sulpiride-1887 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the sulpiride-1887 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4
ACAN aggrecan
ACSS3 acyl-CoA synthetase short-chain family member 3
ADAP1 ArfGAP with dual PH domains 1
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
ANKRD12 ankyrin repeat domain 12
AP1S2 adaptor-related protein complex 1, sigma 2 subunit
ARID4A AT rich interactive domain 4A (RBP1-like)
ATAD2B ATPase family, AAA domain containing 2B
ATG4B autophagy related 4B, cysteine peptidase
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1
AXIN1 axin 1
BCLAF1 BCL2-associated transcription factor 1
BTN3A1 butyrophilin, subfamily 3, member A1
C2CD2L C2CD2-like
CASP1 caspase 1, apoptosis-related cysteine peptidase
CD53 CD53 molecule
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CES3 carboxylesterase 3
CNOT8 CCR4-NOT transcription complex, subunit 8
CNTFR ciliary neurotrophic factor receptor
CRCP CGRP receptor component
CSNK1G2 casein kinase 1, gamma 2
CST4 cystatin S
CUL4A cullin 4A
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DGCR2 DiGeorge syndrome critical region gene 2
DUSP6 dual specificity phosphatase 6
EFNB3 ephrin-B3
EPOR erythropoietin receptor
FOSL2 FOS-like antigen 2
FOXO1 forkhead box O1
FSCN1 fascin actin-bundling protein 1
FSCN3 fascin actin-bundling protein 3, testicular
FXR2 fragile X mental retardation, autosomal homolog 2
GLIPR1 GLI pathogenesis-related 1
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GOLGA4 golgin A4
GRK6 G protein-coupled receptor kinase 6
HFE hemochromatosis
HIRIP3 HIRA interacting protein 3
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
ITPKC inositol-trisphosphate 3-kinase C
KCTD14 potassium channel tetramerization domain containing 14
LMF1 lipase maturation factor 1
MED7 mediator complex subunit 7
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MVB12B multivesicular body subunit 12B
NADK NAD kinase
NBL1 neuroblastoma 1, DAN family BMP antagonist
NCKAP1 NCK-associated protein 1
NPR3 natriuretic peptide receptor 3
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4
NUMB numb homolog (Drosophila)
OBSL1 obscurin-like 1
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PLAGL1 pleiomorphic adenoma gene-like 1
PPDPF pancreatic progenitor cell differentiation and proliferation factor
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4
PRDM14 PR domain containing 14
PTGDS prostaglandin D2 synthase 21kDa (brain)
RANBP3 RAN binding protein 3
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RB1 retinoblastoma 1
RECQL5 RecQ protein-like 5
RNF167 ring finger protein 167
RPL14 ribosomal protein L14
RPL7 ribosomal protein L7
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
RUSC2 RUN and SH3 domain containing 2
SCARA3 scavenger receptor class A, member 3
SLC22A18 solute carrier family 22, member 18
SLMO2 slowmo homolog 2 (Drosophila)
SMC2 structural maintenance of chromosomes 2
SMC5 structural maintenance of chromosomes 5
SP3 Sp3 transcription factor
SPN sialophorin
SPRR1A small proline-rich protein 1A
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3
TCF3 transcription factor 3
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
THADA thyroid adenoma associated
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TNK2 tyrosine kinase, non-receptor, 2
TOB2 transducer of ERBB2, 2
TPST2 tyrosylprotein sulfotransferase 2
TPT1 tumor protein, translationally-controlled 1
TRHDE thyrotropin-releasing hormone degrading enzyme
TSKU tsukushi, small leucine rich proteoglycan
TXNRD2 thioredoxin reductase 2
URI1 URI1, prefoldin-like chaperone
WWP2 WW domain containing E3 ubiquitin protein ligase 2
ZC3H7B zinc finger CCCH-type containing 7B
ZFP36 ZFP36 ring finger protein
ZNF652 zinc finger protein 652
ZNF721 zinc finger protein 721

decreased expression

Symbol Name
