| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the sulfinpyrazone-1574 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACAA2 | acetyl-CoA acyltransferase 2 |
| ACAN | aggrecan |
| ACIN1 | apoptotic chromatin condensation inducer 1 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta |
| ACTR3B | ARP3 actin-related protein 3 homolog B (yeast) |
| ADM2 | adrenomedullin 2 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 |
| ANKRD46 | ankyrin repeat domain 46 |
| APOBEC3C | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C |
| ARNTL | aryl hydrocarbon receptor nuclear translocator-like |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
| C5ORF30 | chromosome 5 open reading frame 30 |
| CANT1 | calcium activated nucleotidase 1 |
| CCDC94 | coiled-coil domain containing 94 |
| CCNL2 | cyclin L2 |
| CD300A | CD300a molecule |
| CHEK1 | checkpoint kinase 1 |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| COPS8 | COP9 signalosome subunit 8 |
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) |
| CTNS | cystinosin, lysosomal cystine transporter |
| CTRC | chymotrypsin C (caldecrin) |
| DEAF1 | DEAF1 transcription factor |
| ELK1 | ELK1, member of ETS oncogene family |
| EXOC7 | exocyst complex component 7 |
| FAM105A | family with sequence similarity 105, member A |
| FASTK | Fas-activated serine/threonine kinase |
| FBXL4 | F-box and leucine-rich repeat protein 4 |
| FGFR1 | fibroblast growth factor receptor 1 |
| GALNS | galactosamine (N-acetyl)-6-sulfatase |
| GLRX3 | glutaredoxin 3 |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GNB5 | guanine nucleotide binding protein (G protein), beta 5 |
| GPR137 | G protein-coupled receptor 137 |
| GRIP2 | glutamate receptor interacting protein 2 |
| GTF3C2 | general transcription factor IIIC, polypeptide 2, beta 110kDa |
| HFE | hemochromatosis |
| HOOK2 | hook microtubule-tethering protein 2 |
| HOXA10 | homeobox A10 |
| HSPB11 | heat shock protein family B (small), member 11 |
| HTT | huntingtin |
| IL1RAP | interleukin 1 receptor accessory protein |
| IL27RA | interleukin 27 receptor, alpha |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) |
| KDM5A | lysine (K)-specific demethylase 5A |
| KPNB1 | karyopherin (importin) beta 1 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LONRF3 | LON peptidase N-terminal domain and ring finger 3 |
| LPCAT3 | lysophosphatidylcholine acyltransferase 3 |
| MBD1 | methyl-CpG binding domain protein 1 |
| MKL1 | megakaryoblastic leukemia (translocation) 1 |
| MLXIP | MLX interacting protein |
| MOSPD3 | motile sperm domain containing 3 |
| MPDU1 | mannose-P-dolichol utilization defect 1 |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MYO1C | myosin IC |
| MZF1 | myeloid zinc finger 1 |
| NDRG2 | NDRG family member 2 |
| NHEJ1 | nonhomologous end-joining factor 1 |
| NKTR | natural killer cell triggering receptor |
| NRIP1 | nuclear receptor interacting protein 1 |
| NUDT1 | nudix (nucleoside diphosphate linked moiety X)-type motif 1 |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta |
| POP1 | processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) |
| PRRC1 | proline-rich coiled-coil 1 |
| PTK2 | protein tyrosine kinase 2 |
| RAD17 | RAD17 homolog (S. pombe) |
| REC8 | REC8 meiotic recombination protein |
| RECQL4 | RecQ protein-like 4 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| RNF141 | ring finger protein 141 |
| RPL10 | ribosomal protein L10 |
| SCD5 | stearoyl-CoA desaturase 5 |
| SEMA4F | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F |
| SIGLEC7 | sialic acid binding Ig-like lectin 7 |
| SIRT6 | sirtuin 6 |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SPG20 | spastic paraplegia 20 (Troyer syndrome) |
| TFPT | TCF3 (E2A) fusion partner (in childhood Leukemia) |
| THY1 | Thy-1 cell surface antigen |
| TMEM40 | transmembrane protein 40 |
| TRA | T cell receptor alpha locus |
| USB1 | U6 snRNA biogenesis 1 |
| USP2 | ubiquitin specific peptidase 2 |
| USP20 | ubiquitin specific peptidase 20 |
| USP34 | ubiquitin specific peptidase 34 |
| WWOX | WW domain containing oxidoreductase |
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 |
| ZIM2 | zinc finger, imprinted 2 |
| ZNF280D | zinc finger protein 280D |
| ZNF408 | zinc finger protein 408 |
| ZNF783 | zinc finger family member 783 |
| ZSWIM1 | zinc finger, SWIM-type containing 1 |
| Symbol | Name |
