sulfathiazole-4183 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the sulfathiazole-4183 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACHE acetylcholinesterase (Yt blood group)
ACVR1B activin A receptor, type IB
ADCK2 aarF domain containing kinase 2
AGFG2 ArfGAP with FG repeats 2
AK5 adenylate kinase 5
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
AP4S1 adaptor-related protein complex 4, sigma 1 subunit
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2
B3GAT1 beta-1,3-glucuronyltransferase 1
BBC3 BCL2 binding component 3
BLZF1 basic leucine zipper nuclear factor 1
BTG3 BTG family, member 3
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C17ORF70 chromosome 17 open reading frame 70
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CASP2 caspase 2, apoptosis-related cysteine peptidase
CD58 CD58 molecule
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CLEC4E C-type lectin domain family 4, member E
CORO2B coronin, actin binding protein, 2B
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DGCR8 DGCR8 microprocessor complex subunit
DIAPH2-AS1 DIAPH2 antisense RNA 1
DMRT1 doublesex and mab-3 related transcription factor 1
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
EFR3B EFR3 homolog B (S. cerevisiae)
EGFR epidermal growth factor receptor
EGR1 early growth response 1
EXD3 exonuclease 3'-5' domain containing 3
FBXO31 F-box protein 31
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FLT1 fms-related tyrosine kinase 1
FMO5 flavin containing monooxygenase 5
FMOD fibromodulin
GADD45G growth arrest and DNA-damage-inducible, gamma
GAL3ST4 galactose-3-O-sulfotransferase 4
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GSTM5 glutathione S-transferase mu 5
HDAC11 histone deacetylase 11
HIST1H2BL histone cluster 1, H2bl
HTR5A 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
ICA1 islet cell autoantigen 1, 69kDa
IFITM1 interferon induced transmembrane protein 1
IQCK IQ motif containing K
ITGB8 integrin, beta 8
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KCTD14 potassium channel tetramerization domain containing 14
KLRAP1 killer cell lectin-like receptor subfamily A pseudogene 1
LCK LCK proto-oncogene, Src family tyrosine kinase
LDB2 LIM domain binding 2
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAGEA5 melanoma antigen family A5
MAN1A2 mannosidase, alpha, class 1A, member 2
MMP19 matrix metallopeptidase 19
MR1 major histocompatibility complex, class I-related
MST1 macrophage stimulating 1
MTRF1L mitochondrial translational release factor 1-like
MYF5 myogenic factor 5
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
NFX1 nuclear transcription factor, X-box binding 1
PLG plasminogen
PNMAL1 paraneoplastic Ma antigen family-like 1
PPARD peroxisome proliferator-activated receptor delta
RAB36 RAB36, member RAS oncogene family
RGS12 regulator of G-protein signaling 12
RUNDC3A RUN domain containing 3A
SATB2 SATB homeobox 2
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SDS serine dehydratase
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SMAD4 SMAD family member 4
SMYD2 SET and MYND domain containing 2
TBC1D2B TBC1 domain family, member 2B
THSD4 thrombospondin, type I, domain containing 4
TMEM206 transmembrane protein 206
TSPY1 testis specific protein, Y-linked 1
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
VCL vinculin
WHSC1 Wolf-Hirschhorn syndrome candidate 1
WSB1 WD repeat and SOCS box containing 1
ZBED4 zinc finger, BED-type containing 4
ZC2HC1C zinc finger, C2HC-type containing 1C
ZMIZ2 zinc finger, MIZ-type containing 2
ZMYM5 zinc finger, MYM-type 5
ZNF573 zinc finger protein 573
ZNF639 zinc finger protein 639
ZNF688 zinc finger protein 688
ZSCAN32 zinc finger and SCAN domain containing 32
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACE angiotensin I converting enzyme
ADAM2 ADAM metallopeptidase domain 2
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ALPK1 alpha-kinase 1
ALS2CL ALS2 C-terminal like
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ANXA2P1 annexin A2 pseudogene 1
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARRB2 arrestin, beta 2
BSPRY B-box and SPRY domain containing
BTF3P12 basic transcription factor 3 pseudogene 12
C14ORF105 chromosome 14 open reading frame 105
C5ORF45 chromosome 5 open reading frame 45
C7ORF69 chromosome 7 open reading frame 69
C8A complement component 8, alpha polypeptide
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CASP5 caspase 5, apoptosis-related cysteine peptidase
CASS4 Cas scaffolding protein family member 4
CBX8 chromobox homolog 8
CLDN1 claudin 1
CLTCL1 clathrin, heavy chain-like 1
CRYGC crystallin, gamma C
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
EBF2 early B-cell factor 2
ERN2 endoplasmic reticulum to nucleus signaling 2
EVPL envoplakin
FAM53B family with sequence similarity 53, member B
FBXL6 F-box and leucine-rich repeat protein 6
FRMPD1 FERM and PDZ domain containing 1
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
GSDMD gasdermin D
GSTA3 glutathione S-transferase alpha 3
HIST1H2AK histone cluster 1, H2ak
HIST1H2BJ histone cluster 1, H2bj
HIST1H2BN histone cluster 1, H2bn
HIST1H4E histone cluster 1, H4e
HOXA6 homeobox A6
HOXB9 homeobox B9
HOXC8 homeobox C8
ICOS inducible T-cell co-stimulator
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
ITGB7 integrin, beta 7
KANSL3 KAT8 regulatory NSL complex subunit 3
KLF13 Kruppel-like factor 13
KRT20 keratin 20, type I
KRT86 keratin 86, type II
LIME1 Lck interacting transmembrane adaptor 1
MAGEF1 melanoma antigen family F1
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MFGE8 milk fat globule-EGF factor 8 protein
MGP matrix Gla protein
MTCP1 mature T-cell proliferation 1
MUM1 melanoma associated antigen (mutated) 1
MYH15 myosin, heavy chain 15
MYL9 myosin, light chain 9, regulatory
MYO1F myosin IF
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
ORAI3 ORAI calcium release-activated calcium modulator 3
OSBP2 oxysterol binding protein 2
OSMR oncostatin M receptor
PAIP2B poly(A) binding protein interacting protein 2B
PCDH12 protocadherin 12
PLBD1 phospholipase B domain containing 1
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PLTP phospholipid transfer protein
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RIBC2 RIB43A domain with coiled-coils 2
RUNX1-IT1 RUNX1 intronic transcript 1
S1PR1 sphingosine-1-phosphate receptor 1
SCIN scinderin
SCUBE3 signal peptide, CUB domain, EGF-like 3
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SNRPN small nuclear ribonucleoprotein polypeptide N
SOX21 SRY (sex determining region Y)-box 21
SPATA1 spermatogenesis associated 1
SPTBN2 spectrin, beta, non-erythrocytic 2
SSBP3 single stranded DNA binding protein 3
STEAP4 STEAP family member 4
TEAD3 TEA domain family member 3
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TIMP4 TIMP metallopeptidase inhibitor 4
TNRC6B trinucleotide repeat containing 6B
TSPAN2 tetraspanin 2
TTLL1 tubulin tyrosine ligase-like family member 1
UGT8 UDP glycosyltransferase 8
ULK1 unc-51 like autophagy activating kinase 1
VGF VGF nerve growth factor inducible
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZNF222 zinc finger protein 222
ZNF428 zinc finger protein 428
ZNF528 zinc finger protein 528