suprofen-3005 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the suprofen-3005 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADIRF adipogenesis regulatory factor
AGBL3 ATP/GTP binding protein-like 3
AKAP6 A kinase (PRKA) anchor protein 6
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
ANG angiogenin, ribonuclease, RNase A family, 5
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
AQP9 aquaporin 9
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARHGAP35 Rho GTPase activating protein 35
ARMC9 armadillo repeat containing 9
ARTN artemin
ATP10B ATPase, class V, type 10B
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BMP8B bone morphogenetic protein 8b
C2ORF27A chromosome 2 open reading frame 27A
C9ORF116 chromosome 9 open reading frame 116
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CAV2 caveolin 2
CCL24 chemokine (C-C motif) ligand 24
CD7 CD7 molecule
CD8B CD8b molecule
CDHR5 cadherin-related family member 5
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHGB chromogranin B
COL1A1 collagen, type I, alpha 1
CRAT carnitine O-acetyltransferase
CTRC chymotrypsin C (caldecrin)
CYFIP2 cytoplasmic FMR1 interacting protein 2
DCX doublecortin
DDAH2 dimethylarginine dimethylaminohydrolase 2
DGKI diacylglycerol kinase, iota
DSTYK dual serine/threonine and tyrosine protein kinase
DUSP4 dual specificity phosphatase 4
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
ERAP1 endoplasmic reticulum aminopeptidase 1
EXOG endo/exonuclease (5'-3'), endonuclease G-like
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
FN1 fibronectin 1
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GJA8 gap junction protein, alpha 8, 50kDa
HES1 hes family bHLH transcription factor 1
HIF3A hypoxia inducible factor 3, alpha subunit
HIST1H2BC histone cluster 1, H2bc
HOXB1 homeobox B1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
INF2 inverted formin, FH2 and WH2 domain containing
ITM2A integral membrane protein 2A
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
LAMP1 lysosomal-associated membrane protein 1
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
MDK midkine (neurite growth-promoting factor 2)
MECOM MDS1 and EVI1 complex locus
MED14 mediator complex subunit 14
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MYL10 myosin, light chain 10, regulatory
NEU3 sialidase 3 (membrane sialidase)
NOP16 NOP16 nucleolar protein
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OCM2 oncomodulin 2
OSBPL10 oxysterol binding protein-like 10
PACRG PARK2 co-regulated
PAIP2B poly(A) binding protein interacting protein 2B
PAX5 paired box 5
PBX2 pre-B-cell leukemia homeobox 2
PEG10 paternally expressed 10
POMT2 protein-O-mannosyltransferase 2
PPP1R3A protein phosphatase 1, regulatory subunit 3A
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PTGDR2 prostaglandin D2 receptor 2
PTGER3 prostaglandin E receptor 3 (subtype EP3)
RASAL1 RAS protein activator like 1 (GAP1 like)
RCVRN recoverin
S1PR2 sphingosine-1-phosphate receptor 2
SCAND2P SCAN domain containing 2 pseudogene
SCIN scinderin
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SGPL1 sphingosine-1-phosphate lyase 1
SHANK2 SH3 and multiple ankyrin repeat domains 2
SLC12A8 solute carrier family 12, member 8
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SNPH syntaphilin
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
STK3 serine/threonine kinase 3
TAAR3 trace amine associated receptor 3 (gene/pseudogene)
TGFBR3 transforming growth factor, beta receptor III
TKTL1 transketolase-like 1
TMEM63A transmembrane protein 63A
TMPRSS2 transmembrane protease, serine 2
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TRPC7 transient receptor potential cation channel, subfamily C, member 7
