sulindac-5103 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the sulindac-5103 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
AKAP5 A kinase (PRKA) anchor protein 5
APC adenomatous polyposis coli
ASTN2 astrotactin 2
ATP11A ATPase, class VI, type 11A
ATXN7L1 ataxin 7-like 1
AURKC aurora kinase C
BCL2 B-cell CLL/lymphoma 2
BMP1 bone morphogenetic protein 1
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
BTBD7 BTB (POZ) domain containing 7
C22ORF46 chromosome 22 open reading frame 46
CAPZB capping protein (actin filament) muscle Z-line, beta
CD40 CD40 molecule, TNF receptor superfamily member 5
COL8A1 collagen, type VIII, alpha 1
COQ7 coenzyme Q7 homolog, ubiquinone (yeast)
CRMP1 collapsin response mediator protein 1
CSF1 colony stimulating factor 1 (macrophage)
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DCTN1 dynactin 1
DCX doublecortin
DHODH dihydroorotate dehydrogenase (quinone)
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
EGR1 early growth response 1
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1)
EXOC6B exocyst complex component 6B
FAM63B family with sequence similarity 63, member B
FBXO11 F-box protein 11
FGFR1 fibroblast growth factor receptor 1
GLP1R glucagon-like peptide 1 receptor
GPR1 G protein-coupled receptor 1
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
HCRP1 hepatocellular carcinoma-related HCRP1
HEG1 heart development protein with EGF-like domains 1
HN1L hematological and neurological expressed 1-like
HNF1B HNF1 homeobox B
HOMER3 homer scaffolding protein 3
HSPA12A heat shock 70kDa protein 12A
IFITM1 interferon induced transmembrane protein 1
IL6 interleukin 6
INO80D INO80 complex subunit D
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
KDM8 lysine (K)-specific demethylase 8
KIAA0485 uncharacterized LOC57235
KLHL22 kelch-like family member 22
KRT34 keratin 34, type I
LAT2 linker for activation of T cells family, member 2
LINC00260 long intergenic non-protein coding RNA 260
LOXL2 lysyl oxidase-like 2
LPCAT4 lysophosphatidylcholine acyltransferase 4
LRRC8E leucine rich repeat containing 8 family, member E
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MCTP2 multiple C2 domains, transmembrane 2
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MPZL1 myelin protein zero-like 1
MYO1F myosin IF
N4BP2L2 NEDD4 binding protein 2-like 2
N4BP2L2-IT2 N4BPL2 intronic transcript 2
ONECUT2 one cut homeobox 2
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PDGFA platelet-derived growth factor alpha polypeptide
PLK4 polo-like kinase 4
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PRELP proline/arginine-rich end leucine-rich repeat protein
PRKCE protein kinase C, epsilon
PTPRB protein tyrosine phosphatase, receptor type, B
PTRF polymerase I and transcript release factor
PVR poliovirus receptor
PVT1 Pvt1 oncogene (non-protein coding)
RABGAP1 RAB GTPase activating protein 1
RAD52 RAD52 homolog (S. cerevisiae)
RCN3 reticulocalbin 3, EF-hand calcium binding domain
RPL10 ribosomal protein L10
RUNX1 runt-related transcription factor 1
S100A11 S100 calcium binding protein A11
SAP30 Sin3A-associated protein, 30kDa
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TAPBP TAP binding protein (tapasin)
TBKBP1 TBK1 binding protein 1
TMEM231 transmembrane protein 231
TPM2 tropomyosin 2 (beta)
TUBA4B tubulin, alpha 4b
TYRO3 TYRO3 protein tyrosine kinase
UHRF1BP1L UHRF1 binding protein 1-like
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
WSB1 WD repeat and SOCS box containing 1
YIPF4 Yip1 domain family, member 4
ZBED4 zinc finger, BED-type containing 4
ZBTB18 zinc finger and BTB domain containing 18
ZFP36L1 ZFP36 ring finger protein-like 1
