| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the sulindac-168 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABLIM3 | actin binding LIM protein family, member 3 |
| ACSL6 | acyl-CoA synthetase long-chain family member 6 |
| ADM2 | adrenomedullin 2 |
| ANO10 | anoctamin 10 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| AQP3 | aquaporin 3 (Gill blood group) |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 |
| ARR3 | arrestin 3, retinal (X-arrestin) |
| ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
| AVL9 | AVL9 homolog (S. cerevisiase) |
| BICD1 | bicaudal D homolog 1 (Drosophila) |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| C2CD2L | C2CD2-like |
| C5ORF30 | chromosome 5 open reading frame 30 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CADM3 | cell adhesion molecule 3 |
| CBX8 | chromobox homolog 8 |
| CD2 | CD2 molecule |
| CEP57 | centrosomal protein 57kDa |
| CES3 | carboxylesterase 3 |
| CFAP74 | cilia and flagella associated protein 74 |
| CHN2 | chimerin 2 |
| CLEC11A | C-type lectin domain family 11, member A |
| CTAGE5 | CTAGE family, member 5 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DYRK4 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 |
| EXOC7 | exocyst complex component 7 |
| FBLN1 | fibulin 1 |
| FLJ10038 | uncharacterized protein FLJ10038 |
| FUZ | fuzzy planar cell polarity protein |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GML | glycosylphosphatidylinositol anchored molecule like |
| GRM8 | glutamate receptor, metabotropic 8 |
| HBB | hemoglobin, beta |
| HIST1H2BD | histone cluster 1, H2bd |
| HOXA5 | homeobox A5 |
| HS6ST1 | heparan sulfate 6-O-sulfotransferase 1 |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| INSIG1 | insulin induced gene 1 |
| JUN | jun proto-oncogene |
| KIAA0141 | KIAA0141 |
| KRT2 | keratin 2, type II |
| L3MBTL1 | l(3)mbt-like 1 (Drosophila) |
| LARP7 | La ribonucleoprotein domain family, member 7 |
| LENEP | lens epithelial protein |
| LMF2 | lipase maturation factor 2 |
| MBD1 | methyl-CpG binding domain protein 1 |
| MED13L | mediator complex subunit 13-like |
| MLXIPL | MLX interacting protein-like |
| MMP19 | matrix metallopeptidase 19 |
| MRE11A | MRE11 meiotic recombination 11 homolog A (S. cerevisiae) |
| MTF2 | metal response element binding transcription factor 2 |
| MTMR3 | myotubularin related protein 3 |
| MYOZ1 | myozenin 1 |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| NEBL | nebulette |
| NEU3 | sialidase 3 (membrane sialidase) |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NMRK2 | nicotinamide riboside kinase 2 |
| NOC4L | nucleolar complex associated 4 homolog (S. cerevisiae) |
| OPTN | optineurin |
| PAWR | PRKC, apoptosis, WT1, regulator |
| PAX8 | paired box 8 |
| PCYT1B | phosphate cytidylyltransferase 1, choline, beta |
| PDE6D | phosphodiesterase 6D, cGMP-specific, rod, delta |
| PDE8B | phosphodiesterase 8B |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 |
| PHLPP2 | PH domain and leucine rich repeat protein phosphatase 2 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PISD | phosphatidylserine decarboxylase |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 |
| PMP22 | peripheral myelin protein 22 |
| POM121 | POM121 transmembrane nucleoporin |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 |
| RAD17 | RAD17 homolog (S. pombe) |
| RAD51D | RAD51 paralog D |
| RNFT1 | ring finger protein, transmembrane 1 |
| SASH1 | SAM and SH3 domain containing 1 |
| SCD5 | stearoyl-CoA desaturase 5 |
| SCYL3 | SCY1-like 3 (S. cerevisiae) |
| SFTPB | surfactant protein B |
| SIRT2 | sirtuin 2 |
| SIRT3 | sirtuin 3 |
| SLC16A2 | solute carrier family 16, member 2 (thyroid hormone transporter) |
| SLC17A7 | solute carrier family 17 (vesicular glutamate transporter), member 7 |
| SMIM8 | small integral membrane protein 8 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 |
| SYF2 | SYF2 pre-mRNA-splicing factor |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
| TBRG4 | transforming growth factor beta regulator 4 |
| TEAD4 | TEA domain family member 4 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) |
| TJP3 | tight junction protein 3 |
| TTLL4 | tubulin tyrosine ligase-like family member 4 |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| WDR19 | WD repeat domain 19 |
