sulindac-168 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the sulindac-168 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABLIM3 actin binding LIM protein family, member 3
ACSL6 acyl-CoA synthetase long-chain family member 6
ADM2 adrenomedullin 2
ANO10 anoctamin 10
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
AQP3 aquaporin 3 (Gill blood group)
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
ARR3 arrestin 3, retinal (X-arrestin)
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
AVL9 AVL9 homolog (S. cerevisiase)
BICD1 bicaudal D homolog 1 (Drosophila)
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C2CD2L C2CD2-like
C5ORF30 chromosome 5 open reading frame 30
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CADM3 cell adhesion molecule 3
CBX8 chromobox homolog 8
CD2 CD2 molecule
CEP57 centrosomal protein 57kDa
CES3 carboxylesterase 3
CFAP74 cilia and flagella associated protein 74
CHN2 chimerin 2
CLEC11A C-type lectin domain family 11, member A
CTAGE5 CTAGE family, member 5
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
EPB41L2 erythrocyte membrane protein band 4.1-like 2
EXOC7 exocyst complex component 7
FBLN1 fibulin 1
FLJ10038 uncharacterized protein FLJ10038
FUZ fuzzy planar cell polarity protein
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GML glycosylphosphatidylinositol anchored molecule like
GRM8 glutamate receptor, metabotropic 8
HBB hemoglobin, beta
HIST1H2BD histone cluster 1, H2bd
HOXA5 homeobox A5
HS6ST1 heparan sulfate 6-O-sulfotransferase 1
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
INSIG1 insulin induced gene 1
JUN jun proto-oncogene
KIAA0141 KIAA0141
KRT2 keratin 2, type II
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LARP7 La ribonucleoprotein domain family, member 7
LENEP lens epithelial protein
LMF2 lipase maturation factor 2
MBD1 methyl-CpG binding domain protein 1
MED13L mediator complex subunit 13-like
MLXIPL MLX interacting protein-like
MMP19 matrix metallopeptidase 19
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MTF2 metal response element binding transcription factor 2
MTMR3 myotubularin related protein 3
MYOZ1 myozenin 1
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NEBL nebulette
NEU3 sialidase 3 (membrane sialidase)
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NMRK2 nicotinamide riboside kinase 2
NOC4L nucleolar complex associated 4 homolog (S. cerevisiae)
OPTN optineurin
PAWR PRKC, apoptosis, WT1, regulator
PAX8 paired box 8
PCYT1B phosphate cytidylyltransferase 1, choline, beta
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta
PDE8B phosphodiesterase 8B
PDK3 pyruvate dehydrogenase kinase, isozyme 3
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PISD phosphatidylserine decarboxylase
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PMP22 peripheral myelin protein 22
POM121 POM121 transmembrane nucleoporin
PPP1R10 protein phosphatase 1, regulatory subunit 10
RAD17 RAD17 homolog (S. pombe)
RAD51D RAD51 paralog D
RNFT1 ring finger protein, transmembrane 1
SASH1 SAM and SH3 domain containing 1
SCD5 stearoyl-CoA desaturase 5
SCYL3 SCY1-like 3 (S. cerevisiae)
SFTPB surfactant protein B
SIRT2 sirtuin 2
SIRT3 sirtuin 3
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SMIM8 small integral membrane protein 8
STARD13 StAR-related lipid transfer (START) domain containing 13
SYF2 SYF2 pre-mRNA-splicing factor
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TBRG4 transforming growth factor beta regulator 4
TEAD4 TEA domain family member 4
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast)
TJP3 tight junction protein 3
TTLL4 tubulin tyrosine ligase-like family member 4
UNC93B1 unc-93 homolog B1 (C. elegans)
WDR19 WD repeat domain 19
ZC2HC1A zinc finger, C2HC-type containing 1A
ZNF473 zinc finger protein 473
ZNF839 zinc finger protein 839

