sulfinpyrazone-3192 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the sulfinpyrazone-3192 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOT11 acyl-CoA thioesterase 11
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADRA1A adrenoceptor alpha 1A
AGER advanced glycosylation end product-specific receptor
AKAP8L A kinase (PRKA) anchor protein 8-like
ALDOB aldolase B, fructose-bisphosphate
ALK anaplastic lymphoma receptor tyrosine kinase
AOAH acyloxyacyl hydrolase (neutrophil)
ARMC4 armadillo repeat containing 4
ATP2A3 ATPase, Ca++ transporting, ubiquitous
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3
BBS9 Bardet-Biedl syndrome 9
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BHMT betaine--homocysteine S-methyltransferase
BLVRA biliverdin reductase A
CA9 carbonic anhydrase IX
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCL13 chemokine (C-C motif) ligand 13
CCRL2 chemokine (C-C motif) receptor-like 2
CD1A CD1a molecule
CD22 CD22 molecule
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CPN2 carboxypeptidase N, polypeptide 2
DMPK dystrophia myotonica-protein kinase
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
EFCAB11 EF-hand calcium binding domain 11
ELSPBP1 epididymal sperm binding protein 1
ESR2 estrogen receptor 2 (ER beta)
FAM212B family with sequence similarity 212, member B
FGF1 fibroblast growth factor 1 (acidic)
FH fumarate hydratase
FKBP10 FK506 binding protein 10, 65 kDa
GLRX glutaredoxin (thioltransferase)
GLS glutaminase
GM2A GM2 ganglioside activator
GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble)
GPNMB glycoprotein (transmembrane) nmb
GRM4 glutamate receptor, metabotropic 4
HABP4 hyaluronan binding protein 4
HAND2-AS1 HAND2 antisense RNA 1 (head to head)
HDAC4 histone deacetylase 4
HLA-DOB major histocompatibility complex, class II, DO beta
HRASLS2 HRAS-like suppressor 2
HS6ST1 heparan sulfate 6-O-sulfotransferase 1
IAPP islet amyloid polypeptide
IL1B interleukin 1, beta
IRF4 interferon regulatory factor 4
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
KMT2A lysine (K)-specific methyltransferase 2A
LEFTY2 left-right determination factor 2
LRRC37A4P leucine rich repeat containing 37, member A4, pseudogene
MINK1 misshapen-like kinase 1
MLXIPL MLX interacting protein-like
MYH11 myosin, heavy chain 11, smooth muscle
NBR2 neighbor of BRCA1 gene 2 (non-protein coding)
OSGIN1 oxidative stress induced growth inhibitor 1
OTOR otoraplin
PAX8 paired box 8
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
RAB3B RAB3B, member RAS oncogene family
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RERGL RERG/RAS-like
RGS5 regulator of G-protein signaling 5
RPGRIP1L RPGRIP1-like
RPH3A rabphilin 3A
RPL35A ribosomal protein L35a
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RUNX1 runt-related transcription factor 1
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SETD1A SET domain containing 1A
SFTPA2 surfactant protein A2
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC26A10 solute carrier family 26, member 10
SMIM14 small integral membrane protein 14
SPTA1 spectrin, alpha, erythrocytic 1
SSBP1 single-stranded DNA binding protein 1, mitochondrial
TAOK2 TAO kinase 2
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TBC1D29 TBC1 domain family, member 29
TGFBR3 transforming growth factor, beta receptor III
THRA thyroid hormone receptor, alpha
TIMP3 TIMP metallopeptidase inhibitor 3
TMEM242 transmembrane protein 242
TMEM63A transmembrane protein 63A
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
TSPAN12 tetraspanin 12
TWISTNB TWIST neighbor
UBE2B ubiquitin-conjugating enzyme E2B
UHRF1BP1L UHRF1 binding protein 1-like
USP29 ubiquitin specific peptidase 29
VGLL3 vestigial-like family member 3
WAPAL wings apart-like homolog (Drosophila)
