| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the sulindac-5103 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 |
| AKAP5 | A kinase (PRKA) anchor protein 5 |
| APC | adenomatous polyposis coli |
| ASTN2 | astrotactin 2 |
| ATP11A | ATPase, class VI, type 11A |
| ATXN7L1 | ataxin 7-like 1 |
| AURKC | aurora kinase C |
| BCL2 | B-cell CLL/lymphoma 2 |
| BMP1 | bone morphogenetic protein 1 |
| BRF1 | BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit |
| BTBD7 | BTB (POZ) domain containing 7 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 |
| COL8A1 | collagen, type VIII, alpha 1 |
| COQ7 | coenzyme Q7 homolog, ubiquinone (yeast) |
| CRMP1 | collapsin response mediator protein 1 |
| CSF1 | colony stimulating factor 1 (macrophage) |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DCTN1 | dynactin 1 |
| DCX | doublecortin |
| DHODH | dihydroorotate dehydrogenase (quinone) |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| EGR1 | early growth response 1 |
| ELK4 | ELK4, ETS-domain protein (SRF accessory protein 1) |
| EXOC6B | exocyst complex component 6B |
| FAM63B | family with sequence similarity 63, member B |
| FBXO11 | F-box protein 11 |
| FGFR1 | fibroblast growth factor receptor 1 |
| GLP1R | glucagon-like peptide 1 receptor |
| GPR1 | G protein-coupled receptor 1 |
| GTF2H2B | general transcription factor IIH, polypeptide 2B (pseudogene) |
| HCRP1 | hepatocellular carcinoma-related HCRP1 |
| HEG1 | heart development protein with EGF-like domains 1 |
| HN1L | hematological and neurological expressed 1-like |
| HNF1B | HNF1 homeobox B |
| HOMER3 | homer scaffolding protein 3 |
| HSPA12A | heat shock 70kDa protein 12A |
| IFITM1 | interferon induced transmembrane protein 1 |
| IL6 | interleukin 6 |
| INO80D | INO80 complex subunit D |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| KDM8 | lysine (K)-specific demethylase 8 |
| KIAA0485 | uncharacterized LOC57235 |
| KLHL22 | kelch-like family member 22 |
| KRT34 | keratin 34, type I |
| LAT2 | linker for activation of T cells family, member 2 |
| LINC00260 | long intergenic non-protein coding RNA 260 |
| LOXL2 | lysyl oxidase-like 2 |
| LPCAT4 | lysophosphatidylcholine acyltransferase 4 |
| LRRC8E | leucine rich repeat containing 8 family, member E |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 |
| MCTP2 | multiple C2 domains, transmembrane 2 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
| MPZL1 | myelin protein zero-like 1 |
| MYO1F | myosin IF |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| N4BP2L2-IT2 | N4BPL2 intronic transcript 2 |
| ONECUT2 | one cut homeobox 2 |
| PATZ1 | POZ (BTB) and AT hook containing zinc finger 1 |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PLK4 | polo-like kinase 4 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PRELP | proline/arginine-rich end leucine-rich repeat protein |
| PRKCE | protein kinase C, epsilon |
| PTPRB | protein tyrosine phosphatase, receptor type, B |
| PTRF | polymerase I and transcript release factor |
| PVR | poliovirus receptor |
| PVT1 | Pvt1 oncogene (non-protein coding) |
| RABGAP1 | RAB GTPase activating protein 1 |
| RAD52 | RAD52 homolog (S. cerevisiae) |
| RCN3 | reticulocalbin 3, EF-hand calcium binding domain |
| RPL10 | ribosomal protein L10 |
| RUNX1 | runt-related transcription factor 1 |
| S100A11 | S100 calcium binding protein A11 |
| SAP30 | Sin3A-associated protein, 30kDa |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) |
| TAF5L | TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
| TAPBP | TAP binding protein (tapasin) |
| TBKBP1 | TBK1 binding protein 1 |
| TMEM231 | transmembrane protein 231 |
| TPM2 | tropomyosin 2 (beta) |
| TUBA4B | tubulin, alpha 4b |
| TYRO3 | TYRO3 protein tyrosine kinase |
| UHRF1BP1L | UHRF1 binding protein 1-like |
| URB1 | URB1 ribosome biogenesis 1 homolog (S. cerevisiae) |
| WSB1 | WD repeat and SOCS box containing 1 |
| YIPF4 | Yip1 domain family, member 4 |
| ZBED4 | zinc finger, BED-type containing 4 |
| ZBTB18 | zinc finger and BTB domain containing 18 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 |