|---|---|
| AACS | acetoacetyl-CoA synthetase |
| ABCA11P | ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 |
| ANAPC2 | anaphase promoting complex subunit 2 |
| ASB13 | ankyrin repeat and SOCS box containing 13 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| BCOR | BCL6 corepressor |
| C11ORF68 | chromosome 11 open reading frame 68 |
| CCDC176 | coiled-coil domain containing 176 |
| CD82 | CD82 molecule |
| CDC25B | cell division cycle 25B |
| CDR2 | cerebellar degeneration-related protein 2, 62kDa |
| CEND1 | cell cycle exit and neuronal differentiation 1 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 |
| CHUK | conserved helix-loop-helix ubiquitous kinase |
| CLTCL1 | clathrin, heavy chain-like 1 |
| CNP | 2',3'-cyclic nucleotide 3' phosphodiesterase |
| CRNKL1 | crooked neck pre-mRNA splicing factor 1 |
| CTAGE9 | CTAGE family, member 9 |
| CTSH | cathepsin H |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DHDDS | dehydrodolichyl diphosphate synthase |
| DMXL1 | Dmx-like 1 |
| DPF2 | D4, zinc and double PHD fingers family 2 |
| EGR3 | early growth response 3 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 |
| EXOSC7 | exosome component 7 |
| FAM192A | family with sequence similarity 192, member A |
| FAM222B | family with sequence similarity 222, member B |
| FAM50B | family with sequence similarity 50, member B |
| GAB2 | GRB2-associated binding protein 2 |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GTF2F2 | general transcription factor IIF, polypeptide 2, 30kDa |
| GTF3C4 | general transcription factor IIIC, polypeptide 4, 90kDa |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HRSP12 | heat-responsive protein 12 |
| HSPBP1 | HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 |
| IFT88 | intraflagellar transport 88 |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 |
| LMBR1L | limb development membrane protein 1-like |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MBIP | MAP3K12 binding inhibitory protein 1 |
| MED24 | mediator complex subunit 24 |
| MSL2 | male-specific lethal 2 homolog (Drosophila) |
| MTERF1 | mitochondrial transcription termination factor 1 |
| NEDD8 | neural precursor cell expressed, developmentally down-regulated 8 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NIP7 | NIP7, nucleolar pre-rRNA processing protein |
| NOTCH1 | notch 1 |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 |
| OGFRL1 | opioid growth factor receptor-like 1 |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) |
| PAK1IP1 | PAK1 interacting protein 1 |
| PCNXL4 | pecanex-like 4 (Drosophila) |
| PCOLCE2 | procollagen C-endopeptidase enhancer 2 |
| PIP4K2C | phosphatidylinositol-5-phosphate 4-kinase, type II, gamma |
| RAB11FIP5 | RAB11 family interacting protein 5 (class I) |
| RAB1B | RAB1B, member RAS oncogene family |
| RAB5B | RAB5B, member RAS oncogene family |
| RABGGTA | Rab geranylgeranyltransferase, alpha subunit |
| RBM7 | RNA binding motif protein 7 |
| REEP4 | receptor accessory protein 4 |
| RIC8A | RIC8 guanine nucleotide exchange factor A |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 |
| RRAGA | Ras-related GTP binding A |
| SLC50A1 | solute carrier family 50 (sugar efflux transporter), member 1 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SLPI | secretory leukocyte peptidase inhibitor |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) |
| SRBD1 | S1 RNA binding domain 1 |
| SSSCA1 | Sjogren syndrome/scleroderma autoantigen 1 |
| STK39 | serine threonine kinase 39 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) |
| SUSD6 | sushi domain containing 6 |
| SYT13 | synaptotagmin XIII |
| TAC3 | tachykinin 3 |
| THBS4 | thrombospondin 4 |
| TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase |
| TRIM45 | tripartite motif containing 45 |
| TRIM66 | tripartite motif containing 66 |
| TUBA3C | tubulin, alpha 3c |
| TVP23B | trans-golgi network vesicle protein 23 homolog B (S. cerevisiae) |
| UBIAD1 | UbiA prenyltransferase domain containing 1 |
| UBQLN2 | ubiquilin 2 |
| UBQLN4 | ubiquilin 4 |
| UFSP2 | UFM1-specific peptidase 2 |
| WRN | Werner syndrome, RecQ helicase-like |
| ZCCHC10 | zinc finger, CCHC domain containing 10 |
| ZNF197 | zinc finger protein 197 |
| ZNF212 | zinc finger protein 212 |
| ZNF611 | zinc finger protein 611 |
| ZNF629 | zinc finger protein 629 |
| ZNF669 | zinc finger protein 669 |
