suloctidil-5021 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the suloctidil-5021 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ALDOB aldolase B, fructose-bisphosphate
ANG angiogenin, ribonuclease, RNase A family, 5
ATF3 activating transcription factor 3
BHLHE40 basic helix-loop-helix family, member e40
CDY1 chromodomain protein, Y-linked, 1
CGA glycoprotein hormones, alpha polypeptide
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLCN6 chloride channel, voltage-sensitive 6
CPN2 carboxypeptidase N, polypeptide 2
CUL7 cullin 7
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DNAH17 dynein, axonemal, heavy chain 17
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DUSP1 dual specificity phosphatase 1
DUSP4 dual specificity phosphatase 4
DUSP6 dual specificity phosphatase 6
EFNA1 ephrin-A1
EGR1 early growth response 1
EGR2 early growth response 2
EGR3 early growth response 3
EGR4 early growth response 4
EHBP1L1 EH domain binding protein 1-like 1
ERC1 ELKS/RAB6-interacting/CAST family member 1
ETV5 ets variant 5
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GEM GTP binding protein overexpressed in skeletal muscle
GJB3 gap junction protein, beta 3, 31kDa
GRPR gastrin-releasing peptide receptor
HBEGF heparin-binding EGF-like growth factor
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIST1H2BJ histone cluster 1, H2bj
HIST1H3B histone cluster 1, H3b
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
ICAM1 intercellular adhesion molecule 1
IER2 immediate early response 2
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
INHBE inhibin, beta E
IRF1 interferon regulatory factor 1
IRS2 insulin receptor substrate 2
ISG20 interferon stimulated exonuclease gene 20kDa
JUN jun proto-oncogene
KLF2 Kruppel-like factor 2
KLF6 Kruppel-like factor 6
KLHL24 kelch-like family member 24
LPIN1 lipin 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MARS methionyl-tRNA synthetase
MCL1 myeloid cell leukemia 1
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
MT2A metallothionein 2A
MTSS1L metastasis suppressor 1-like
NFIL3 nuclear factor, interleukin 3 regulated
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
OASL 2'-5'-oligoadenylate synthetase-like
OVOL1 ovo-like zinc finger 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PTPN21 protein tyrosine phosphatase, non-receptor type 21
PVT1 Pvt1 oncogene (non-protein coding)
RCAN1 regulator of calcineurin 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RGS20 regulator of G-protein signaling 20
RNASE4 ribonuclease, RNase A family, 4
RND1 Rho family GTPase 1
RNF126P1 ring finger protein 126 pseudogene 1
SAT1 spermidine/spermine N1-acetyltransferase 1
SEC24D SEC24 family member D
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLCO4A1 solute carrier organic anion transporter family, member 4A1
SOX9 SRY (sex determining region Y)-box 9
SRCAP Snf2-related CREBBP activator protein
STX5 syntaxin 5
TEX14 testis expressed 14
TFDP3 transcription factor Dp family, member 3
THOC5 THO complex 5
TLR2 toll-like receptor 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TRIB1 tribbles pseudokinase 1
VAC14 Vac14 homolog (S. cerevisiae)
WIPI1 WD repeat domain, phosphoinositide interacting 1

decreased expression

Symbol Name
ADGRG2 adhesion G protein-coupled receptor G2
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ASAP1-IT1 ASAP1 intronic transcript 1
BTBD2 BTB (POZ) domain containing 2
C5ORF45 chromosome 5 open reading frame 45
C9ORF40 chromosome 9 open reading frame 40
CCNE2 cyclin E2
CCS copper chaperone for superoxide dismutase
CENPJ centromere protein J
CHMP6 charged multivesicular body protein 6
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
COCH cochlin
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
DNAL4 dynein, axonemal, light chain 4
DUSP2 dual specificity phosphatase 2
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
ECHDC3 enoyl CoA hydratase domain containing 3
EFNA3 ephrin-A3
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
EPN3 epsin 3
ERCC4 excision repair cross-complementation group 4
FAM169A family with sequence similarity 169, member A
FAM188A family with sequence similarity 188, member A
FAM63A family with sequence similarity 63, member A
FCHSD2 FCH and double SH3 domains 2
FRMD1 FERM domain containing 1
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11
GAN gigaxonin
GLS2 glutaminase 2 (liver, mitochondrial)
GSTCD glutathione S-transferase, C-terminal domain containing
GUSBP3 glucuronidase, beta pseudogene 3
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
INO80D INO80 complex subunit D
JMJD4 jumonji domain containing 4
KDM5C lysine (K)-specific demethylase 5C
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LOC730101 uncharacterized LOC730101
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MBNL3 muscleblind-like splicing regulator 3
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
METTL8 methyltransferase like 8
MSX1 msh homeobox 1
MUM1 melanoma associated antigen (mutated) 1
N4BP3 NEDD4 binding protein 3
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NME5 NME/NM23 family member 5
NOC3L nucleolar complex associated 3 homolog (S. cerevisiae)
NOTCH1 notch 1
NRSN2 neurensin 2
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PACS1 phosphofurin acidic cluster sorting protein 1
PADI2 peptidyl arginine deiminase, type II
PAQR3 progestin and adipoQ receptor family member III
PCDHB3 protocadherin beta 3
PGBD5 piggyBac transposable element derived 5
PHC1 polyhomeotic homolog 1 (Drosophila)
PPAN peter pan homolog (Drosophila)
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
RAB30 RAB30, member RAS oncogene family
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RIBC2 RIB43A domain with coiled-coils 2
RIPPLY3 ripply transcriptional repressor 3
RPAP1 RNA polymerase II associated protein 1
RPGRIP1L RPGRIP1-like
SCAI suppressor of cancer cell invasion
SCD5 stearoyl-CoA desaturase 5
SCML2 sex comb on midleg-like 2 (Drosophila)
SH2D4A SH2 domain containing 4A
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLN sarcolipin
SNORA21 small nucleolar RNA, H/ACA box 21
SREK1IP1 SREK1-interacting protein 1
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TESK1 testis-specific kinase 1
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TLN1 talin 1
TMEM183A transmembrane protein 183A
TMEM242 transmembrane protein 242
TWISTNB TWIST neighbor
USB1 U6 snRNA biogenesis 1
USP19 ubiquitin specific peptidase 19
VGF VGF nerve growth factor inducible
ZBED1 zinc finger, BED-type containing 1
ZNF586 zinc finger protein 586
ZNF639 zinc finger protein 639
ZNF692 zinc finger protein 692
ZNF696 zinc finger protein 696
ZNF778 zinc finger protein 778
ZXDC ZXD family zinc finger C