sulpiride-4389 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the sulpiride-4389 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACACB acetyl-CoA carboxylase beta
ACAN aggrecan
ALDOB aldolase B, fructose-bisphosphate
AMACR alpha-methylacyl-CoA racemase
ANO1 anoctamin 1, calcium activated chloride channel
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BCL2 B-cell CLL/lymphoma 2
BMP6 bone morphogenetic protein 6
BTNL3 butyrophilin-like 3
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CALCR calcitonin receptor
CALD1 caldesmon 1
CD83 CD83 molecule
CDK13 cyclin-dependent kinase 13
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CEP112 centrosomal protein 112kDa
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CLDN8 claudin 8
CLEC4M C-type lectin domain family 4, member M
CNN1 calponin 1, basic, smooth muscle
COL8A2 collagen, type VIII, alpha 2
CRLF2 cytokine receptor-like factor 2
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CXORF21 chromosome X open reading frame 21
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DAPK2 death-associated protein kinase 2
DCBLD2 discoidin, CUB and LCCL domain containing 2
DDO D-aspartate oxidase
DYM dymeclin
ELL2 elongation factor, RNA polymerase II, 2
EMX1 empty spiracles homeobox 1
EXPH5 exophilin 5
EYA3 EYA transcriptional coactivator and phosphatase 3
F13A1 coagulation factor XIII, A1 polypeptide
FBN1 fibrillin 1
FGF18 fibroblast growth factor 18
FGF22 fibroblast growth factor 22
FPR3 formyl peptide receptor 3
GM2A GM2 ganglioside activator
GRM1 glutamate receptor, metabotropic 1
HCRT hypocretin (orexin) neuropeptide precursor
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
IGFBP7 insulin-like growth factor binding protein 7
IL12B interleukin 12B
IL24 interleukin 24
ITGB6 integrin, beta 6
KRT9 keratin 9, type I
LAMC3 laminin, gamma 3
LPP LIM domain containing preferred translocation partner in lipoma
LRMP lymphoid-restricted membrane protein
LSP1 lymphocyte-specific protein 1
MAL mal, T-cell differentiation protein
MET MET proto-oncogene, receptor tyrosine kinase
MMP3 matrix metallopeptidase 3
NCF4 neutrophil cytosolic factor 4, 40kDa
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
NEUROG2 neurogenin 2
OLFM1 olfactomedin 1
OSBP2 oxysterol binding protein 2
PALM paralemmin
PDLIM5 PDZ and LIM domain 5
PDPK1 3-phosphoinositide dependent protein kinase 1
PIP prolactin-induced protein
PKNOX1 PBX/knotted 1 homeobox 1
PLCE1 phospholipase C, epsilon 1
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PMFBP1 polyamine modulated factor 1 binding protein 1
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PSG1 pregnancy specific beta-1-glycoprotein 1
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTRF polymerase I and transcript release factor
RAB11B RAB11B, member RAS oncogene family
RAB14 RAB14, member RAS oncogene family
RAB6B RAB6B, member RAS oncogene family
RAI2 retinoic acid induced 2
RASSF4 Ras association (RalGDS/AF-6) domain family member 4
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RNF5 ring finger protein 5, E3 ubiquitin protein ligase
RUNX1 runt-related transcription factor 1
SAYSD1 SAYSVFN motif domain containing 1
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SIRPA signal-regulatory protein alpha
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SPP1 secreted phosphoprotein 1
SPPL2B signal peptide peptidase like 2B
TCF12 transcription factor 12
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TEF thyrotrophic embryonic factor
TM4SF4 transmembrane 4 L six family member 4
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TNS1 tensin 1
TRIM49 tripartite motif containing 49
TUBA3C tubulin, alpha 3c
ZRSR1 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1

decreased expression

Symbol Name
ACTL8 actin-like 8
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADCY6 adenylate cyclase 6
ADM adrenomedullin
AFAP1 actin filament associated protein 1
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
AHDC1 AT hook, DNA binding motif, containing 1
AMT aminomethyltransferase
APLP1 amyloid beta (A4) precursor-like protein 1
ATAT1 alpha tubulin acetyltransferase 1
ATG9A autophagy related 9A
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BHLHE41 basic helix-loop-helix family, member e41
BTF3P11 basic transcription factor 3 pseudogene 11
C10ORF95 chromosome 10 open reading frame 95
C11ORF30 chromosome 11 open reading frame 30
C1ORF54 chromosome 1 open reading frame 54
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C7ORF43 chromosome 7 open reading frame 43
CA5BP1 carbonic anhydrase VB pseudogene 1
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CD3D CD3d molecule, delta (CD3-TCR complex)
CES3 carboxylesterase 3
CLDN9 claudin 9
DNAL4 dynein, axonemal, light chain 4
DPY19L1P1 DPY19L1 pseudogene 1
ELP6 elongator acetyltransferase complex subunit 6
ERN2 endoplasmic reticulum to nucleus signaling 2
F2R coagulation factor II (thrombin) receptor
FBXO2 F-box protein 2
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GUSBP3 glucuronidase, beta pseudogene 3
HDAC7 histone deacetylase 7
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIRA histone cell cycle regulator
HIST1H4A histone cluster 1, H4a
HIST1H4C histone cluster 1, H4c
HMOX1 heme oxygenase 1
HOOK1 hook microtubule-tethering protein 1
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IL22 interleukin 22
INO80D INO80 complex subunit D
IRF9 interferon regulatory factor 9
KCNIP1 Kv channel interacting protein 1
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
LIME1 Lck interacting transmembrane adaptor 1
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LY6G6C lymphocyte antigen 6 complex, locus G6C
MED15 mediator complex subunit 15
METTL8 methyltransferase like 8
MRPL41 mitochondrial ribosomal protein L41
MTMR6 myotubularin related protein 6
MUC3A mucin 3A, cell surface associated
NRSN2 neurensin 2
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
PCDHGA10 protocadherin gamma subfamily A, 10
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PEX26 peroxisomal biogenesis factor 26
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLAC1 placenta-specific 1
PLD3 phospholipase D family, member 3
PLEKHO1 pleckstrin homology domain containing, family O member 1
PLXNB3 plexin B3
POLM polymerase (DNA directed), mu
POMT2 protein-O-mannosyltransferase 2
POU4F2 POU class 4 homeobox 2
PP14571 uncharacterized LOC100130449
RGS20 regulator of G-protein signaling 20
RNF208 ring finger protein 208
RORC RAR-related orphan receptor C
RPL10L ribosomal protein L10-like
RUSC2 RUN and SH3 domain containing 2
SH2B3 SH2B adaptor protein 3
SIGLEC15 sialic acid binding Ig-like lectin 15
SIX1 SIX homeobox 1
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLMO1 slowmo homolog 1 (Drosophila)
SNTA1 syntrophin, alpha 1
SPRR2B small proline-rich protein 2B
STAG3 stromal antigen 3
STARD3 StAR-related lipid transfer (START) domain containing 3
STRA6 stimulated by retinoic acid 6
TPSG1 tryptase gamma 1
TRAIP TRAF interacting protein
TRIM21 tripartite motif containing 21
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TTC30A tetratricopeptide repeat domain 30A
UBXN6 UBX domain protein 6
USP36 ubiquitin specific peptidase 36
VASH2 vasohibin 2
WDR4 WD repeat domain 4
XYLT2 xylosyltransferase II
ZBTB22 zinc finger and BTB domain containing 22
ZNF573 zinc finger protein 573
ZSCAN2 zinc finger and SCAN domain containing 2
ZW10 zw10 kinetochore protein