suloctidil-1297 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the suloctidil-1297 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAR adenosine deaminase, RNA-specific
AIM2 absent in melanoma 2
APOL6 apolipoprotein L, 6
AXL AXL receptor tyrosine kinase
BST2 bone marrow stromal cell antigen 2
C19ORF66 chromosome 19 open reading frame 66
CCL2 chemokine (C-C motif) ligand 2
CCL4 chemokine (C-C motif) ligand 4
CCL8 chemokine (C-C motif) ligand 8
CCNA1 cyclin A1
CCR1 chemokine (C-C motif) receptor 1
CD70 CD70 molecule
CMTR1 cap methyltransferase 1
CSF1 colony stimulating factor 1 (macrophage)
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DSP desmoplakin
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EXT1 exostosin glycosyltransferase 1
GBP2 guanylate binding protein 2, interferon-inducible
GCLM glutamate-cysteine ligase, modifier subunit
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HMOX1 heme oxygenase 1
IFI16 interferon, gamma-inducible protein 16
IFI35 interferon-induced protein 35
IFI44 interferon-induced protein 44
IFI44L interferon-induced protein 44-like
IFI6 interferon, alpha-inducible protein 6
IFIH1 interferon induced with helicase C domain 1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IFITM1 interferon induced transmembrane protein 1
IFNB1 interferon, beta 1, fibroblast
IL1RN interleukin 1 receptor antagonist
IL24 interleukin 24
IRF7 interferon regulatory factor 7
IRF9 interferon regulatory factor 9
ISG15 ISG15 ubiquitin-like modifier
ISG20 interferon stimulated exonuclease gene 20kDa
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
KIAA0754 KIAA0754
KYNU kynureninase
LAP3 leucine aminopeptidase 3
LPAR6 lysophosphatidic acid receptor 6
LY6E lymphocyte antigen 6 complex, locus E
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1M metallothionein 1M
MT1X metallothionein 1X
MT2A metallothionein 2A
MX1 MX dynamin-like GTPase 1
MX2 MX dynamin-like GTPase 2
MYD88 myeloid differentiation primary response 88
N4BP1 NEDD4 binding protein 1
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OASL 2'-5'-oligoadenylate synthetase-like
PARP12 poly (ADP-ribose) polymerase family, member 12
PHF11 PHD finger protein 11
PLSCR1 phospholipid scramblase 1
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RIN2 Ras and Rab interactor 2
RSAD2 radical S-adenosyl methionine domain containing 2
RTP4 receptor (chemosensory) transporter protein 4
SAMD9 sterile alpha motif domain containing 9
SAT1 spermidine/spermine N1-acetyltransferase 1
SLC12A8 solute carrier family 12, member 8
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SP110 SP110 nuclear body protein
SP140L SP140 nuclear body protein-like
SPATS2L spermatogenesis associated, serine-rich 2-like
STAP1 signal transducing adaptor family member 1
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT2 signal transducer and activator of transcription 2, 113kDa
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TFEC transcription factor EC
THBS1 thrombospondin 1
TMEM140 transmembrane protein 140
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TREX1 three prime repair exonuclease 1
TRIM21 tripartite motif containing 21
TRIM22 tripartite motif containing 22
TRIM5 tripartite motif containing 5
TYMP thymidine phosphorylase
UBE2L6 ubiquitin-conjugating enzyme E2L 6
USP18 ubiquitin specific peptidase 18
XAF1 XIAP associated factor 1
ZC3HAV1 zinc finger CCCH-type, antiviral 1
ZCCHC2 zinc finger, CCHC domain containing 2

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ADM adrenomedullin
BAHD1 bromo adjacent homology domain containing 1
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide
C10ORF2 chromosome 10 open reading frame 2
C10ORF88 chromosome 10 open reading frame 88
C12ORF29 chromosome 12 open reading frame 29
C1ORF21 chromosome 1 open reading frame 21
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CCNE1 cyclin E1
CCNE2 cyclin E2
CD3EAP CD3e molecule, epsilon associated protein
CENPQ centromere protein Q
CHST10 carbohydrate sulfotransferase 10
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CTSG cathepsin G
DCPS decapping enzyme, scavenger
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
FAM57A family with sequence similarity 57, member A
FPGS folylpolyglutamate synthase
FURIN furin (paired basic amino acid cleaving enzyme)
GCHFR GTP cyclohydrolase I feedback regulator
GEMIN4 gem (nuclear organelle) associated protein 4
GNL2 guanine nucleotide binding protein-like 2 (nucleolar)
GPR65 G protein-coupled receptor 65
GUF1 GUF1 GTPase homolog (S. cerevisiae)
HILPDA hypoxia inducible lipid droplet-associated
HOPX HOP homeobox
HP haptoglobin
HRAS Harvey rat sarcoma viral oncogene homolog
HRSP12 heat-responsive protein 12
HSPA4L heat shock 70kDa protein 4-like
IL4R interleukin 4 receptor
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
ITGB7 integrin, beta 7
ITPKB inositol-trisphosphate 3-kinase B
KAT2A K(lysine) acetyltransferase 2A
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
LOC202181 SUMO-interacting motifs containing 1 pseudogene
MAGEF1 melanoma antigen family F1
MAN2A1 mannosidase, alpha, class 2A, member 1
MAPKAP1 mitogen-activated protein kinase associated protein 1
MCRS1 microspherule protein 1
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MOCOS molybdenum cofactor sulfurase
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
MXD3 MAX dimerization protein 3
MYBBP1A MYB binding protein (P160) 1a
MYLIP myosin regulatory light chain interacting protein
NDE1 nudE neurodevelopment protein 1
NMB neuromedin B
NMD3 NMD3 ribosome export adaptor
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor
NT5M 5',3'-nucleotidase, mitochondrial
NTSR1 neurotensin receptor 1 (high affinity)
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
PCID2 PCI domain containing 2
PLEKHJ1 pleckstrin homology domain containing, family J member 1
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
PTCD2 pentatricopeptide repeat domain 2
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae)
RRP1 ribosomal RNA processing 1
RWDD3 RWD domain containing 3
SAC3D1 SAC3 domain containing 1
SCAI suppressor of cancer cell invasion
SCML2 sex comb on midleg-like 2 (Drosophila)
SERINC5 serine incorporator 5
SETD6 SET domain containing 6
SHPK sedoheptulokinase
SIRT7 sirtuin 7
SLC17A9 solute carrier family 17 (vesicular nucleotide transporter), member 9
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SOHLH2 spermatogenesis and oogenesis specific basic helix-loop-helix 2
TERT telomerase reverse transcriptase
TESC tescalcin
THEM6 thioesterase superfamily member 6
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14
TOLLIP toll interacting protein
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast)
TUSC2 tumor suppressor candidate 2
TXNL4B thioredoxin-like 4B
UBQLN4 ubiquilin 4
UNG uracil-DNA glycosylase
VSIG4 V-set and immunoglobulin domain containing 4
WDR3 WD repeat domain 3
XPO4 exportin 4
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZBTB44 zinc finger and BTB domain containing 44
ZC3H12A zinc finger CCCH-type containing 12A
ZNF248 zinc finger protein 248
ZNF665 zinc finger protein 665