TUBA4B tubulin, alpha 4b
ZNF442 zinc finger protein 442

decreased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ADGB androglobin
ADGRE3 adhesion G protein-coupled receptor E3
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
ARMC6 armadillo repeat containing 6
ASGR2 asialoglycoprotein receptor 2
ATAT1 alpha tubulin acetyltransferase 1
BHMT2 betaine--homocysteine S-methyltransferase 2
BOLA1 bolA family member 1
BTF3P11 basic transcription factor 3 pseudogene 11
C11ORF63 chromosome 11 open reading frame 63
C1QTNF3 C1q and tumor necrosis factor related protein 3
C7ORF43 chromosome 7 open reading frame 43
C9ORF91 chromosome 9 open reading frame 91
CCDC33 coiled-coil domain containing 33
CCDC85C coiled-coil domain containing 85C
CDK6 cyclin-dependent kinase 6
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CECR1 cat eye syndrome chromosome region, candidate 1
CELP carboxyl ester lipase pseudogene
CENPJ centromere protein J
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
CPNE7 copine VII
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DHRS11 dehydrogenase/reductase (SDR family) member 11
DNAL4 dynein, axonemal, light chain 4
DSPP dentin sialophosphoprotein
EYA3 EYA transcriptional coactivator and phosphatase 3
FBXL7 F-box and leucine-rich repeat protein 7
FHOD1 formin homology 2 domain containing 1
FOXN2 forkhead box N2
FRMPD1 FERM and PDZ domain containing 1
GAREM GRB2 associated, regulator of MAPK1
GBP2 guanylate binding protein 2, interferon-inducible
GPR35 G protein-coupled receptor 35
HOXA2 homeobox A2
HOXC10 homeobox C10
IBSP integrin-binding sialoprotein
ICK intestinal cell (MAK-like) kinase
IL11RA interleukin 11 receptor, alpha
INO80D INO80 complex subunit D
JPH3 junctophilin 3
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
LAD1 ladinin 1
LINC00260 long intergenic non-protein coding RNA 260
LOC100286895 cell division cycle 27 homolog pseudogene
LTA lymphotoxin alpha
LTB lymphotoxin beta (TNF superfamily, member 3)
LY6D lymphocyte antigen 6 complex, locus D
LZTR1 leucine-zipper-like transcription regulator 1
METRN meteorin, glial cell differentiation regulator
MMP9 matrix metallopeptidase 9
MRAS muscle RAS oncogene homolog
MUC6 mucin 6, oligomeric mucus/gel-forming
MYH4 myosin, heavy chain 4, skeletal muscle
NINJ2 ninjurin 2
NNAT neuronatin
NPPB natriuretic peptide B
PADI2 peptidyl arginine deiminase, type II
PCDH12 protocadherin 12
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PECR peroxisomal trans-2-enoyl-CoA reductase
PFN2 profilin 2
PIP prolactin-induced protein
PLA2G3 phospholipase A2, group III
PMP22 peripheral myelin protein 22
RAB40A RAB40A, member RAS oncogene family
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RIN1 Ras and Rab interactor 1
RWDD2A RWD domain containing 2A
S1PR4 sphingosine-1-phosphate receptor 4
SCD5 stearoyl-CoA desaturase 5
SCRT1 scratch family zinc finger 1
SIGLEC15 sialic acid binding Ig-like lectin 15
SIRT2 sirtuin 2
SIT1 signaling threshold regulating transmembrane adaptor 1
SLC16A4 solute carrier family 16, member 4
SLC16A6 solute carrier family 16, member 6
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SNAI1 snail family zinc finger 1
SRPX sushi-repeat containing protein, X-linked
STAG3L4 stromal antigen 3-like 4 (pseudogene)
TBXAS1 thromboxane A synthase 1 (platelet)
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TIMP2 TIMP metallopeptidase inhibitor 2
TMEM120B transmembrane protein 120B
TMEM140 transmembrane protein 140
TMEM209 transmembrane protein 209
TOM1 target of myb1 (chicken)
TOR4A torsin family 4, member A
ZNF10 zinc finger protein 10
ZNF155 zinc finger protein 155
ZNF177 zinc finger protein 177
ZNF408 zinc finger protein 408
ZNF787 zinc finger protein 787
ZNF862 zinc finger protein 862