 3
OASL 2'-5'-oligoadenylate synthetase-like
OMD osteomodulin
OVOL2 ovo-like zinc finger 2
PADI1 peptidyl arginine deiminase, type I
PGAP3 post-GPI attachment to proteins 3
PHLDB1 pleckstrin homology-like domain, family B, member 1
PRDM2 PR domain containing 2, with ZNF domain
RABEP2 rabaptin, RAB GTPase binding effector protein 2
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RELN reelin
RPL13P5 ribosomal protein L13 pseudogene 5
SCD5 stearoyl-CoA desaturase 5
SCRN3 secernin 3
SH3BP2 SH3-domain binding protein 2
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOX15 SRY (sex determining region Y)-box 15
SPDEF SAM pointed domain containing ETS transcription factor
SPTAN1 spectrin, alpha, non-erythrocytic 1
STRN striatin, calmodulin binding protein
TBX6 T-box 6
THNSL2 threonine synthase-like 2 (S. cerevisiae)
TMEM242 transmembrane protein 242
TMEM259 transmembrane protein 259
TMPRSS2 transmembrane protease, serine 2
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TPM3 tropomyosin 3
TRAK1 trafficking protein, kinesin binding 1
TRIL TLR4 interactor with leucine-rich repeats
TUBA3C tubulin, alpha 3c
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
ZCCHC4 zinc finger, CCHC domain containing 4
ZNF324 zinc finger protein 324

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ACAD10 acyl-CoA dehydrogenase family, member 10
ACTG2 actin, gamma 2, smooth muscle, enteric
AGO1 argonaute RISC catalytic component 1
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
BTBD7 BTB (POZ) domain containing 7
C19ORF73 chromosome 19 open reading frame 73
CAMKMT calmodulin-lysine N-methyltransferase
CBX4 chromobox homolog 4
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CHML choroideremia-like (Rab escort protein 2)
CNGB3 cyclic nucleotide gated channel beta 3
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CST6 cystatin E/M
CTC1 CTS telomere maintenance complex component 1
CUEDC1 CUE domain containing 1
CUL9 cullin 9
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DOCK1 dedicator of cytokinesis 1
DSCAM Down syndrome cell adhesion molecule
DUSP2 dual specificity phosphatase 2
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EFCAB2 EF-hand calcium binding domain 2
EGFL7 EGF-like-domain, multiple 7
ERN1 endoplasmic reticulum to nucleus signaling 1
FAM188A family with sequence similarity 188, member A
FBXL2 F-box and leucine-rich repeat protein 2
FSTL3 follistatin-like 3 (secreted glycoprotein)
FZD4 frizzled class receptor 4
GAMT guanidinoacetate N-methyltransferase
GLRX glutaredoxin (thioltransferase)
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HIST1H2AI histone cluster 1, H2ai
IL22 interleukin 22
INPP5J inositol polyphosphate-5-phosphatase J
KIAA0125 KIAA0125
KIZ kizuna centrosomal protein
KLF7 Kruppel-like factor 7 (ubiquitous)
KLHL26 kelch-like family member 26
LMBR1L limb development membrane protein 1-like
LMCD1 LIM and cysteine-rich domains 1
LOC257152 uncharacterized LOC257152
LZTR1 leucine-zipper-like transcription regulator 1
MAP6D1 MAP6 domain containing 1
MEFV Mediterranean fever
MFSD11 major facilitator superfamily domain containing 11
MYL5 myosin, light chain 5, regulatory
MYO1D myosin ID
NHEJ1 nonhomologous end-joining factor 1
NKX3-2 NK3 homeobox 2
NRGN neurogranin (protein kinase C substrate, RC3)
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
OSMR oncostatin M receptor
PAQR6 progestin and adipoQ receptor family member VI
PCOLCE2 procollagen C-endopeptidase enhancer 2
PEX26 peroxisomal biogenesis factor 26
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PIBF1 progesterone immunomodulatory binding factor 1
PISD phosphatidylserine decarboxylase
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PPP1R13B protein phosphatase 1, regulatory subunit 13B
PRR4 proline rich 4 (lacrimal)
PTK6 protein tyrosine kinase 6
RIN2 Ras and Rab interactor 2
RNF31 ring finger protein 31
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SIRT6 sirtuin 6
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SMCO4 single-pass membrane protein with coiled-coil domains 4
SND1-IT1 SND1 intronic transcript 1
SOX12 SRY (sex determining region Y)-box 12
SPAG4 sperm associated antigen 4
SPINK4 serine peptidase inhibitor, Kazal type 4
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TCTN1 tectonic family member 1
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TMEM180 transmembrane protein 180
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TRAPPC11 trafficking protein particle complex 11
TRMT1L tRNA methyltransferase 1 homolog (S. cerevisiae)-like
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TSPAN1 tetraspanin 1
TSPAN5 tetraspanin 5
UBQLN4 ubiquilin 4
USP36 ubiquitin specific peptidase 36
VWA1 von Willebrand factor A domain containing 1
ZBTB22 zinc finger and BTB domain containing 22
ZNF350 zinc finger protein 350
ZNF442 zinc finger protein 442
ZNF839 zinc finger protein 839
ZSCAN31 zinc finger and SCAN domain containing 31