sulfathiazole-1963 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the sulfathiazole-1963 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOT11 acyl-CoA thioesterase 11
ACTA2 actin, alpha 2, smooth muscle, aorta
ADAM30 ADAM metallopeptidase domain 30
AHCYL2 adenosylhomocysteinase-like 2
ANKRD12 ankyrin repeat domain 12
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
BICD1 bicaudal D homolog 1 (Drosophila)
CADM3 cell adhesion molecule 3
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CARTPT CART prepropeptide
CCDC64 coiled-coil domain containing 64
CCDC94 coiled-coil domain containing 94
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CD2BP2 CD2 (cytoplasmic tail) binding protein 2
CD320 CD320 molecule
CEL carboxyl ester lipase
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHD3 chromodomain helicase DNA binding protein 3
CIDEC cell death-inducing DFFA-like effector c
DBF4B DBF4 zinc finger B
DBP D site of albumin promoter (albumin D-box) binding protein
DEAF1 DEAF1 transcription factor
DERL2 derlin 2
DOK2 docking protein 2, 56kDa
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
ELOVL6 ELOVL fatty acid elongase 6
ENOSF1 enolase superfamily member 1
ENOX2 ecto-NOX disulfide-thiol exchanger 2
FAM53B family with sequence similarity 53, member B
FER1L4 fer-1-like family member 4, pseudogene (functional)
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11
GBP2 guanylate binding protein 2, interferon-inducible
GK glycerol kinase
GPR20 G protein-coupled receptor 20
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa
HFE hemochromatosis
HIST1H4J histone cluster 1, H4j
ICAM1 intercellular adhesion molecule 1
IFITM3 interferon induced transmembrane protein 3
IGHM immunoglobulin heavy constant mu
ITGB1BP1 integrin beta 1 binding protein 1
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIAA0355 KIAA0355
KIAA1109 KIAA1109
LETM1 leucine zipper-EF-hand containing transmembrane protein 1
MAGED2 melanoma antigen family D2
MAPK10 mitogen-activated protein kinase 10
MASP2 mannan-binding lectin serine peptidase 2
MAST2 microtubule associated serine/threonine kinase 2
MAST3 microtubule associated serine/threonine kinase 3
MFSD7 major facilitator superfamily domain containing 7
MICA MHC class I polypeptide-related sequence A
MID2 midline 2
MNS1 meiosis-specific nuclear structural 1
MRC2 mannose receptor, C type 2
MST1 macrophage stimulating 1
MZF1 myeloid zinc finger 1
NAAA N-acylethanolamine acid amidase
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NAP1L4 nucleosome assembly protein 1-like 4
NAPG N-ethylmaleimide-sensitive factor attachment protein, gamma
NBEAL2 neurobeachin-like 2
NCR2 natural cytotoxicity triggering receptor 2
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NR4A1 nuclear receptor subfamily 4, group A, member 1
PDCL phosducin-like
PDZD7 PDZ domain containing 7
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3
PLCD1 phospholipase C, delta 1
PPP1R7 protein phosphatase 1, regulatory subunit 7
PVR poliovirus receptor
RAD54L2 RAD54-like 2 (S. cerevisiae)
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
RGS1 regulator of G-protein signaling 1
RNASE3 ribonuclease, RNase A family, 3
RPE ribulose-5-phosphate-3-epimerase
SAG S-antigen; retina and pineal gland (arrestin)
SLC19A1 solute carrier family 19 (folate transporter), member 1
SRCAP Snf2-related CREBBP activator protein
SRSF11 serine/arginine-rich splicing factor 11
STX2 syntaxin 2
TERT telomerase reverse transcriptase
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TNK2 tyrosine kinase, non-receptor, 2
TPCN1 two pore segment channel 1
TRD T cell receptor delta locus
TRIP10 thyroid hormone receptor interactor 10
TYR tyrosinase
UBXN6 UBX domain protein 6
USF2 upstream transcription factor 2, c-fos interacting
YKT6 YKT6 v-SNARE homolog (S. cerevisiae)
ZNF224 zinc finger protein 224
ZNF783 zinc finger family member 783
ZSWIM1 zinc finger, SWIM-type containing 1