WDR55 WD repeat domain 55
WSB1 WD repeat and SOCS box containing 1
ZNF155 zinc finger protein 155
ZNF419 zinc finger protein 419

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ACTG2 actin, gamma 2, smooth muscle, enteric
ADGRG2 adhesion G protein-coupled receptor G2
ADM adrenomedullin
ALS2CL ALS2 C-terminal like
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARL15 ADP-ribosylation factor-like 15
ARRB1 arrestin, beta 1
ASB7 ankyrin repeat and SOCS box containing 7
C16ORF45 chromosome 16 open reading frame 45
C17ORF80 chromosome 17 open reading frame 80
C22ORF29 chromosome 22 open reading frame 29
C2ORF27A chromosome 2 open reading frame 27A
CA11 carbonic anhydrase XI
CCDC85C coiled-coil domain containing 85C
CCP110 centriolar coiled coil protein 110kDa
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CDKN2AIP CDKN2A interacting protein
CHKB choline kinase beta
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CIR1 corepressor interacting with RBPJ, 1
CRLF1 cytokine receptor-like factor 1
CRY2 cryptochrome circadian clock 2
CRYBG3 beta-gamma crystallin domain containing 3
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DUSP5 dual specificity phosphatase 5
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
DYSF dysferlin
ELAVL3 ELAV like neuron-specific RNA binding protein 3
ELP6 elongator acetyltransferase complex subunit 6
FAM169A family with sequence similarity 169, member A
FAM186A family with sequence similarity 186, member A
FBXO31 F-box protein 31
FGF4 fibroblast growth factor 4
FGL1 fibrinogen-like 1
FLJ22184
GEMIN8 gem (nuclear organelle) associated protein 8
GID4 GID complex subunit 4
GMPR guanosine monophosphate reductase
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPX1 glutathione peroxidase 1
GRB7 growth factor receptor-bound protein 7
H2AFY2 H2A histone family, member Y2
HIST1H2BC histone cluster 1, H2bc
HIST1H2BJ histone cluster 1, H2bj
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOXC10 homeobox C10
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IFT140 intraflagellar transport 140
IFT54 intraflagellar transport 54
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IL17RA interleukin 17 receptor A
IL4R interleukin 4 receptor
IRF9 interferon regulatory factor 9
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIAA0754 KIAA0754
KIAA1456 KIAA1456
KIF13A kinesin family member 13A
LDHB lactate dehydrogenase B
LIN7A lin-7 homolog A (C. elegans)
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LMO2 LIM domain only 2 (rhombotin-like 1)
LYZ lysozyme
MAN2C1 mannosidase, alpha, class 2C, member 1
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MOCS3 molybdenum cofactor synthesis 3
MPO myeloperoxidase
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MSI1 musashi RNA-binding protein 1
MTA2 metastasis associated 1 family, member 2
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
ONECUT2 one cut homeobox 2
PACS1 phosphofurin acidic cluster sorting protein 1
PAQR6 progestin and adipoQ receptor family member VI
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLEKHO2 pleckstrin homology domain containing, family O member 2
POLH polymerase (DNA directed), eta
RAD54L2 RAD54-like 2 (S. cerevisiae)
RFTN1 raftlin, lipid raft linker 1
RPUSD2 RNA pseudouridylate synthase domain containing 2
SLC44A1 solute carrier family 44 (choline transporter), member 1
SRGN serglycin
ST5 suppression of tumorigenicity 5
TRPV6 transient receptor potential cation channel, subfamily V, member 6
UBXN6 UBX domain protein 6
USB1 U6 snRNA biogenesis 1
WDR19 WD repeat domain 19
WNT10B wingless-type MMTV integration site family, member 10B
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZBTB44 zinc finger and BTB domain containing 44
ZNF134 zinc finger protein 134
ZNF770 zinc finger protein 770