sunitinib Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A pyrrole that has formula C22H27FN4O2. (Chemical Entities of Biological Interest Ontology, CHEBI_38940)
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Genes

38 genes co-occuring with the biological term sunitinib in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
AHR aryl hydrocarbon receptor
AKT1 v-akt murine thymoma viral oncogene homolog 1
ANGPT2 angiopoietin 2
BSG basigin (Ok blood group)
CSF1R colony stimulating factor 1 receptor
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR4 chemokine (C-X-C motif) receptor 4
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP3A cytochrome P450, family 3, subfamily A
DEC1 deleted in esophageal cancer 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPO erythropoietin
EPOR erythropoietin receptor
ERBB2 erb-b2 receptor tyrosine kinase 2
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
KDR kinase insert domain receptor
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KRAS Kirsten rat sarcoma viral oncogene homolog
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MTOR mechanistic target of rapamycin (serine/threonine kinase)
NOS3 nitric oxide synthase 3 (endothelial cell)
NPPB natriuretic peptide B
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PRKX protein kinase, X-linked
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TIMP2 TIMP metallopeptidase inhibitor 2
TP53 tumor protein p53
TSC1 tuberous sclerosis 1
TSC2 tuberous sclerosis 2
TTBK2 tau tubulin kinase 2
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
VEGFA vascular endothelial growth factor A