| ZFP64 | ZFP64 zinc finger protein |
| ZNF492 | zinc finger protein 492 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
| Symbol | Name |
|---|---|
| ACSF2 | acyl-CoA synthetase family member 2 |
| ADGRB2 | adhesion G protein-coupled receptor B2 |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| APH1B | APH1B gamma secretase subunit |
| APOLD1 | apolipoprotein L domain containing 1 |
| ARHGAP24 | Rho GTPase activating protein 24 |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
| ATP1A3 | ATPase, Na+/K+ transporting, alpha 3 polypeptide |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 |
| BCAS3 | breast carcinoma amplified sequence 3 |
| BCL9 | B-cell CLL/lymphoma 9 |
| BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 |
| BFSP1 | beaded filament structural protein 1, filensin |
| C14ORF105 | chromosome 14 open reading frame 105 |
| C1ORF21 | chromosome 1 open reading frame 21 |
| C6ORF47 | chromosome 6 open reading frame 47 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CAPN15 | calpain 15 |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CHPF | chondroitin polymerizing factor |
| CHRNB1 | cholinergic receptor, nicotinic, beta 1 (muscle) |
| CIDEC | cell death-inducing DFFA-like effector c |
| CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 |
| DLK2 | delta-like 2 homolog (Drosophila) |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| EPHA4 | EPH receptor A4 |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| FAM186A | family with sequence similarity 186, member A |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FRMD8 | FERM domain containing 8 |
| GAS8 | growth arrest-specific 8 |
| GIF | gastric intrinsic factor (vitamin B synthesis) |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HIST1H3F | histone cluster 1, H3f |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| ICOS | inducible T-cell co-stimulator |
| IFNA2 | interferon, alpha 2 |
| IL22 | interleukin 22 |
| IL7R | interleukin 7 receptor |
| KIAA0355 | KIAA0355 |
| KIF13B | kinesin family member 13B |
| KLHL28 | kelch-like family member 28 |
| KLHL36 | kelch-like family member 36 |
| KRT86 | keratin 86, type II |
| LRRC61 | leucine rich repeat containing 61 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MED31 | mediator complex subunit 31 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MUC3A | mucin 3A, cell surface associated |
| MUC3B | mucin 3B, cell surface associated |
| MYH15 | myosin, heavy chain 15 |
| NIPAL2 | NIPA-like domain containing 2 |
| NME5 | NME/NM23 family member 5 |
| NPR3 | natriuretic peptide receptor 3 |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| P2RY1 | purinergic receptor P2Y, G-protein coupled, 1 |
| PARM1 | prostate androgen-regulated mucin-like protein 1 |
| PARP6 | poly (ADP-ribose) polymerase family, member 6 |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PLXNB3 | plexin B3 |
| POLH | polymerase (DNA directed), eta |
| POLL | polymerase (DNA directed), lambda |
| PRKG2 | protein kinase, cGMP-dependent, type II |
| PRSS22 | protease, serine, 22 |
| PTK6 | protein tyrosine kinase 6 |
| QSER1 | glutamine and serine rich 1 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SH2D4A | SH2 domain containing 4A |
| SIRT6 | sirtuin 6 |
| SLC17A2 | solute carrier family 17, member 2 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SLC4A8 | solute carrier family 4, sodium bicarbonate cotransporter, member 8 |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SNPH | syntaphilin |
| STEAP4 | STEAP family member 4 |
| TAGLN3 | transgelin 3 |
| THBS3 | thrombospondin 3 |
| THRB | thyroid hormone receptor, beta |
| TLR2 | toll-like receptor 2 |
| TM6SF1 | transmembrane 6 superfamily member 1 |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 |
| TSPAN1 | tetraspanin 1 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| USB1 | U6 snRNA biogenesis 1 |
| VWA1 | von Willebrand factor A domain containing 1 |
| WDR25 | WD repeat domain 25 |
| YPEL1 | yippee-like 1 (Drosophila) |
| ZNF225 | zinc finger protein 225 |
| ZNF446 | zinc finger protein 446 |