decreased expression

Symbol Name
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
ADIRF adipogenesis regulatory factor
ALPK1 alpha-kinase 1
AMN amnion associated transmembrane protein
AQP8 aquaporin 8
ASCC1 activating signal cointegrator 1 complex subunit 1
ATAD5 ATPase family, AAA domain containing 5
BAHCC1 BAH domain and coiled-coil containing 1
CCDC85C coiled-coil domain containing 85C
CCS copper chaperone for superoxide dismutase
CD79A CD79a molecule, immunoglobulin-associated alpha
CD82 CD82 molecule
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon
CENPO centromere protein O
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CPNE7 copine VII
CXORF56 chromosome X open reading frame 56
DDB2 damage-specific DNA binding protein 2, 48kDa
DLK2 delta-like 2 homolog (Drosophila)
DUSP13 dual specificity phosphatase 13
ELMO3 engulfment and cell motility 3
FAM153A family with sequence similarity 153, member A
FAM198B family with sequence similarity 198, member B
FAM76A family with sequence similarity 76, member A
FGD1 FYVE, RhoGEF and PH domain containing 1
FLJ11710 uncharacterized protein FLJ11710
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FYCO1 FYVE and coiled-coil domain containing 1
GAST gastrin
GJA9 gap junction protein, alpha 9, 59kDa
GLMN glomulin, FKBP associated protein
GPR35 G protein-coupled receptor 35
GRIP2 glutamate receptor interacting protein 2
GTF2I general transcription factor IIi
HDAC5 histone deacetylase 5
HDAC7 histone deacetylase 7
HELLS helicase, lymphoid-specific
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOXC11 homeobox C11
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IL2RG interleukin 2 receptor, gamma
KCNMB2 potassium channel subfamily M regulatory beta subunit 2
KDM7A lysine (K)-specific demethylase 7A
L2HGDH L-2-hydroxyglutarate dehydrogenase
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
LIMS2 LIM and senescent cell antigen-like domains 2
LINC00312 long intergenic non-protein coding RNA 312
LRP3 low density lipoprotein receptor-related protein 3
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LY6G6C lymphocyte antigen 6 complex, locus G6C
MAPK12 mitogen-activated protein kinase 12
MAS1 MAS1 proto-oncogene, G protein-coupled receptor
MNT MAX network transcriptional repressor
MPPED1 metallophosphoesterase domain containing 1
MSX1 msh homeobox 1
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MVP major vault protein
OMG oligodendrocyte myelin glycoprotein
PAK1IP1 PAK1 interacting protein 1
PCDHGA1 protocadherin gamma subfamily A, 1
PEMT phosphatidylethanolamine N-methyltransferase
PHC1 polyhomeotic homolog 1 (Drosophila)
PIGR polymeric immunoglobulin receptor
PKD2L1 polycystic kidney disease 2-like 1
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma
PRMT3 protein arginine methyltransferase 3
PRODH2 proline dehydrogenase (oxidase) 2
PROP1 PROP paired-like homeobox 1
QTRTD1 queuine tRNA-ribosyltransferase domain containing 1
RAB4B RAB4B, member RAS oncogene family
RBM47 RNA binding motif protein 47
RBMS3 RNA binding motif, single stranded interacting protein 3
REM1 RAS (RAD and GEM)-like GTP-binding 1
RLBP1 retinaldehyde binding protein 1
RRP1 ribosomal RNA processing 1
S100P S100 calcium binding protein P
SGK2 serum/glucocorticoid regulated kinase 2
SH2B3 SH2B adaptor protein 3
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
STARD3 StAR-related lipid transfer (START) domain containing 3
STX1A syntaxin 1A (brain)
T T, brachyury homolog (mouse)
TGFBI transforming growth factor, beta-induced, 68kDa
TMEM2 transmembrane protein 2
TSNAX translin-associated factor X
TUBA4B tubulin, alpha 4b
UBE2L6 ubiquitin-conjugating enzyme E2L 6
WASF1 WAS protein family, member 1
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
YAF2 YY1 associated factor 2
ZFHX2 zinc finger homeobox 2