sumo1 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description small ubiquitin-like modifier 1|This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last four amino acids of the carboxy-terminus have been cleaved off. Several pseudogenes have been reported for this gene. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 7341)
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Genes

83 genes co-occuring with the biological term sumo1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ARNT aryl hydrocarbon receptor nuclear translocator
ATXN3 ataxin 3
BACE1 beta-site APP-cleaving enzyme 1
BRCA1 breast cancer 1, early onset
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CENPC centromere protein C
CREB1 cAMP responsive element binding protein 1
CRH corticotropin releasing hormone
CYBB cytochrome b-245, beta polypeptide
DLX3 distal-less homeobox 3
DNM1 dynamin 1
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DPP9 dipeptidyl-peptidase 9
EGR1 early growth response 1
ESR2 estrogen receptor 2 (ER beta)
FOS FBJ murine osteosarcoma viral oncogene homolog
HDGF hepatoma-derived growth factor
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2
HIPK2 homeodomain interacting protein kinase 2
HMGN2 high mobility group nucleosomal binding domain 2
HSF1 heat shock transcription factor 1
IFIH1 interferon induced with helicase C domain 1
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
JUN jun proto-oncogene
MAPK1 mitogen-activated protein kinase 1
MAPT microtubule-associated protein tau
MBD1 methyl-CpG binding domain protein 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MX1 MX dynamin-like GTPase 1
NCOA2 nuclear receptor coactivator 2
NEDD8 neural precursor cell expressed, developmentally down-regulated 8
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NKX2-5 NK2 homeobox 5
NOS1 nitric oxide synthase 1 (neuronal)
NR3C2 nuclear receptor subfamily 3, group C, member 2
NR5A2 nuclear receptor subfamily 5, group A, member 2
NUB1 negative regulator of ubiquitin-like proteins 1
NUMA1 nuclear mitotic apparatus protein 1
PDC phosducin
PGR progesterone receptor
PIAS2 protein inhibitor of activated STAT, 2
PIAS4 protein inhibitor of activated STAT, 4
PLAGL1 pleiomorphic adenoma gene-like 1
PML promyelocytic leukemia
POU5F1 POU class 5 homeobox 1
PTBP2 polypyrimidine tract binding protein 2
PTEN phosphatase and tensin homolog
RANBP2 RAN binding protein 2
RANGAP1 Ran GTPase activating protein 1
RARA retinoic acid receptor, alpha
RCOR1 REST corepressor 1
RNF8 ring finger protein 8, E3 ubiquitin protein ligase
RORA RAR-related orphan receptor A
RPS3 ribosomal protein S3
SAE1 SUMO1 activating enzyme subunit 1
SAFB scaffold attachment factor B
SALL1 spalt-like transcription factor 1
SENP1 SUMO1/sentrin specific peptidase 1
SENP5 SUMO1/sentrin specific peptidase 5
SENP6 SUMO1/sentrin specific peptidase 6
SENP7 SUMO1/sentrin specific peptidase 7
SMAD3 SMAD family member 3
SMAD4 SMAD family member 4
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOX3 SRY (sex determining region Y)-box 3
SRF serum response factor (c-fos serum response element-binding transcription factor)
STAT1 signal transducer and activator of transcription 1, 91kDa
SUMO1 small ubiquitin-like modifier 1
SUMO2 small ubiquitin-like modifier 2
SUMO3 small ubiquitin-like modifier 3
TBX22 T-box 22
TDG thymine-DNA glycosylase
TOP1 topoisomerase (DNA) I
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TP53 tumor protein p53
TP63 tumor protein p63
UBE2I ubiquitin-conjugating enzyme E2I
ZBTB16 zinc finger and BTB domain containing 16
ZHX1 zinc fingers and homeoboxes 1
ZMYM2 zinc finger, MYM-type 2
ZNF146 zinc finger protein 146