sulindac-1815 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

197 genes differentially expressed following the sulindac-1815 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKAP7 A kinase (PRKA) anchor protein 7
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
APOL2 apolipoprotein L, 2
ARF6 ADP-ribosylation factor 6
ARHGAP6 Rho GTPase activating protein 6
ASB1 ankyrin repeat and SOCS box containing 1
ASPH aspartate beta-hydroxylase
ATXN2L ataxin 2-like
CD46 CD46 molecule, complement regulatory protein
CD47 CD47 molecule
CD58 CD58 molecule
CDV3 CDV3 homolog (mouse)
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
CNOT8 CCR4-NOT transcription complex, subunit 8
CTNS cystinosin, lysosomal cystine transporter
CXCL3 chemokine (C-X-C motif) ligand 3
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DHRS7 dehydrogenase/reductase (SDR family) member 7
DLL3 delta-like 3 (Drosophila)
DPP4 dipeptidyl-peptidase 4
DTX2 deltex 2, E3 ubiquitin ligase
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EML3 echinoderm microtubule associated protein like 3
EPHB2 EPH receptor B2
FCF1 FCF1 rRNA-processing protein
FCHSD2 FCH and double SH3 domains 2
FSCN1 fascin actin-bundling protein 1
GDAP1 ganglioside induced differentiation associated protein 1
GTF2F1 general transcription factor IIF, polypeptide 1, 74kDa
HEG1 heart development protein with EGF-like domains 1
HMOX1 heme oxygenase 1
HOXA1 homeobox A1
IFNAR1 interferon (alpha, beta and omega) receptor 1
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
ITGA6 integrin, alpha 6
IVNS1ABP influenza virus NS1A binding protein
KAZN kazrin, periplakin interacting protein
KCTD7 potassium channel tetramerization domain containing 7
KIF3C kinesin family member 3C
KLK7 kallikrein-related peptidase 7
KRIT1 KRIT1, ankyrin repeat containing
LMAN1 lectin, mannose-binding, 1
LMNA lamin A/C
MAT2A methionine adenosyltransferase II, alpha
MAX MYC associated factor X
METTL3 methyltransferase like 3
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NEK2 NIMA-related kinase 2
NF1 neurofibromin 1
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NOTCH2 notch 2
NPEPL1 aminopeptidase-like 1
PEG3 paternally expressed 3
PICALM phosphatidylinositol binding clathrin assembly protein
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
POT1 protection of telomeres 1
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PREPL prolyl endopeptidase-like
PRKCH protein kinase C, eta
PTP4A3 protein tyrosine phosphatase type IVA, member 3
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic)
RAB6A RAB6A, member RAS oncogene family
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
RBMS3 RNA binding motif, single stranded interacting protein 3
RDX radixin
RFC3 replication factor C (activator 1) 3, 38kDa
RPUSD2 RNA pseudouridylate synthase domain containing 2
S100A13 S100 calcium binding protein A13
SGPP1 sphingosine-1-phosphate phosphatase 1
SIDT2 SID1 transmembrane family, member 2
SNAP23 synaptosomal-associated protein, 23kDa
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome)
SQLE squalene epoxidase
SS18 synovial sarcoma translocation, chromosome 18
TBCD tubulin folding cofactor D
TCAF1 TRPM8 channel-associated factor 1
TCF3 transcription factor 3
TEX261 testis expressed 261
TMED2 transmembrane emp24 domain trafficking protein 2
TMEM194A transmembrane protein 194A
TMEM254 transmembrane protein 254
TMEM53 transmembrane protein 53
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TNS2 tensin 2
TRAF4 TNF receptor-associated factor 4
TRIM52 tripartite motif containing 52
TRIO trio Rho guanine nucleotide exchange factor
TSPAN3 tetraspanin 3
TUBA3C tubulin, alpha 3c
TUBA3D tubulin, alpha 3d
USP24 ubiquitin specific peptidase 24
UTRN utrophin
VEGFA vascular endothelial growth factor A
ZNF10 zinc finger protein 10
ZNF137P zinc finger protein 137, pseudogene
ZNF329 zinc finger protein 329

