suloctidil-6675 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the suloctidil-6675 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ADAM22 ADAM metallopeptidase domain 22
ADCK2 aarF domain containing kinase 2
ADGRB2 adhesion G protein-coupled receptor B2
ARC activity-regulated cytoskeleton-associated protein
ATF3 activating transcription factor 3
CCL19 chemokine (C-C motif) ligand 19
CCL20 chemokine (C-C motif) ligand 20
CCNO cyclin O
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CLCN6 chloride channel, voltage-sensitive 6
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL3 chemokine (C-X-C motif) ligand 3
CXCL8 chemokine (C-X-C motif) ligand 8
DBF4B DBF4 zinc finger B
DCC DCC netrin 1 receptor
DCLK2 doublecortin-like kinase 2
DDIT3 DNA-damage-inducible transcript 3
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DMP1 dentin matrix acidic phosphoprotein 1
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DUSP1 dual specificity phosphatase 1
EFNB3 ephrin-B3
EGR1 early growth response 1
FABP3 fatty acid binding protein 3, muscle and heart
FLJ11292
FLT3LG fms-related tyrosine kinase 3 ligand
FOS FBJ murine osteosarcoma viral oncogene homolog
GADD45B growth arrest and DNA-damage-inducible, beta
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMOX1 heme oxygenase 1
HOXC5 homeobox C5
ICAM1 intercellular adhesion molecule 1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IFNB1 interferon, beta 1, fibroblast
IL37 interleukin 37
IL6 interleukin 6
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
JUN jun proto-oncogene
JUNB jun B proto-oncogene
KLF13 Kruppel-like factor 13
KRT17 keratin 17, type I
KRT34 keratin 34, type I
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LINC00652 long intergenic non-protein coding RNA 652
LOC100287387 uncharacterized LOC100287387
LRRK1 leucine-rich repeat kinase 1
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MPO myeloperoxidase
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1M metallothionein 1M
MT1X metallothionein 1X
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
NEU3 sialidase 3 (membrane sialidase)
NOX1 NADPH oxidase 1
NPR1 natriuretic peptide receptor 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
OASL 2'-5'-oligoadenylate synthetase-like
PCDHGA11 protocadherin gamma subfamily A, 11
PDE4B phosphodiesterase 4B, cAMP-specific
PIGR polymeric immunoglobulin receptor
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
PTPRR protein tyrosine phosphatase, receptor type, R
RABEP2 rabaptin, RAB GTPase binding effector protein 2
RAD50 RAD50 homolog (S. cerevisiae)
RIC3 RIC3 acetylcholine receptor chaperone
RND1 Rho family GTPase 1
SARM1 sterile alpha and TIR motif containing 1
SEC24D SEC24 family member D
SLC22A6 solute carrier family 22 (organic anion transporter), member 6
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SPATA6L spermatogenesis associated 6-like
TBX2 T-box 2
TGFB2 transforming growth factor, beta 2
THSD7A thrombospondin, type I, domain containing 7A
TLX2 T-cell leukemia homeobox 2
TMPRSS4 transmembrane protease, serine 4
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
ZC3HAV1 zinc finger CCCH-type, antiviral 1
ZFP36 ZFP36 ring finger protein
ZNF165 zinc finger protein 165

decreased expression

Symbol Name
AGO4 argonaute RISC catalytic component 4
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANXA2P1 annexin A2 pseudogene 1
AOC2 amine oxidase, copper containing 2 (retina-specific)
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ATAD5 ATPase family, AAA domain containing 5
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
C11ORF30 chromosome 11 open reading frame 30
C11ORF63 chromosome 11 open reading frame 63
C14ORF93 chromosome 14 open reading frame 93
C1ORF56 chromosome 1 open reading frame 56
C5ORF42 chromosome 5 open reading frame 42
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
COLGALT2 collagen beta(1-O)galactosyltransferase 2
COQ4 coenzyme Q4
CST1 cystatin SN
DENND4A DENN/MADD domain containing 4A
DUSP8 dual specificity phosphatase 8
EDIL3 EGF-like repeats and discoidin I-like domains 3
ERN2 endoplasmic reticulum to nucleus signaling 2
ETNK2 ethanolamine kinase 2
FAM184A family with sequence similarity 184, member A
FKBP1B FK506 binding protein 1B, 12.6 kDa
FMO4 flavin containing monooxygenase 4
FOXN2 forkhead box N2
FRS3 fibroblast growth factor receptor substrate 3
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GRAMD1C GRAM domain containing 1C
HIST2H2AA3 histone cluster 2, H2aa3
HSF2BP heat shock transcription factor 2 binding protein
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
INO80D INO80 complex subunit D
ITK IL2-inducible T-cell kinase
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
KLC2 kinesin light chain 2
KRT37 keratin 37, type I
KRT75 keratin 75, type II
LAMC3 laminin, gamma 3
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LOC257152 uncharacterized LOC257152
LRRC16A leucine rich repeat containing 16A
LY6G6C lymphocyte antigen 6 complex, locus G6C
LYPLA2P1 lysophospholipase II pseudogene 1
MCC mutated in colorectal cancers
MCTP2 multiple C2 domains, transmembrane 2
MDFI MyoD family inhibitor
MEGF8 multiple EGF-like-domains 8
MFSD6 major facilitator superfamily domain containing 6
MOCS3 molybdenum cofactor synthesis 3
MRPL52 mitochondrial ribosomal protein L52
MTRF1 mitochondrial translational release factor 1
MTSS1L metastasis suppressor 1-like
MXD3 MAX dimerization protein 3
MYO1F myosin IF
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
NME5 NME/NM23 family member 5
NOD1 nucleotide-binding oligomerization domain containing 1
NPIPB15 nuclear pore complex interacting protein family, member B15
NPY1R neuropeptide Y receptor Y1
OSMR oncostatin M receptor
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PROL1 proline rich, lacrimal 1
PRSS22 protease, serine, 22
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RECQL4 RecQ protein-like 4
RIBC2 RIB43A domain with coiled-coils 2
ROM1 retinal outer segment membrane protein 1
RPH3A rabphilin 3A
RRAGB Ras-related GTP binding B
SARS2 seryl-tRNA synthetase 2, mitochondrial
SAYSD1 SAYSVFN motif domain containing 1
SCML2 sex comb on midleg-like 2 (Drosophila)
SCN1B sodium channel, voltage gated, type I beta subunit
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
SUOX sulfite oxidase
TEX40 testis expressed 40
TGFBI transforming growth factor, beta-induced, 68kDa
THBS3 thrombospondin 3
THRAP3 thyroid hormone receptor associated protein 3
TLR2 toll-like receptor 2
TM6SF1 transmembrane 6 superfamily member 1
TMEM120B transmembrane protein 120B
TMEM121 transmembrane protein 121
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
USP19 ubiquitin specific peptidase 19
VN1R1 vomeronasal 1 receptor 1
ZNF141 zinc finger protein 141
ZNF219 zinc finger protein 219
ZNF253 zinc finger protein 253
ZNF480 zinc finger protein 480
ZNF76 zinc finger protein 76