sulpiride-1967 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the sulpiride-1967 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ACAA2 acetyl-CoA acyltransferase 2
AHNAK AHNAK nucleoprotein
APOC1 apolipoprotein C-I
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
ARID5A AT rich interactive domain 5A (MRF1-like)
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa
ATP9B ATPase, class II, type 9B
BMP7 bone morphogenetic protein 7
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
CALML4 calmodulin-like 4
CAPN3 calpain 3, (p94)
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CD24 CD24 molecule
CDC37 cell division cycle 37
CDK9 cyclin-dependent kinase 9
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
CDV3 CDV3 homolog (mouse)
CETN1 centrin, EF-hand protein, 1
CHD1L chromodomain helicase DNA binding protein 1-like
CYLD cylindromatosis (turban tumor syndrome)
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DGCR8 DGCR8 microprocessor complex subunit
DIXDC1 DIX domain containing 1
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7
DUSP2 dual specificity phosphatase 2
DXO decapping exoribonuclease
DYM dymeclin
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
EFCAB11 EF-hand calcium binding domain 11
EID1 EP300 interacting inhibitor of differentiation 1
ELOVL6 ELOVL fatty acid elongase 6
FANCF Fanconi anemia, complementation group F
FH fumarate hydratase
FLI1 Fli-1 proto-oncogene, ETS transcription factor
GANAB glucosidase, alpha; neutral AB
GFOD2 glucose-fructose oxidoreductase domain containing 2
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa
HLA-E major histocompatibility complex, class I, E
HP1BP3 heterochromatin protein 1, binding protein 3
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LPP LIM domain containing preferred translocation partner in lipoma
MAGT1 magnesium transporter 1
MED14 mediator complex subunit 14
MED7 mediator complex subunit 7
METAP2 methionyl aminopeptidase 2
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MON1B MON1 secretory trafficking family member B
MT1F metallothionein 1F
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NBR1 neighbor of BRCA1 gene 1
NFX1 nuclear transcription factor, X-box binding 1
NR6A1 nuclear receptor subfamily 6, group A, member 1
OR2H2 olfactory receptor, family 2, subfamily H, member 2
ORAI2 ORAI calcium release-activated calcium modulator 2
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PCDHGB5 protocadherin gamma subfamily B, 5
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PLEC plectin
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
POR P450 (cytochrome) oxidoreductase
POT1 protection of telomeres 1
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PTP4A1 protein tyrosine phosphatase type IVA, member 1
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RAB2A RAB2A, member RAS oncogene family
RABIF RAB interacting factor
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1
RGS1 regulator of G-protein signaling 1
RPE ribulose-5-phosphate-3-epimerase
SEC23IP SEC23 interacting protein
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SIRPA signal-regulatory protein alpha
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SLC52A2 solute carrier family 52 (riboflavin transporter), member 2
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SUGP1 SURP and G patch domain containing 1
SYMPK symplekin
TCAF1 TRPM8 channel-associated factor 1
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TMED9 transmembrane emp24 protein transport domain containing 9
TPRA1 transmembrane protein, adipocyte asscociated 1
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae)
WAS Wiskott-Aldrich syndrome
WDR1 WD repeat domain 1
WDR44 WD repeat domain 44
WSB2 WD repeat and SOCS box containing 2
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ABHD11 abhydrolase domain containing 11
AHR aryl hydrocarbon receptor
ALPK1 alpha-kinase 1
APEX2 APEX nuclease (apurinic/apyrimidinic endonuclease) 2
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
ASB13 ankyrin repeat and SOCS box containing 13
ATAD2B ATPase family, AAA domain containing 2B
BAK1 BCL2-antagonist/killer 1
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BATF3 basic leucine zipper transcription factor, ATF-like 3
BTNL3 butyrophilin-like 3
C14ORF159 chromosome 14 open reading frame 159
C1ORF109 chromosome 1 open reading frame 109
CAPN1 calpain 1, (mu/I) large subunit
CARHSP1 calcium regulated heat stable protein 1, 24kDa
CCDC6 coiled-coil domain containing 6
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEND1 cell cycle exit and neuronal differentiation 1
CFL1 cofilin 1 (non-muscle)
CLDN15 claudin 15
CLEC16A C-type lectin domain family 16, member A
CLK1 CDC-like kinase 1
CORO7 coronin 7
CPA2 carboxypeptidase A2 (pancreatic)
DCUN1D2 DCN1, defective in cullin neddylation 1, domain containing 2
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DOK2 docking protein 2, 56kDa
DUSP5 dual specificity phosphatase 5
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
EDEM2 ER degradation enhancer, mannosidase alpha-like 2
ERF Ets2 repressor factor
EXD2 exonuclease 3'-5' domain containing 2
FAM160B2 family with sequence similarity 160, member B2
FAM222B family with sequence similarity 222, member B
FAM53C family with sequence similarity 53, member C
FGL2 fibrinogen-like 2
FPGS folylpolyglutamate synthase
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GMIP GEM interacting protein
GMPPB GDP-mannose pyrophosphorylase B
GUSBP3 glucuronidase, beta pseudogene 3
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIRA histone cell cycle regulator
HK1 hexokinase 1
HRSP12 heat-responsive protein 12
HS1BP3 HCLS1 binding protein 3
IFT20 intraflagellar transport 20
IFT52 intraflagellar transport 52
INO80D INO80 complex subunit D
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITGA10 integrin, alpha 10
KLRG1 killer cell lectin-like receptor subfamily G, member 1
KPNA4 karyopherin alpha 4 (importin alpha 3)
LHFPL2 lipoma HMGIC fusion partner-like 2
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LONRF3 LON peptidase N-terminal domain and ring finger 3
LRRK1 leucine-rich repeat kinase 1
LSP1 lymphocyte-specific protein 1
MAPKBP1 mitogen-activated protein kinase binding protein 1
MITF microphthalmia-associated transcription factor
NEK11 NIMA-related kinase 11
PADI1 peptidyl arginine deiminase, type I
PHACTR4 phosphatase and actin regulator 4
PMM1 phosphomannomutase 1
PNRC1 proline-rich nuclear receptor coactivator 1
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
RIC8A RIC8 guanine nucleotide exchange factor A
SCN10A sodium channel, voltage gated, type X alpha subunit
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SETX senataxin
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC25A38 solute carrier family 25, member 38
SOX12 SRY (sex determining region Y)-box 12
SP140L SP140 nuclear body protein-like
SS18L1 synovial sarcoma translocation gene on chromosome 18-like 1
STAC SH3 and cysteine rich domain
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
TERT telomerase reverse transcriptase
TESK2 testis-specific kinase 2
TMEM104 transmembrane protein 104
TMEM110 transmembrane protein 110
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TUBA3C tubulin, alpha 3c
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UBE2O ubiquitin-conjugating enzyme E2O
UNG uracil-DNA glycosylase
USB1 U6 snRNA biogenesis 1
UTP11L UTP11-like, U3 small nucleolar ribonucleoprotein (yeast)
VASP vasodilator-stimulated phosphoprotein
XPC xeroderma pigmentosum, complementation group C
ZC3H12A zinc finger CCCH-type containing 12A
ZDHHC18 zinc finger, DHHC-type containing 18
ZNF14 zinc finger protein 14
ZNF408 zinc finger protein 408
ZNF721 zinc finger protein 721
ZNF768 zinc finger protein 768