ACTG2 actin, gamma 2, smooth muscle, enteric
AIDA axin interactor, dorsalization associated
AKTIP AKT interacting protein
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
AP1B1 adaptor-related protein complex 1, beta 1 subunit
APIP APAF1 interacting protein
ARFIP2 ADP-ribosylation factor interacting protein 2
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARMC6 armadillo repeat containing 6
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
ATAT1 alpha tubulin acetyltransferase 1
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
CDC45 cell division cycle 45
CFD complement factor D (adipsin)
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CLK3 CDC-like kinase 3
CTDNEP1 CTD nuclear envelope phosphatase 1
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
DCLRE1B DNA cross-link repair 1B
DDIT3 DNA-damage-inducible transcript 3
DEPDC1 DEP domain containing 1
DESI1 desumoylating isopeptidase 1
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha)
ECHDC1 ethylmalonyl-CoA decarboxylase 1
ECI1 enoyl-CoA delta isomerase 1
EDC4 enhancer of mRNA decapping 4
EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa
ELAVL2 ELAV like neuron-specific RNA binding protein 2
ERCC2 excision repair cross-complementation group 2
EXOC5 exocyst complex component 5
FKBPL FK506 binding protein like
GALR3 galanin receptor 3
GSTZ1 glutathione S-transferase zeta 1
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa
GTPBP6 GTP binding protein 6 (putative)
HIST3H2A histone cluster 3, H2a
HNRNPF heterogeneous nuclear ribonucleoprotein F
HOOK2 hook microtubule-tethering protein 2
HSPA4L heat shock 70kDa protein 4-like
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
IFI6 interferon, alpha-inducible protein 6
ITFG1 integrin alpha FG-GAP repeat containing 1
KAT2A K(lysine) acetyltransferase 2A
KCTD20 potassium channel tetramerization domain containing 20
KIF20B kinesin family member 20B
LIPT1 lipoyltransferase 1
MFSD12 major facilitator superfamily domain containing 12
MRPL12 mitochondrial ribosomal protein L12
MRPL48 mitochondrial ribosomal protein L48
MT1HL1 metallothionein 1H-like 1
MUTYH mutY homolog
NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa
NRBF2 nuclear receptor binding factor 2
NVL nuclear VCP-like
OSGEP O-sialoglycoprotein endopeptidase
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
OXA1L oxidase (cytochrome c) assembly 1-like
PAAF1 proteasomal ATPase-associated factor 1
PHKA1 phosphorylase kinase, alpha 1 (muscle)
PLEKHO2 pleckstrin homology domain containing, family O member 2
PMPCA peptidase (mitochondrial processing) alpha
PMVK phosphomevalonate kinase
PRAME preferentially expressed antigen in melanoma
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
PSAT1 phosphoserine aminotransferase 1
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
PYCRL pyrroline-5-carboxylate reductase-like
RAB36 RAB36, member RAS oncogene family
RIC8A RIC8 guanine nucleotide exchange factor A
RPL11 ribosomal protein L11
RRP1 ribosomal RNA processing 1
RUVBL1 RuvB-like AAA ATPase 1
SERF2 small EDRK-rich factor 2
SGPP1 sphingosine-1-phosphate phosphatase 1
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SNX5 sorting nexin 5
SPDL1 spindle apparatus coiled-coil protein 1
STK16 serine/threonine kinase 16
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
TFPT TCF3 (E2A) fusion partner (in childhood Leukemia)
TMEM230 transmembrane protein 230
TRAPPC6A trafficking protein particle complex 6A
TSPAN32 tetraspanin 32
TULP4 tubby like protein 4
TWSG1 twisted gastrulation BMP signaling modulator 1
WWC2 WW and C2 domain containing 2
XPC xeroderma pigmentosum, complementation group C
ZMYM3 zinc finger, MYM-type 3
ZNF263 zinc finger protein 263
ZNF281 zinc finger protein 281
ZNF32 zinc finger protein 32
ZNF322P1 zinc finger protein 322 pseudogene 1
ZNF394 zinc finger protein 394