suppressor Gene Set

Dataset Phosphosite Textmining Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

278 proteins co-occuring with the biological term suppressor in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset.

Symbol Name
AATF apoptosis antagonizing transcription factor
ACACA acetyl-CoA carboxylase alpha
ADD1 adducin 1 (alpha)
ADD3 adducin 3 (gamma)
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AKAP12 A kinase (PRKA) anchor protein 12
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT1S1 AKT1 substrate 1 (proline-rich)
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
APC adenomatous polyposis coli
AR androgen receptor
ARAF A-Raf proto-oncogene, serine/threonine kinase
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
ARID4A AT rich interactive domain 4A (RBP1-like)
ATF2 activating transcription factor 2
ATM ATM serine/threonine kinase
ATR ATR serine/threonine kinase
AURKA aurora kinase A
AURKB aurora kinase B
BAD BCL2-associated agonist of cell death
BANP BTG3 associated nuclear protein
BARD1 BRCA1 associated RING domain 1
BCAR1 breast cancer anti-estrogen resistance 1
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BECN1 beclin 1, autophagy related
BMI1 BMI1 proto-oncogene, polycomb ring finger
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BRIP1 BRCA1 interacting protein C-terminal helicase 1
BRSK1 BR serine/threonine kinase 1
BTG1 B-cell translocation gene 1, anti-proliferative
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CARD9 caspase recruitment domain family, member 9
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCND1 cyclin D1
CDC25A cell division cycle 25A
CDC25C cell division cycle 25C
CDC73 cell division cycle 73
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDK1 cyclin-dependent kinase 1
CDK2 cyclin-dependent kinase 2
CDK2AP1 cyclin-dependent kinase 2 associated protein 1
CDK5 cyclin-dependent kinase 5
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CENPA centromere protein A
CFL1 cofilin 1 (non-muscle)
CHEK1 checkpoint kinase 1
CHEK2 checkpoint kinase 2
CHUK conserved helix-loop-helix ubiquitous kinase
CLK2 CDC-like kinase 2
CREB1 cAMP responsive element binding protein 1
CREM cAMP responsive element modulator
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CSF1R colony stimulating factor 1 receptor
CSF3R colony stimulating factor 3 receptor (granulocyte)
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CUL5 cullin 5
CYLD cylindromatosis (turban tumor syndrome)
DAP death-associated protein
DAPK1 death-associated protein kinase 1
DBN1 drebrin 1
DLC1 DLC1 Rho GTPase activating protein
DLG1 discs, large homolog 1 (Drosophila)
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
E2F1 E2F transcription factor 1
EGFR epidermal growth factor receptor
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
EIF4E eukaryotic translation initiation factor 4E
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
ELK1 ELK1, member of ETS oncogene family
ENG endoglin
EPOR erythropoietin receptor
ERBB2 erb-b2 receptor tyrosine kinase 2
ERRFI1 ERBB receptor feedback inhibitor 1
ESR1 estrogen receptor 1
ETV1 ets variant 1
ETV6 ets variant 6
EXOSC9 exosome component 9
EZR ezrin
FADD Fas (TNFRSF6)-associated via death domain
FBXO31 F-box protein 31
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FES FES proto-oncogene, tyrosine kinase
FHIT fragile histidine triad
FLCN folliculin
FLT3 fms-related tyrosine kinase 3
FMR1 fragile X mental retardation 1
FOXO1 forkhead box O1
FOXO3 forkhead box O3
FOXO4 forkhead box O4
GHR growth hormone receptor
GRB10 growth factor receptor-bound protein 10
GRIA1 glutamate receptor, ionotropic, AMPA 1
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
GTF2A1 general transcription factor IIA, 1, 19/37kDa
H2AFX H2A histone family, member X
HIST1H3A histone cluster 1, H3a
HNRNPL heterogeneous nuclear ribonucleoprotein L
HSPB1 heat shock 27kDa protein 1
IFNGR1 interferon gamma receptor 1
IL6ST interleukin 6 signal transducer
INCA1 inhibitor of CDK, cyclin A1 interacting protein 1
ING1 inhibitor of growth family, member 1
INSR insulin receptor
IRS1 insulin receptor substrate 1
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
JAK1 Janus kinase 1
JAK2 Janus kinase 2
JUN jun proto-oncogene
JUNB jun B proto-oncogene
JUND jun D proto-oncogene
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1
KDR kinase insert domain receptor
KIF2C kinesin family member 2C
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLF5 Kruppel-like factor 5 (intestinal)
KSR1 kinase suppressor of ras 1
LATS1 large tumor suppressor kinase 1
LATS2 large tumor suppressor kinase 2
LCK LCK proto-oncogene, Src family tyrosine kinase
LEPR leptin receptor
LIMA1 LIM domain and actin binding 1
LIMK1 LIM domain kinase 1
LIMK2 LIM domain kinase 2
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LRP6 low density lipoprotein receptor-related protein 6
LYN LYN proto-oncogene, Src family tyrosine kinase
MAGEA11 melanoma antigen family A11