| ZC2HC1A | zinc finger, C2HC-type containing 1A |
| ZNF473 | zinc finger protein 473 |
| ZNF839 | zinc finger protein 839 |
| Symbol | Name |
|---|---|
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 |
| ADIRF | adipogenesis regulatory factor |
| ALPK1 | alpha-kinase 1 |
| AMN | amnion associated transmembrane protein |
| AQP8 | aquaporin 8 |
| ASCC1 | activating signal cointegrator 1 complex subunit 1 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| CCDC85C | coiled-coil domain containing 85C |
| CCS | copper chaperone for superoxide dismutase |
| CD79A | CD79a molecule, immunoglobulin-associated alpha |
| CD82 | CD82 molecule |
| CEBPE | CCAAT/enhancer binding protein (C/EBP), epsilon |
| CENPO | centromere protein O |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| CHST12 | carbohydrate (chondroitin 4) sulfotransferase 12 |
| CHST5 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 |
| CPNE7 | copine VII |
| CXORF56 | chromosome X open reading frame 56 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa |
| DLK2 | delta-like 2 homolog (Drosophila) |
| DUSP13 | dual specificity phosphatase 13 |
| ELMO3 | engulfment and cell motility 3 |
| FAM153A | family with sequence similarity 153, member A |
| FAM198B | family with sequence similarity 198, member B |
| FAM76A | family with sequence similarity 76, member A |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FLJ11710 | uncharacterized protein FLJ11710 |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| FYCO1 | FYVE and coiled-coil domain containing 1 |
| GAST | gastrin |
| GJA9 | gap junction protein, alpha 9, 59kDa |
| GLMN | glomulin, FKBP associated protein |
| GPR35 | G protein-coupled receptor 35 |
| GRIP2 | glutamate receptor interacting protein 2 |
| GTF2I | general transcription factor IIi |
| HDAC5 | histone deacetylase 5 |
| HDAC7 | histone deacetylase 7 |
| HELLS | helicase, lymphoid-specific |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HOXC11 | homeobox C11 |
| HSD17B3 | hydroxysteroid (17-beta) dehydrogenase 3 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
| IL2RG | interleukin 2 receptor, gamma |
| KCNMB2 | potassium channel subfamily M regulatory beta subunit 2 |
| KDM7A | lysine (K)-specific demethylase 7A |
| L2HGDH | L-2-hydroxyglutarate dehydrogenase |
| LILRA6 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 |
| LIMS2 | LIM and senescent cell antigen-like domains 2 |
| LINC00312 | long intergenic non-protein coding RNA 312 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MAPK12 | mitogen-activated protein kinase 12 |
| MAS1 | MAS1 proto-oncogene, G protein-coupled receptor |
| MNT | MAX network transcriptional repressor |
| MPPED1 | metallophosphoesterase domain containing 1 |
| MSX1 | msh homeobox 1 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MVP | major vault protein |
| OMG | oligodendrocyte myelin glycoprotein |
| PAK1IP1 | PAK1 interacting protein 1 |
| PCDHGA1 | protocadherin gamma subfamily A, 1 |
| PEMT | phosphatidylethanolamine N-methyltransferase |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PIGR | polymeric immunoglobulin receptor |
| PKD2L1 | polycystic kidney disease 2-like 1 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma |
| PRMT3 | protein arginine methyltransferase 3 |
| PRODH2 | proline dehydrogenase (oxidase) 2 |
| PROP1 | PROP paired-like homeobox 1 |
| QTRTD1 | queuine tRNA-ribosyltransferase domain containing 1 |
| RAB4B | RAB4B, member RAS oncogene family |
| RBM47 | RNA binding motif protein 47 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RLBP1 | retinaldehyde binding protein 1 |
| RRP1 | ribosomal RNA processing 1 |
| S100P | S100 calcium binding protein P |
| SGK2 | serum/glucocorticoid regulated kinase 2 |
| SH2B3 | SH2B adaptor protein 3 |
| SLC7A9 | solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 |
| STX1A | syntaxin 1A (brain) |
| T | T, brachyury homolog (mouse) |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| TMEM2 | transmembrane protein 2 |
| TSNAX | translin-associated factor X |
| TUBA4B | tubulin, alpha 4b |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 |
| WASF1 | WAS protein family, member 1 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| YAF2 | YY1 associated factor 2 |
| ZFHX2 | zinc finger homeobox 2 |