decreased expression

Symbol Name
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3
ABHD3 abhydrolase domain containing 3
ACOT9 acyl-CoA thioesterase 9
ACP2 acid phosphatase 2, lysosomal
AHR aryl hydrocarbon receptor
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1
ALG6 ALG6, alpha-1,3-glucosyltransferase
ANKRD40 ankyrin repeat domain 40
ANXA6 annexin A6
ARID5B AT rich interactive domain 5B (MRF1-like)
ATXN2 ataxin 2
B3GNT1
BCL7C B-cell CLL/lymphoma 7C
CALM2 calmodulin 2 (phosphorylase kinase, delta)
CAPNS1 calpain, small subunit 1
CCNA1 cyclin A1
CD302 CD302 molecule
CDC42SE1 CDC42 small effector 1
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CNR2 cannabinoid receptor 2 (macrophage)
COMMD8 COMM domain containing 8
CPOX coproporphyrinogen oxidase
CRY1 cryptochrome circadian clock 1
DENND4A DENN/MADD domain containing 4A
DTWD1 DTW domain containing 1
EI24 etoposide induced 2.4
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
EPS15 epidermal growth factor receptor pathway substrate 15
ERBB2IP erbb2 interacting protein
FCHSD2 FCH and double SH3 domains 2
GALT galactose-1-phosphate uridylyltransferase
GCLM glutamate-cysteine ligase, modifier subunit
GINS1 GINS complex subunit 1 (Psf1 homolog)
GMPR2 guanosine monophosphate reductase 2
GNG10 guanine nucleotide binding protein (G protein), gamma 10
GPATCH2 G patch domain containing 2
GSR glutathione reductase
GSTM3 glutathione S-transferase mu 3 (brain)
HIST1H1E histone cluster 1, H1e
IFNA17 interferon, alpha 17
INO80D INO80 complex subunit D
KCTD20 potassium channel tetramerization domain containing 20
KCTD9 potassium channel tetramerization domain containing 9
KLHL12 kelch-like family member 12
LAMP5 lysosomal-associated membrane protein family, member 5
LOC642236 FSHD region gene 1 pseudogene
LRRK1 leucine-rich repeat kinase 1
LSP1 lymphocyte-specific protein 1
LYRM2 LYR motif containing 2
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAGOHB mago-nashi homolog B (Drosophila)
MAPKBP1 mitogen-activated protein kinase binding protein 1
MCTP1 multiple C2 domains, transmembrane 1
MEST mesoderm specific transcript
MFF mitochondrial fission factor
MYO5C myosin VC
NT5DC3 5'-nucleotidase domain containing 3
NUCLEOLIN nucleolin multifunctional protein
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PAK1IP1 PAK1 interacting protein 1
PAQR4 progestin and adipoQ receptor family member IV
PIBF1 progesterone immunomodulatory binding factor 1
PIGK phosphatidylinositol glycan anchor biosynthesis, class K
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PRMT3 protein arginine methyltransferase 3
PWP2 PWP2 periodic tryptophan protein homolog (yeast)
RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6
RARS arginyl-tRNA synthetase
RPA2 replication protein A2, 32kDa
RPS10P5 ribosomal protein S10 pseudogene 5
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
RRAGA Ras-related GTP binding A
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SIRT7 sirtuin 7
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SNX10 sorting nexin 10
SNX15 sorting nexin 15
SP140L SP140 nuclear body protein-like
SRP19 signal recognition particle 19kDa
STAU2 staufen double-stranded RNA binding protein 2
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
THAP11 THAP domain containing 11
TIGAR TP53 induced glycolysis regulatory phosphatase
TMEM184C transmembrane protein 184C
TMEM53 transmembrane protein 53
TRAM2 translocation associated membrane protein 2
TRIM37 tripartite motif containing 37
TRMT11 tRNA methyltransferase 11 homolog (S. cerevisiae)
TSLIG2 tRNA splicing ligase complex subunit 2
TTC13 tetratricopeptide repeat domain 13
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
USP6 ubiquitin specific peptidase 6
VCPKMT valosin containing protein lysine (K) methyltransferase
WDR18 WD repeat domain 18
YIPF5 Yip1 domain family, member 5
ZNF432 zinc finger protein 432
ZNF85 zinc finger protein 85