ZFP64 ZFP64 zinc finger protein
ZNF492 zinc finger protein 492
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ACSF2 acyl-CoA synthetase family member 2
ADGRB2 adhesion G protein-coupled receptor B2
ANP32A-IT1 ANP32A intronic transcript 1
APH1B APH1B gamma secretase subunit
APOLD1 apolipoprotein L domain containing 1
ARHGAP24 Rho GTPase activating protein 24
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BCAS3 breast carcinoma amplified sequence 3
BCL9 B-cell CLL/lymphoma 9
BDH1 3-hydroxybutyrate dehydrogenase, type 1
BFSP1 beaded filament structural protein 1, filensin
C14ORF105 chromosome 14 open reading frame 105
C1ORF21 chromosome 1 open reading frame 21
C6ORF47 chromosome 6 open reading frame 47
C7ORF43 chromosome 7 open reading frame 43
CAPN15 calpain 15
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CHPF chondroitin polymerizing factor
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CIDEC cell death-inducing DFFA-like effector c
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
DLK2 delta-like 2 homolog (Drosophila)
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EPHA4 EPH receptor A4
EYA3 EYA transcriptional coactivator and phosphatase 3
FAM186A family with sequence similarity 186, member A
FBXL7 F-box and leucine-rich repeat protein 7
FRMD8 FERM domain containing 8
GAS8 growth arrest-specific 8
GIF gastric intrinsic factor (vitamin B synthesis)
GPRIN2 G protein regulated inducer of neurite outgrowth 2
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIST1H3F histone cluster 1, H3f
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
ICOS inducible T-cell co-stimulator
IFNA2 interferon, alpha 2
IL22 interleukin 22
IL7R interleukin 7 receptor
KIAA0355 KIAA0355
KIF13B kinesin family member 13B
KLHL28 kelch-like family member 28
KLHL36 kelch-like family member 36
KRT86 keratin 86, type II
LRRC61 leucine rich repeat containing 61
LY6G6C lymphocyte antigen 6 complex, locus G6C
MAST3 microtubule associated serine/threonine kinase 3
MBNL3 muscleblind-like splicing regulator 3
MED31 mediator complex subunit 31
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MUC3A mucin 3A, cell surface associated
MUC3B mucin 3B, cell surface associated
MYH15 myosin, heavy chain 15
NIPAL2 NIPA-like domain containing 2
NME5 NME/NM23 family member 5
NPR3 natriuretic peptide receptor 3
OVGP1 oviductal glycoprotein 1, 120kDa
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
PARM1 prostate androgen-regulated mucin-like protein 1
PARP6 poly (ADP-ribose) polymerase family, member 6
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PLXNB3 plexin B3
POLH polymerase (DNA directed), eta
POLL polymerase (DNA directed), lambda
PRKG2 protein kinase, cGMP-dependent, type II
PRSS22 protease, serine, 22
PTK6 protein tyrosine kinase 6
QSER1 glutamine and serine rich 1
RPL13P5 ribosomal protein L13 pseudogene 5
SAYSD1 SAYSVFN motif domain containing 1
SCUBE3 signal peptide, CUB domain, EGF-like 3
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SH2D4A SH2 domain containing 4A
SIRT6 sirtuin 6
SLC17A2 solute carrier family 17, member 2
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SNPH syntaphilin
STEAP4 STEAP family member 4
TAGLN3 transgelin 3
THBS3 thrombospondin 3
THRB thyroid hormone receptor, beta
TLR2 toll-like receptor 2
TM6SF1 transmembrane 6 superfamily member 1
TPRA1 transmembrane protein, adipocyte asscociated 1
TSPAN1 tetraspanin 1
TTLL1 tubulin tyrosine ligase-like family member 1
USB1 U6 snRNA biogenesis 1
VWA1 von Willebrand factor A domain containing 1
WDR25 WD repeat domain 25
YPEL1 yippee-like 1 (Drosophila)
ZNF225 zinc finger protein 225
ZNF446 zinc finger protein 446