suprofen-3343 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the suprofen-3343 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
AHSP alpha hemoglobin stabilizing protein
ALCAM activated leukocyte cell adhesion molecule
ALDOAP2 aldolase A, fructose-bisphosphate pseudogene 2
ALK anaplastic lymphoma receptor tyrosine kinase
ALOX15 arachidonate 15-lipoxygenase
ARPIN actin-related protein 2/3 complex inhibitor
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
AUTS2 autism susceptibility candidate 2
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BDKRB1 bradykinin receptor B1
BGLAP bone gamma-carboxyglutamate (gla) protein
BLZF1 basic leucine zipper nuclear factor 1
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
C19ORF73 chromosome 19 open reading frame 73
CAPN9 calpain 9
CASP10 caspase 10, apoptosis-related cysteine peptidase
CDHR2 cadherin-related family member 2
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CLIC5 chloride intracellular channel 5
CNPY4 canopy FGF signaling regulator 4
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DFNB31 deafness, autosomal recessive 31
DHRS12 dehydrogenase/reductase (SDR family) member 12
DOK4 docking protein 4
DRD2 dopamine receptor D2
EDNRA endothelin receptor type A
FAM198B family with sequence similarity 198, member B
FHL1 four and a half LIM domains 1
FLNC filamin C, gamma
FLOT1 flotillin 1
FYB FYN binding protein
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GBP1 guanylate binding protein 1, interferon-inducible
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GPATCH4 G patch domain containing 4
GRM1 glutamate receptor, metabotropic 1
HOXA10 homeobox A10
IDS iduronate 2-sulfatase
IHH indian hedgehog
IRS4 insulin receptor substrate 4
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3
KDM8 lysine (K)-specific demethylase 8
KLF13 Kruppel-like factor 13
LRP4 low density lipoprotein receptor-related protein 4
LRRC15 leucine rich repeat containing 15
LRRC48 leucine rich repeat containing 48
NBL1 neuroblastoma 1, DAN family BMP antagonist
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
NF1 neurofibromin 1
NKX2-5 NK2 homeobox 5
NUP54 nucleoporin 54kDa
NYNRIN NYN domain and retroviral integrase containing
OR2B6 olfactory receptor, family 2, subfamily B, member 6
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PARP11 poly (ADP-ribose) polymerase family, member 11
PDE3B phosphodiesterase 3B, cGMP-inhibited
PDE4D phosphodiesterase 4D, cAMP-specific
PER1 period circadian clock 1
PGAM2 phosphoglycerate mutase 2 (muscle)
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
PLEKHS1 pleckstrin homology domain containing, family S member 1
PLXNB2 plexin B2
POMT2 protein-O-mannosyltransferase 2
PPARA peroxisome proliferator-activated receptor alpha
PSCA prostate stem cell antigen
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
PTGDS prostaglandin D2 synthase 21kDa (brain)
RASA3 RAS p21 protein activator 3
RIMS3 regulating synaptic membrane exocytosis 3
RIN3 Ras and Rab interactor 3
RND1 Rho family GTPase 1
RNF32 ring finger protein 32
RUNX1 runt-related transcription factor 1
SECTM1 secreted and transmembrane 1
SGK2 serum/glucocorticoid regulated kinase 2
SH3BP2 SH3-domain binding protein 2
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SORBS1 sorbin and SH3 domain containing 1
SYK spleen tyrosine kinase
TAT tyrosine aminotransferase
TJAP1 tight junction associated protein 1 (peripheral)
TNC tenascin C
TRA T cell receptor alpha locus
TSC22D2 TSC22 domain family, member 2
TSPAN9 tetraspanin 9
UHRF1BP1L UHRF1 binding protein 1-like
UMOD uromodulin
VIM vimentin
WDTC1 WD and tetratricopeptide repeats 1
YPEL1 yippee-like 1 (Drosophila)
ZC2HC1C zinc finger, C2HC-type containing 1C
ZNF518A zinc finger protein 518A
ZNF646 zinc finger protein 646

decreased expression

Symbol Name
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ABLIM3 actin binding LIM protein family, member 3
ATG2A autophagy related 2A
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BAG4 BCL2-associated athanogene 4
BAHCC1 BAH domain and coiled-coil containing 1
BCL2L2 BCL2-like 2
BMP4 bone morphogenetic protein 4
C14ORF132 chromosome 14 open reading frame 132
C5 complement component 5
CAMK1 calcium/calmodulin-dependent protein kinase I
CCNK cyclin K
CD82 CD82 molecule
CENPO centromere protein O
CEP97 centrosomal protein 97kDa
CORO7 coronin 7
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DGAT1 diacylglycerol O-acyltransferase 1
DMTN dematin actin binding protein
DNAL4 dynein, axonemal, light chain 4
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EDAR ectodysplasin A receptor
EGFL7 EGF-like-domain, multiple 7
ELOVL4 ELOVL fatty acid elongase 4
ENO3 enolase 3 (beta, muscle)
ETAA1 Ewing tumor-associated antigen 1
EXOC6B exocyst complex component 6B
FAM155B family with sequence similarity 155, member B
FBRS fibrosin
FKBP10 FK506 binding protein 10, 65 kDa
FKBPL FK506 binding protein like
FLJ11710 uncharacterized protein FLJ11710
FPGT fucose-1-phosphate guanylyltransferase
GDAP1 ganglioside induced differentiation associated protein 1
GPR143 G protein-coupled receptor 143
H1F0 H1 histone family, member 0
HDAC5 histone deacetylase 5
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
IFT140 intraflagellar transport 140
IL17RA interleukin 17 receptor A
IL22 interleukin 22
KLHL25 kelch-like family member 25
KLK5 kallikrein-related peptidase 5
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MATK megakaryocyte-associated tyrosine kinase
MVD mevalonate (diphospho) decarboxylase
MYOZ3 myozenin 3
NIPAL2 NIPA-like domain containing 2
NPIPB3 nuclear pore complex interacting protein family, member B3
NPM3 nucleophosmin/nucleoplasmin 3
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PCDHGB5 protocadherin gamma subfamily B, 5
PCSK7 proprotein convertase subtilisin/kexin type 7
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PLCD1 phospholipase C, delta 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PMCH pro-melanin-concentrating hormone
POLL polymerase (DNA directed), lambda
POPDC3 popeye domain containing 3
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PRSS16 protease, serine, 16 (thymus)
RAB30 RAB30, member RAS oncogene family
RASAL1 RAS protein activator like 1 (GAP1 like)
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RGS17 regulator of G-protein signaling 17
RLN1 relaxin 1
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
SAV1 salvador family WW domain containing protein 1
SLC12A8 solute carrier family 12, member 8
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
STARD3 StAR-related lipid transfer (START) domain containing 3
STRA6 stimulated by retinoic acid 6
SYBU syntabulin (syntaxin-interacting)
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TCTN2 tectonic family member 2
THBS3 thrombospondin 3
THRAP3 thyroid hormone receptor associated protein 3
THRB thyroid hormone receptor, beta
TLR5 toll-like receptor 5
TMEM38B transmembrane protein 38B
TRAIP TRAF interacting protein
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TUBA3C tubulin, alpha 3c
TYK2 tyrosine kinase 2
USP20 ubiquitin specific peptidase 20
VGF VGF nerve growth factor inducible
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZFHX2 zinc finger homeobox 2
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF10 zinc finger protein 10
ZNF250 zinc finger protein 250
ZNF276 zinc finger protein 276
ZNF428 zinc finger protein 428
ZSCAN26 zinc finger and SCAN domain containing 26