sulmazole-4127 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the sulmazole-4127 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ADAP2 ArfGAP with dual PH domains 2
ADGRL1 adhesion G protein-coupled receptor L1
ADGRL3 adhesion G protein-coupled receptor L3
AKAP8L A kinase (PRKA) anchor protein 8-like
ALOX5 arachidonate 5-lipoxygenase
ARG1 arginase 1
ASPH aspartate beta-hydroxylase
ATN1 atrophin 1
ATP10B ATPase, class V, type 10B
BAZ1B bromodomain adjacent to zinc finger domain, 1B
C4ORF29 chromosome 4 open reading frame 29
CAV3 caveolin 3
CCZ1 CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
CD101 CD101 molecule
CDY1 chromodomain protein, Y-linked, 1
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
COL10A1 collagen, type X, alpha 1
CRP C-reactive protein, pentraxin-related
DAPK3 death-associated protein kinase 3
DFNB31 deafness, autosomal recessive 31
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
EFNB3 ephrin-B3
ELL2 elongation factor, RNA polymerase II, 2
EPHB6 EPH receptor B6
EVC Ellis van Creveld protein
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GAS7 growth arrest-specific 7
GPR137 G protein-coupled receptor 137
GPR85 G protein-coupled receptor 85
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GREB1 growth regulation by estrogen in breast cancer 1
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GUCA1B guanylate cyclase activator 1B (retina)
H2AFX H2A histone family, member X
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HPX hemopexin
HRH1 histamine receptor H1
HSPG2 heparan sulfate proteoglycan 2
ICA1 islet cell autoantigen 1, 69kDa
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KIAA1107 KIAA1107
KIAA1456 KIAA1456
KRT75 keratin 75, type II
LOC100131532 uncharacterized LOC100131532
LOC644450 uncharacterized LOC644450
LOXL3 lysyl oxidase-like 3
MAP2K5 mitogen-activated protein kinase kinase 5
MAP2K7 mitogen-activated protein kinase kinase 7
MEFV Mediterranean fever
MFAP5 microfibrillar associated protein 5
MOB3B MOB kinase activator 3B
MSI1 musashi RNA-binding protein 1
NEU3 sialidase 3 (membrane sialidase)
NR1H4 nuclear receptor subfamily 1, group H, member 4
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
NUDCD3 NudC domain containing 3
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OSGIN2 oxidative stress induced growth inhibitor family member 2
PAPPA2 pappalysin 2
PARP11 poly (ADP-ribose) polymerase family, member 11
PAWR PRKC, apoptosis, WT1, regulator
PCNX pecanex homolog (Drosophila)
PDGFD platelet derived growth factor D
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PLIN2 perilipin 2
POLQ polymerase (DNA directed), theta
PQLC2 PQ loop repeat containing 2
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RPH3A rabphilin 3A
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
SAYSD1 SAYSVFN motif domain containing 1
SH3BP2 SH3-domain binding protein 2
SH3GL3 SH3-domain GRB2-like 3
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNED1 sushi, nidogen and EGF-like domains 1
SPRR2B small proline-rich protein 2B
SRPX2 sushi-repeat containing protein, X-linked 2
SSX3 synovial sarcoma, X breakpoint 3
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2
SYNE1 spectrin repeat containing, nuclear envelope 1
TEX14 testis expressed 14
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TGFB2 transforming growth factor, beta 2
TIMP3 TIMP metallopeptidase inhibitor 3
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TTC9 tetratricopeptide repeat domain 9
TUBGCP2 tubulin, gamma complex associated protein 2
USP29 ubiquitin specific peptidase 29
VAV2 vav 2 guanine nucleotide exchange factor
VAX2 ventral anterior homeobox 2
ZDHHC17 zinc finger, DHHC-type containing 17
ZNF639 zinc finger protein 639

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ALOX15 arachidonate 15-lipoxygenase
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARMC4 armadillo repeat containing 4
ATF3 activating transcription factor 3
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
B9D2 B9 protein domain 2
C19ORF73 chromosome 19 open reading frame 73
C1ORF21 chromosome 1 open reading frame 21
C1QB complement component 1, q subcomponent, B chain
C8ORF60 chromosome 8 open reading frame 60
CARF calcium responsive transcription factor
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD83 CD83 molecule
CEL carboxyl ester lipase
CFAP45 cilia and flagella associated protein 45
CIDEB cell death-inducing DFFA-like effector b
CLSTN2 calsyntenin 2
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CPA4 carboxypeptidase A4
CPED1 cadherin-like and PC-esterase domain containing 1
CRMP1 collapsin response mediator protein 1
CTRL chymotrypsin-like
DGAT1 diacylglycerol O-acyltransferase 1
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAL4 dynein, axonemal, light chain 4
DSCAM Down syndrome cell adhesion molecule
DVL1 dishevelled segment polarity protein 1
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EDN1 endothelin 1
ERCC2 excision repair cross-complementation group 2
EXOC6B exocyst complex component 6B
FAAH fatty acid amide hydrolase
FBXO31 F-box protein 31
GALK1 galactokinase 1
GATA4 GATA binding protein 4
GLB1L galactosidase, beta 1-like
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GPR3 G protein-coupled receptor 3
GRTP1 growth hormone regulated TBC protein 1
HIST1H2BN histone cluster 1, H2bn
HP1BP3 heterochromatin protein 1, binding protein 3
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
IBSP integrin-binding sialoprotein
IL11RA interleukin 11 receptor, alpha
IL2RG interleukin 2 receptor, gamma
LGALS4 lectin, galactoside-binding, soluble, 4
LMTK2 lemur tyrosine kinase 2
LOC100131510 uncharacterized LOC100131510
LRP5L low density lipoprotein receptor-related protein 5-like
LTBP2 latent transforming growth factor beta binding protein 2
MIR622 microRNA 622
MMP3 matrix metallopeptidase 3
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MTA2 metastasis associated 1 family, member 2
NACA2 nascent polypeptide-associated complex alpha subunit 2
NNAT neuronatin
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NOTCH4 notch 4
NPY4R neuropeptide Y receptor Y4
NYNRIN NYN domain and retroviral integrase containing
PCDHGB6 protocadherin gamma subfamily B, 6
PDE8B phosphodiesterase 8B
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PLAC1 placenta-specific 1
POM121L2 POM121 transmembrane nucleoporin-like 2
PRAMEF11 PRAME family member 11
PRR4 proline rich 4 (lacrimal)
PXDC1 PX domain containing 1
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RFXAP regulatory factor X-associated protein
RHOBTB2 Rho-related BTB domain containing 2
RNF122 ring finger protein 122
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RPL10L ribosomal protein L10-like
S100A9 S100 calcium binding protein A9
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SETD1A SET domain containing 1A
SLC17A2 solute carrier family 17, member 2
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SPRR1B small proline-rich protein 1B
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
STAG3 stromal antigen 3
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TBC1D17 TBC1 domain family, member 17
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TEX40 testis expressed 40
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TTLL4 tubulin tyrosine ligase-like family member 4
ULBP2 UL16 binding protein 2
USB1 U6 snRNA biogenesis 1
VPS9D1 VPS9 domain containing 1
XAB2 XPA binding protein 2
XDH xanthine dehydrogenase
ZBTB44 zinc finger and BTB domain containing 44
ZNF41 zinc finger protein 41