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K4 mitogen-activated protein kinase kinase 4
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK7 mitogen-activated protein kinase 7
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
MAPT microtubule-associated protein tau
MARK1 MAP/microtubule affinity-regulating kinase 1
MARK2 MAP/microtubule affinity-regulating kinase 2
MARS methionyl-tRNA synthetase
MCC mutated in colorectal cancers
MCL1 myeloid cell leukemia 1
MCM2 minichromosome maintenance complex component 2
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
MEN1 multiple endocrine neoplasia I
MET MET proto-oncogene, receptor tyrosine kinase
MFN2 mitofusin 2
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MKL1 megakaryoblastic leukemia (translocation) 1
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MXD1 MAX dimerization protein 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYL12B myosin, light chain 12B, regulatory
NCOA3 nuclear receptor coactivator 3
NDRG1 N-myc downstream regulated 1
NF1 neurofibromin 1
NF2 neurofibromin 2 (merlin)
NKX3-1 NK3 homeobox 1
NME1 NME/NM23 nucleoside diphosphate kinase 1
NME2 NME/NM23 nucleoside diphosphate kinase 2
NME3 NME/NM23 nucleoside diphosphate kinase 3
NOS3 nitric oxide synthase 3 (endothelial cell)
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NR5A1 nuclear receptor subfamily 5, group A, member 1
NUAK1 NUAK family, SNF1-like kinase, 1
OPRK1 opioid receptor, kappa 1
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAWR PRKC, apoptosis, WT1, regulator
PCGF6 polycomb group ring finger 6
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1
PDLIM2 PDZ and LIM domain 2 (mystique)
PDPK1 3-phosphoinositide dependent protein kinase 1
PGAM1 phosphoglycerate mutase 1 (brain)
PHF20 PHD finger protein 20
PHGDH phosphoglycerate dehydrogenase
PIAS1 protein inhibitor of activated STAT, 1
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLCG1 phospholipase C, gamma 1
PML promyelocytic leukemia
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKCD protein kinase C, delta
PRKCE protein kinase C, epsilon
PRKG2 protein kinase, cGMP-dependent, type II
PRLR prolactin receptor
PTEN phosphatase and tensin homolog
PTK2 protein tyrosine kinase 2
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PXN paxillin
RAD17 RAD17 homolog (S. pombe)
RAD52 RAD52 homolog (S. cerevisiae)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RALA v-ral simian leukemia viral oncogene homolog A (ras related)
RAP1A RAP1A, member of RAS oncogene family
RAP1GAP RAP1 GTPase activating protein
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RB1 retinoblastoma 1
RBBP8 retinoblastoma binding protein 8
RBL1 retinoblastoma-like 1
RBL2 retinoblastoma-like 2
RBM4 RNA binding motif protein 4
RBPJ recombination signal binding protein for immunoglobulin kappa J region
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RFWD2 ring finger and WD repeat domain 2, E3 ubiquitin protein ligase
RPA2 replication protein A2, 32kDa
RPS6 ribosomal protein S6
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RPTOR regulatory associated protein of MTOR, complex 1
RRAD Ras-related associated with diabetes
RUNX3 runt-related transcription factor 3
SAV1 salvador family WW domain containing protein 1
SCRIB scribbled planar cell polarity protein
SIAH1 siah E3 ubiquitin protein ligase 1
SIAH2 siah E3 ubiquitin protein ligase 2
SIKE1 suppressor of IKBKE 1
SIRT1 sirtuin 1
SMAD3 SMAD family member 3
SMAD4 SMAD family member 4
SNAI1 snail family zinc finger 1
SNCB synuclein, beta
SNRK SNF related kinase
SOCS3 suppressor of cytokine signaling 3
SPRY2 sprouty homolog 2 (Drosophila)
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SSB Sjogren syndrome antigen B (autoantigen La)
SSH1 slingshot protein phosphatase 1
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT2 signal transducer and activator of transcription 2, 113kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
STK11 serine/threonine kinase 11
STK3 serine/threonine kinase 3
STK38 serine/threonine kinase 38
STRADA STE20-related kinase adaptor alpha
SUFU suppressor of fused homolog (Drosophila)
SUGT1 SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)
SYK spleen tyrosine kinase
TAGLN2 transgelin 2
TCF3 transcription factor 3
TOP1 topoisomerase (DNA) I
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TP53 tumor protein p53
TP73 tumor protein p73
TRIP10 thyroid hormone receptor interactor 10
TSC1 tuberous sclerosis 1
TSC2 tuberous sclerosis 2
UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7
UIMC1 ubiquitin interaction motif containing 1
ULK3 unc-51 like kinase 3
USF1 upstream transcription factor 1
USP10 ubiquitin specific peptidase 10
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
WT1 Wilms tumor 1
WWC1 WW and C2 domain containing 1
WWOX WW domain containing oxidoreductase
YAP1 Yes-associated protein 1
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
ZBTB16 zinc finger and BTB domain containing 16