sulmazole-2153 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the sulmazole-2153 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACYP1 acylphosphatase 1, erythrocyte (common) type
ADARB1 adenosine deaminase, RNA-specific, B1
ADD2 adducin 2 (beta)
AEN apoptosis enhancing nuclease
AHNAK2 AHNAK nucleoprotein 2
APP amyloid beta (A4) precursor protein
ATP13A2 ATPase type 13A2
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
ATP9B ATPase, class II, type 9B
BTN3A1 butyrophilin, subfamily 3, member A1
BTNL3 butyrophilin-like 3
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CAMK4 calcium/calmodulin-dependent protein kinase IV
CAMKV CaM kinase-like vesicle-associated
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2
CCDC57 coiled-coil domain containing 57
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CLGN calmegin
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CRY2 cryptochrome circadian clock 2
CSF1 colony stimulating factor 1 (macrophage)
CTSZ cathepsin Z
CXCL6 chemokine (C-X-C motif) ligand 6
CXCR3 chemokine (C-X-C motif) receptor 3
EFR3B EFR3 homolog B (S. cerevisiae)
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1)
ENG endoglin
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
FAM49B family with sequence similarity 49, member B
FAM65A family with sequence similarity 65, member A
FBXO2 F-box protein 2
FGFR1 fibroblast growth factor receptor 1
FZD3 frizzled class receptor 3
GAS6 growth arrest-specific 6
GDAP1 ganglioside induced differentiation associated protein 1
GNG3 guanine nucleotide binding protein (G protein), gamma 3
H2AFX H2A histone family, member X
HABP4 hyaluronan binding protein 4
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
HOXC10 homeobox C10
HSPG2 heparan sulfate proteoglycan 2
IL5RA interleukin 5 receptor, alpha
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIF5C kinesin family member 5C
KRT6B keratin 6B, type II
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAP1A microtubule-associated protein 1A
MAP4 microtubule-associated protein 4
MAP7 microtubule-associated protein 7
MCAM melanoma cell adhesion molecule
MED25 mediator complex subunit 25
MORN1 MORN repeat containing 1
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NCOA2 nuclear receptor coactivator 2
NEK9 NIMA-related kinase 9
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NMT2 N-myristoyltransferase 2
NPEPL1 aminopeptidase-like 1
NUDT7 nudix (nucleoside diphosphate linked moiety X)-type motif 7
NUP50 nucleoporin 50kDa
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
PCBP4 poly(rC) binding protein 4
PDLIM7 PDZ and LIM domain 7 (enigma)
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
PLEC plectin
PPARD peroxisome proliferator-activated receptor delta
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
RECQL5 RecQ protein-like 5
RFX2 regulatory factor X, 2 (influences HLA class II expression)
RXRB retinoid X receptor, beta
SLC13A3 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC35G2 solute carrier family 35, member G2
SPHK2 sphingosine kinase 2
SPTBN1 spectrin, beta, non-erythrocytic 1
STRA6 stimulated by retinoic acid 6
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
TAPT1 transmembrane anterior posterior transformation 1
TECPR2 tectonin beta-propeller repeat containing 2
TMC7 transmembrane channel-like 7
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
TRAF4 TNF receptor-associated factor 4
TSC22D3 TSC22 domain family, member 3
TSKU tsukushi, small leucine rich proteoglycan
TULP3 tubby like protein 3
UBOX5 U-box domain containing 5
USB1 U6 snRNA biogenesis 1
USP18 ubiquitin specific peptidase 18
ZBTB17 zinc finger and BTB domain containing 17
ZC3H13 zinc finger CCCH-type containing 13
ZC3H7B zinc finger CCCH-type containing 7B
ZER1 zyg-11 related, cell cycle regulator
ZNF668 zinc finger protein 668
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
ASGR2 asialoglycoprotein receptor 2
ATAT1 alpha tubulin acetyltransferase 1
BHLHE41 basic helix-loop-helix family, member e41
BNC2 basonuclin 2
BTBD18 BTB (POZ) domain containing 18
C16ORF59 chromosome 16 open reading frame 59
C22ORF46 chromosome 22 open reading frame 46
C5AR1 complement component 5a receptor 1
CA11 carbonic anhydrase XI
CD3D CD3d molecule, delta (CD3-TCR complex)
CD70 CD70 molecule
CEP70 centrosomal protein 70kDa
CNR2 cannabinoid receptor 2 (macrophage)
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DEAF1 DEAF1 transcription factor
DENND5B DENN/MADD domain containing 5B
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DGKG diacylglycerol kinase, gamma 90kDa
DOC2A double C2-like domains, alpha
ELP6 elongator acetyltransferase complex subunit 6
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
ETV4 ets variant 4
FBP1 fructose-1,6-bisphosphatase 1
FDXR ferredoxin reductase
FKBPL FK506 binding protein like
FOXN2 forkhead box N2
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GJA1 gap junction protein, alpha 1, 43kDa
GLI3 GLI family zinc finger 3
GPX2 glutathione peroxidase 2
GSTA3 glutathione S-transferase alpha 3
GSTT1 glutathione S-transferase theta 1
HIST1H2AE histone cluster 1, H2ae
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
IL1R2 interleukin 1 receptor, type II
INO80D INO80 complex subunit D
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KDM5C lysine (K)-specific demethylase 5C
KLF1 Kruppel-like factor 1 (erythroid)
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LTC4S leukotriene C4 synthase
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAK male germ cell-associated kinase
MBNL3 muscleblind-like splicing regulator 3
MEFV Mediterranean fever
MYL5 myosin, light chain 5, regulatory
MYOZ3 myozenin 3
N6AMT1 N-6 adenine-specific DNA methyltransferase 1 (putative)
NCALD neurocalcin delta
NECAB3 N-terminal EF-hand calcium binding protein 3
NHEJ1 nonhomologous end-joining factor 1
NOD2 nucleotide-binding oligomerization domain containing 2
PADI1 peptidyl arginine deiminase, type I
PECR peroxisomal trans-2-enoyl-CoA reductase
PNOC prepronociceptin
PODNL1 podocan-like 1
POLL polymerase (DNA directed), lambda
POM121L2 POM121 transmembrane nucleoporin-like 2
PTTG3P pituitary tumor-transforming 3, pseudogene
RAB13 RAB13, member RAS oncogene family
RAB33A RAB33A, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAP1GAP2 RAP1 GTPase activating protein 2
RETN resistin
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RPL13P5 ribosomal protein L13 pseudogene 5
RRAS related RAS viral (r-ras) oncogene homolog
SCG5 secretogranin V
SCGB2A2 secretoglobin, family 2A, member 2
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
SH3BGR SH3 domain binding glutamate-rich protein
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC12A8 solute carrier family 12, member 8
SLC22A14 solute carrier family 22, member 14
SLPI secretory leukocyte peptidase inhibitor
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SOCS7 suppressor of cytokine signaling 7
SOX12 SRY (sex determining region Y)-box 12
TBC1D19 TBC1 domain family, member 19
TCTN1 tectonic family member 1
TEX40 testis expressed 40
TFF2 trefoil factor 2
TOR4A torsin family 4, member A
TPCN1 two pore segment channel 1
TRPS1 trichorhinophalangeal syndrome I
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TUBA3C tubulin, alpha 3c
WDR33 WD repeat domain 33
WNT10B wingless-type MMTV integration site family, member 10B
YY2 YY2 transcription factor
ZBTB38 zinc finger and BTB domain containing 38
ZC3H3 zinc finger CCCH-type containing 3
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF219 zinc finger protein 219
ZNF350 zinc finger protein 350
ZNF749 zinc finger protein 749