decreased expression

Symbol Name
AFAP1 actin filament associated protein 1
ALPK1 alpha-kinase 1
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARSJ arylsulfatase family, member J
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BAHD1 bromo adjacent homology domain containing 1
C7ORF43 chromosome 7 open reading frame 43
C9ORF114 chromosome 9 open reading frame 114
CCNJL cyclin J-like
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CGREF1 cell growth regulator with EF-hand domain 1
CHKB choline kinase beta
CLCN2 chloride channel, voltage-sensitive 2
DET1 de-etiolated homolog 1 (Arabidopsis)
DNAL4 dynein, axonemal, light chain 4
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
FAM50B family with sequence similarity 50, member B
FBRS fibrosin
FKBP10 FK506 binding protein 10, 65 kDa
FKBPL FK506 binding protein like
FLJ22184
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GPR1 G protein-coupled receptor 1
GRWD1 glutamate-rich WD repeat containing 1
HDAC7 histone deacetylase 7
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HOXB5 homeobox B5
ICK intestinal cell (MAK-like) kinase
JAM3 junctional adhesion molecule 3
JUNB jun B proto-oncogene
KAT2B K(lysine) acetyltransferase 2B
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KDM5C lysine (K)-specific demethylase 5C
KIFC3 kinesin family member C3
KLF7 Kruppel-like factor 7 (ubiquitous)
KLHDC4 kelch domain containing 4
KLHL36 kelch-like family member 36
LIMS2 LIM and senescent cell antigen-like domains 2
LZTR1 leucine-zipper-like transcription regulator 1
MAMLD1 mastermind-like domain containing 1
MANSC1 MANSC domain containing 1
MAP9 microtubule-associated protein 9
MAPK12 mitogen-activated protein kinase 12
MITF microphthalmia-associated transcription factor
MPI mannose phosphate isomerase
N6AMT1 N-6 adenine-specific DNA methyltransferase 1 (putative)
NARFL nuclear prelamin A recognition factor-like
NCS1 neuronal calcium sensor 1
NT5DC3 5'-nucleotidase domain containing 3
OCEL1 occludin/ELL domain containing 1
OLFML2A olfactomedin-like 2A
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PARP16 poly (ADP-ribose) polymerase family, member 16
PCBP4 poly(rC) binding protein 4
PCOLCE procollagen C-endopeptidase enhancer
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PTK6 protein tyrosine kinase 6
PTTG3P pituitary tumor-transforming 3, pseudogene
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RIN1 Ras and Rab interactor 1
RNF144A ring finger protein 144A
RSF1 remodeling and spacing factor 1
RUNX1-IT1 RUNX1 intronic transcript 1
SALL2 spalt-like transcription factor 2
SCML2 sex comb on midleg-like 2 (Drosophila)
SDC3 syndecan 3
SH2D2A SH2 domain containing 2A
SH3GL1 SH3-domain GRB2-like 1
SLC12A8 solute carrier family 12, member 8
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SPATA2L spermatogenesis associated 2-like
STAG3 stromal antigen 3
TBX19 T-box 19
TH tyrosine hydroxylase
TMEM242 transmembrane protein 242
TMOD3 tropomodulin 3 (ubiquitous)
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TOM1 target of myb1 (chicken)
TRPV1 transient receptor potential cation channel, subfamily V, member 1
URGCP upregulator of cell proliferation
USP18 ubiquitin specific peptidase 18
USP19 ubiquitin specific peptidase 19
WDR19 WD repeat domain 19
WSCD1 WSC domain containing 1
ZBTB3 zinc finger and BTB domain containing 3
ZMAT5 zinc finger, matrin-type 5
ZNF276 zinc finger protein 276
ZNF32 zinc finger protein 32
ZNF574 zinc finger protein 574
ZNF747 zinc finger protein 747
ZNF813 zinc finger protein 813